tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate

Product Name: tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
CAS No.: 1198408-35-3
Chemical Name: tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
Synonyms: tert-Butyl 4-(6-aminopyridin-3-yl);4-(6-Amino-3-pyridyl)-1-Boc-piperidine;4-(6-aminopyridin-3-yl)piperidine-1-carboxylate;ert-butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate;tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester;tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate ISO 9001：2015 REACH;6-amino-3',4',5',6'-tetrahydro-2'H-[3,4']bipyridinyl-1'-carboxylicacidtert-butylester
CBNumber: CB12594133
Molecular Formula: C15H23N3O2
Formula Weight: 277.36
MOL File: 1198408-35-3.mol

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tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Property

Boiling point:: 422.8±45.0 °C(Predicted)
Density: 1.134±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 6.80±0.26(Predicted)
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C15H23N3O2/c1-15(2,3)20-14(19)18-8-6-11(7-9-18)12-4-5-13(16)17-10-12/h4-5,10-11H,6-9H2,1-3H3,(H2,16,17)
InChIKey: UGJYTOMOCDGLRS-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC(C2=CC=C(N)N=C2)CC1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B811320
Product name: tert-Butyl4-(6-Aminopyridin-3-yl)piperidine-1-carboxylate
Packaging: 100mg
Price: $265
Updated: 2021/12/16

AK Scientific

Product number: 3427DH
Product name: Tert-butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate
Packaging: 1g
Price: $667
Updated: 2021/12/16

Ambeed

Product number: A331079
Product name: tert-Butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate
Purity: 95%
Packaging: 5g
Price: $747
Updated: 2021/12/16

A1 Biochem Labs

Product number: 6594354
Product name: tert-Butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate
Purity: 95%
Packaging: 2.5g
Price: $900
Updated: 2021/12/16

Crysdot

Product number: CD11333802
Product name: tert-Butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate
Purity: 95+%
Packaging: 5g
Price: $1337
Updated: 2021/12/16

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tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Chemical Properties,Usage,Production

Synthesis

1231930-22-5

1198408-35-3

In a 500 mL round-bottomed flask, tert-butyl 4-(6-nitropyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate (4.9 g, 16.0 mmol, 1.00 equiv.) was dissolved in a solvent mixture of ethanol (300 mL) and ethyl acetate (75 mL) and palladium carbon (1.32 g, 1.24 mmol, 0.0773 equiv.) was added. The reaction mixture was displaced twice with hydrogen and then stirred overnight under a hydrogen atmosphere (using a hydrogen balloon). The completion of the reaction was confirmed by LC/MS analysis. The reaction mixture was purged with nitrogen and filtered through a diatomaceous earth pad, which was washed several times with ethyl acetate. The colorless filtrate and washings were combined, dichloromethane was added and the solution was evaporated to dryness. Dichloromethane was added again and the solution was concentrated under vacuum to give the target product tert-butyl 4-(6-aminopyridin-3-yl)piperidine-1-carboxylate in quantitative yield. (M + H)+ = 278 m/z.

References

[1] Patent: WO2013/24078, 2013, A1. Location in patent: Page/Page column 57; 58
[2] Patent: CN106608879, 2017, A. Location in patent: Paragraph 0268-0269; 0273-0274
[3] Patent: WO2014/83026, 2014, A1. Location in patent: Page/Page column 26; 47-48
[4] Patent: CN105622638, 2016, A. Location in patent: Paragraph 0181
[5] Patent: US2018/297995, 2018, A1. Location in patent: Paragraph 0046; 0051; 0052

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Preparation Products And Raw materials

Raw materials

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tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Suppliers

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View Lastest Price from tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate 1198408-35-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-08

Shaanxi Dideu New Materials Co. Ltd

Product: tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate 1198408-35-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-22

Career Henan Chemical Co

Product: tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate 1198408-35-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2020-03-05

1198408-35-3, tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylateRelated Search:

tert-butyl 4-(6-((4-ethynyl-2-fluorobenzyl)oxy)-5-fluoropyridin-2-yl)piperazine-1-carboxylate 1-Piperidinecarboxylic acid, 4-(6-chloro-2-pyridinyl)-, 1,1-dimethylethyl ester tert-butyl 4-(6-((4-ethynyl-2-fluorobenzyl)oxy)-5-methylpyridin-2-yl)piperazine-1-carboxylate tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate tert-butyl 3,8-diazabicyclo[3.2.1]octane-3-carboxylate tert-butyl 4-(azetidin-3-yl)piperidine-1-carboxylate tert-butyl 3-bromo-2,5-dihydro-1H-pyrrole-1-carboxylate tert-Butyl 4-(pyrrolidin-3-yl)piperidine-1-carboxylate 3,6-Diazabicyclo[3.1.1]heptane-6-carboxylic acid tert-butyl ester tert-Butyl 4-(6-chloropyridin-2-yl)piperazine-1-carboxylate 2-Bromo-6-(N-Boc-piperidin-4-yl)pyridine 4-BOC-1-(6-BROMO-2-PYRIDYL)PIPERAZINE INDEX NAME NOT YET ASSIGNED 4-(4-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-Piperazinecarboxylic acid, 4-(4-piperidinylmethyl)-, 1,1-dimethylethyl ester tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 4-Aminomethyl-4-fluoro-piperidine-1-carboxylic acid tert-butyl ester 1-BOC-4-(4-HYDROXY-PHENYL)-PIPERAZINE

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate

tert-Butyl 4-(6-aminopyridin-3-yl)

4-(6-Amino-3-pyridyl)-1-Boc-piperidine

1-Piperidinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester

ert-butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate ISO 9001：2015 REACH

6-amino-3',4',5',6'-tetrahydro-2'H-[3,4']bipyridinyl-1'-carboxylicacidtert-butylester

4-(6-aminopyridin-3-yl)piperidine-1-carboxylate

1198408-35-3