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Sodium salicylate

Product Name
Sodium salicylate
CAS No.
54-21-7
Chemical Name
Sodium salicylate
Synonyms
SALICYLATE;NASAL;alysine;2-Hydroxybenzoate;clin;ardall;aroall;kerosal;nadisal;salisod
CBNumber
CB1255762
Molecular Formula
C7H5NaO3
Formula Weight
160.1
MOL File
54-21-7.mol
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Sodium salicylate Property

Melting point:
>300 °C (lit.)
Density 
0.32 g/cm3 (20℃)
storage temp. 
Store at +15°C to +25°C.
solubility 
1000g/l
form 
Crystals or Crystalline Powder
color 
White
PH
6.5 (100g/l, H2O, 20℃)
Odor
wh. lustrous cryst. scales or amorphous powd., odorless or faint odor, saline taste
Water Solubility 
1000 g/L (20 ºC)
Sensitive 
Light Sensitive
Merck 
14,8332
BRN 
3732792
Stability:
Stable. Incompatible with mineral acids, metallic salts, iodine. May be light-sensitive.
InChIKey
ABBQHOQBGMUPJH-UHFFFAOYSA-M
LogP
2.061 (est)
CAS DataBase Reference
54-21-7(CAS DataBase Reference)
EPA Substance Registry System
Sodium salicylate (54-21-7)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-41-36/37/38-36
Safety Statements 
26-36
WGK Germany 
1
RTECS 
VO5075000
F 
8
Autoignition Temperature
>250 °C
TSCA 
Yes
HS Code 
29182100
Toxicity
LD50 i.p. in rats: 780 mg/kg (Goldenthal)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3238
Product name
Sodium Salicylate
Purity
pharmaceutical secondary standard, certified reference material
Packaging
1G
Price
$173
Updated
2024/03/01
Sigma-Aldrich
Product number
567630
Product name
Sodium Salicylate - CAS 54-21-7 - Calbiochem
Purity
A cell-permeable, non-steroidal anti-inflammatory agent that interferes with TNF-induced NF-κB activation by inhibiting phosphorylation and subsequent degradation of the IκB-α protein.
Packaging
5G
Price
$56.2
Updated
2024/03/01
Sigma-Aldrich
Product number
31493
Product name
Sodium salicylate
Purity
puriss. p.a., Reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)
Packaging
1kg
Price
$208
Updated
2024/03/01
Sigma-Aldrich
Product number
1.06601
Product name
Sodium salicylate
Purity
for analysis EMSURE?
Packaging
250g
Price
$79.1
Updated
2024/03/01
Sigma-Aldrich
Product number
1614636
Product name
Sodium salicylate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
500mg
Price
$420
Updated
2024/03/01
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Sodium salicylate Chemical Properties,Usage,Production

Description

Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure. Historically, it has been synthesized from methyl salicylate (found in wintergreen plants or the bark of sweet birch tree) by reacting it with an excess of sodium hydroxide and heating it under reflux.

Chemical Properties

Sodium salicylate is of the salicylate family and this compound is known to trigger Reye's Syndrome in children and adults, usually following a viral infection such as influenza or chicken pox. Products containing such salicylates should not be given to children under the age of 19.

Chemical Properties

Sodium salicylate, HOC6H4COONa, is a shiny, white powder with sweetish taste and mild aromatic aroma that is soluble in water,glycerol, and alcohol.Used in medicine and as a preservative.

Uses

It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non - steroidal anti - inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. It is also a potential replacement for aspirin for people sensitive to it. It may also be used as a phosphor for the detection of vacuum ultra violet radiation and electrons.

Uses

keratolytic

Uses

In manufacture of aspirin, methyl salicylate, and other salicylates. Coupling agent for azo dyes. Has been used as food preservative.

Definition

A salt or ester of salicylic acid.

brand name

Alysine (Marion Merrell Dow).

General Description

Sodium salicylate may be prepared by the reaction, in aqueoussolution, by adding equal molar ratio of salicylic acidand sodium bicarbonate; evaporating to dryness yields thewhite salt. In solution, particularly in the presence of sodiumbicarbonate, the salt will darken on standing. This is the saltof choice for salicylate medication and usually is administeredwith sodium bicarbonate to lessen gastric distress, or itis administered in enteric coated tablets. However, the useof sodium bicarbonate is ill advised, because it decreases theplasma levels of salicylate and increases the excretion offree salicylate in the urine.
Sodium salicylate, even though not as potent as aspirinfor pain relief, also has less GI irritation and is useful for patientswho are hypersensitive to aspirin.

Biochem/physiol Actions

Cell permeable: yes

Safety Profile

Experimental poison by subcutaneous route. Moderately toxic to humans by ingestion. Moderately toxic experimentally by ingestion, intraperitoneal, and intravenous routes. An experimental teratogen. Human systemic effects by multiple and unspecified routes: toxic psychosis, excitement, respiratory stimulation, nausea or vomiting, and sweating. Experimental reproductive effects. Mutation data reported. A powerful irritant which affects the central nervous system. Incompatible with ferric salts, mineral acids, iodme, lead acetate, silver nitrate, sodium phosphate powder. When heated to decomposition it emits toxic fumes of Na2O.

Sodium salicylate Preparation Products And Raw materials

Raw materials

Sodium dithionite Salicylic acid Ethylenediaminetetraacetic acid

Preparation Products

3,6-DICHLORO-2-HYDROXY BENZOIC ACID Salicylic acid Benzyl salicylate Mordant Yellow 1
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View Lastest Price from Sodium salicylate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Sodium salicylate 54-21-7
Price
US $0.00/KG
Min. Order
25KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-09
Hebei Weibang Biotechnology Co., Ltd
Product
Sodium salicylate 54-21-7
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Henan Suikang Pharmaceutical Co.,Ltd.
Product
Sodium salicylate 54-21-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.0%
Supply Ability
1tons
Release date
2024-04-26

54-21-7, Sodium salicylateRelated Search:

Sodium hydroxide Sodium 4-hydroxybenzoate Sodium benzoate Sodium bicarbonate Diclofenac sodium Methyl salicylate Salicylic acid P-AMINOSALICYLIC ACID SODIUM SALT Sodium citrate Trisodium phosphate Sodium acetate SALICYLIC ACID N-PROPYL ESTER 2-Cyanophenol 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Salicylaldoxime Benzyl salicylate AMMONIUM SALICYLATE 2-Hydroxyethyl salicylate Sodium Salicylate Solution

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