ChemicalBook > CAS DataBase List > m-PEG8-NHS ester
m-PEG8-NHS ester
- Product Name
- m-PEG8-NHS ester
- CAS No.
- 756525-90-3
- Chemical Name
- m-PEG8-NHS ester
- Synonyms
- m-dPEG(R)8-NHS ester;Methyl-PEG8-NHS Ester;MPEG7-NHS;mPEG7-SPA;mPEG7-C2-NHS;MeO-dPEG(8)-NHS;m-dPEG®m-PEG8-NHS ester;m-dPEG8-NHS ester;Methyl-PEG7-NHS ester
- CBNumber
- CB12546950
- Molecular Formula
- C22H39NO12
- Formula Weight
- 509.54
- MOL File
- 756525-90-3.mol
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m-PEG8-NHS ester Property
- storage temp.
- -20°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- solid or viscous liquid
- color
- Colorless to Yellow
- InChI
- InChI=1S/C22H39NO12/c1-27-6-7-29-10-11-31-14-15-33-18-19-34-17-16-32-13-12-30-9-8-28-5-4-22(26)35-23-20(24)2-3-21(23)25/h2-19H2,1H3
- InChIKey
- IBZNTYBFTKFSMU-UHFFFAOYSA-N
- SMILES
- C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOC
- CAS DataBase Reference
- 756525-90-3
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Safety
- HS Code
- 2942000090
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- QBD10260
- Product name
- m-dPEG®8-NHS ester
- Packaging
- 100MG
- Price
- $129.5
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- QBD10260
- Product name
- m-dPEG®8-NHS ester
- Packaging
- 1000MG
- Price
- $739
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M2187
- Product name
- Methyl-PEG8-NHS Ester
- Packaging
- 25mg
- Price
- $81
- Updated
- 2025/07/31
Chem-Impex
- Product number
- 41717
- Product name
- Methyl-PEG8-NHSester,≥90%
- Purity
- ≥90%
- Packaging
- 25MG
- Price
- $75.71
- Updated
- 2021/12/16
dPEG
- Product number
- 10260
- Product name
- m-dPEG®₈-NHSester
- Packaging
- 100mg
- Price
- $175
- Updated
- 2021/12/16
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m-PEG8-NHS ester Chemical Properties,Usage,Production
Description
m-PEG8-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
reaction suitability
reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: amine reactive
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References
[1] By Boehnke, et al. Preparation of antibody drug conjugates with NAMPT inhibitors for use in treatment of cancer. Patent WO2019149637A1.
m-PEG8-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
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m-PEG8-NHS ester Suppliers
- Tel
- +1-2266000236
- sales@rdscientific.com
- Country
- Canada
- ProdList
- 1902
- Advantage
- 58
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View Lastest Price from m-PEG8-NHS ester manufacturers
LAURENT
- Product
- mPEG7-CH2CH2COONHS ester 756525-90-3
- Price
- US $288.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-19
R&D Scientific Inc.
- Product
- m-PEG8-NHS ester 756525-90-3
- Price
- US $1490.00/g
- Min. Order
- 1g
- Purity
- 99 %
- Supply Ability
- 500 Kg
- Release date
- 2025-09-12
Xian confluore Biological Technology Co., Ltd.
- Product
- m-PEG8-NHS ester 756525-90-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >95.00%
- Supply Ability
- 1g
- Release date
- 2024-03-27
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