ChemicalBook > CAS DataBase List > tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate

tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate

Product Name
tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate
CAS No.
869494-16-6
Chemical Name
tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate
Synonyms
tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate;DM1Impurity14;3,6-DiazabicycL;o[3.1.1]heptane-6-carboxyL;6-Boc-3,6-diaza-bicyclo[3.1.1]heptane;6-(tert-Butyloxycarbonyl)-3,6-diazabicyclo[3.1.1]heptane;tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate 97%;3,6-Diazbiclo[.1.1]heptane-6-carboxylic acid tert-butyl ester;tert-Butyl (1S,5R)-3,6-diazabicyclo[3.1.1]heptane-6-carboxylate;(1R,5S)-tert-butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate
CBNumber
CB12534807
Molecular Formula
C10H18N2O2
Formula Weight
198.26
MOL File
869494-16-6.mol
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tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate Property

Boiling point:
276℃
Density 
1.104
Flash point:
121℃
storage temp. 
2-8°C(protect from light)
pka
9.53±0.20(Predicted)
form 
solid
color 
White to off-white
InChI
InChI=1S/C10H18N2O2/c1-10(2,3)14-9(13)12-7-4-8(12)6-11-5-7/h7-8,11H,4-6H2,1-3H3
InChIKey
OUFBVDKNEWUFHP-UHFFFAOYSA-N
SMILES
C12CC(N1C(OC(C)(C)C)=O)CNC2
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
B789735
Product name
tert-Butyl3,6-diazabicyclo[3.1.1]heptane-6-carboxylate
Packaging
250mg
Price
$40
Updated
2021/12/16
Usbiological
Product number
263598
Product name
6-Boc-3,6-diazabicyclo[3.1.1]heptane
Packaging
50mg
Price
$509
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB29383
Product name
6-Boc-3,6-diazabicyclo[3.1.1]heptane
Packaging
500mg
Price
$400
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB29383
Product name
6-Boc-3,6-diazabicyclo[3.1.1]heptane
Packaging
1g
Price
$500
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0394022
Product name
TERT-BUTYL-3,6-DIAZABICYCLO[3.1.1]HEPTANE-6-CARBOXYLATE
Purity
95.00%
Packaging
5MG
Price
$503.81
Updated
2021/12/16
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tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate Chemical Properties,Usage,Production

Synthesis

To a stirred solution of 3,6-Diazabicyclo[3.1.1]heptane-6-carboxylic acid, 3-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester (400 mg, 1.04 mmol) in DMF (2.5 mL) were added dodecanethiol (500 μL, 2.09 mmol) and lithium hydroxide hydrate (88 mg, 2.09 mmol). The mixture was stirred at r.t. for 2 h. The mixture was diluted with hexanes-ethyl acetate (10 mL, 1:1). The mixture was extracted with aq. Hydrochloric acid (2 x 5.0 mL). The aq. layer was extracted with hexanes-ethyl acetate (10 mL, 1:1). The combined organic layers were discarded. The aq. layer was basified with NaOH (6.0 mL of 1.0 M solution) until pH=13. The aq. layer was extracted with methylene chloride-methanol (2 x 10 mL, 9:1). The organic layer was washed with brine, dried over anhydrous magnesium sulfate, filtered and concentrated in vacuo to afford tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate as a white solid; Yield, 167 mg (81percent)

tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate Suppliers

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View Lastest Price from tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate manufacturers

Henan Fengda Chemical Co., Ltd
Product
3,6-Diazabicyclo[3.1.1]heptane-6-carboxylic acid tert-butyl ester 869494-16-6
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Henan Aochuang Chemical Co.,Ltd.
Product
3,6-Diazabicyclo[3.1.1]heptane-6-carboxylic acid tert-butyl ester 869494-16-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-08
Career Henan Chemical Co
Product
3,6-Diazabicyclo[3.1.1]heptane-6-carboxylic acid tert-butyl ester 869494-16-6
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-10

869494-16-6, tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylateRelated Search:

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate tert-butyl (S)-3-(4-bromophenyl)piperidine-1-carboxylate 5-Amino-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid tert-butyl ester tert-butyl (S)-(1-(3-aminophenyl)ethyl)carbamate tert-butyl-trans-3,4-dihydroxypyrrolidine-1-carboxylate tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate tert-Butyl 4-(pyrrolidin-3-yl)piperidine-1-carboxylate Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) tert-butyl 6-hydroxy-3-azabicyclo[3.1.0]hexane-3-carboxylate Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) 1-Methyl-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester tert-butyl [3,4'-bipiperidine]-1'-carboxylate TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,6-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE tert-butyl 4-(azetidin-3-yl)piperidine-1-carboxylate (3R,4S)-tert-butyl 3,4-dihydroxypyrrolidine-1-carboxylate N-BOC-3A,4,7,7A-TETRAHYDROISOINDOLE tert-butyl 3,8-diazabicyclo[3.2.1]octane-3-carboxylate tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate

  • 3,6-Diazabicyclo[3.1.1]heptane-6-carboxylic acid tert-butyl ester
  • 6-(tert-Butyloxycarbonyl)-3,6-diazabicyclo[3.1.1]heptane
  • (1R,5S)-tert-butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate
  • 3,6-Diazabicyclo[3.1.1]heptane-6-carboxylic acid, 1,1-dimethylethyl ester
  • tert-Butyl (1S,5R)-3,6-diazabicyclo[3.1.1]heptane-6-carboxylate
  • 6-Boc-3,6-diaza-bicyclo[3.1.1]heptane
  • tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate
  • 3,?6-?Diazabicyclo[3.1.1]?heptane-?6-?carboxylic acid, 1,?1-?dimethylethyl ester 869494-16-6
  • tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-6-carboxylate 97%
  • o[3.1.1]heptane-6-carboxyL
  • 3,6-DiazabicycL
  • DM1Impurity14
  • 36-Diazabicyclo131.1heptan e-6-carboxylic acid tert-butyl ester
  • 3,6-Diazbiclo[.1.1]heptane-6-carboxylic acid tert-butyl ester
  • 869494-16-6