6-Aminobenzothiazole
- Product Name
- 6-Aminobenzothiazole
- CAS No.
- 533-30-2
- Chemical Name
- 6-Aminobenzothiazole
- Synonyms
- BUTTPARK 98\57-13;6-BENZOTHIAZOLAMINE;benzothiazol-6-amine;6-AMINOBENZOTHIAZOLE;6-amino-benzothiazol;Benzothiazole-6-amine;BENZOTHIAZOL-6-YLAMINE;benzo[d]thiazol-6-amine;6-AMinobenzo[d]thiazole;1,3-BENZOTHIAZOL-6-AMINE
- CBNumber
- CB1257443
- Molecular Formula
- C7H6N2S
- Formula Weight
- 150.2
- MOL File
- 533-30-2.mol
6-Aminobenzothiazole Property
- Melting point:
- 87-91 °C (lit.)
- Boiling point:
- 323.1±15.0 °C(Predicted)
- Density
- 1.2162 (rough estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform, Methanol (Slightly)
- form
- Solid
- pka
- 2.74±0.10(Predicted)
- color
- Yellow to Beige
- Water Solubility
- Slightly soluble in water.
- Merck
- 14,425
- BRN
- 116381
- InChIKey
- FAYAYUOZWYJNBD-UHFFFAOYSA-N
- CAS DataBase Reference
- 533-30-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-36/37/39-22
- WGK Germany
- 3
- RTECS
- DL1050200
- Hazard Note
- Irritant
- HS Code
- 29342000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 562440
- Product name
- 6-Aminobenzothiazole
- Purity
- 97%
- Packaging
- 1g
- Price
- $53.58
- Updated
- 2025/07/31
- Product number
- 562440
- Product name
- 6-Aminobenzothiazole
- Purity
- 97%
- Packaging
- 5g
- Price
- $242
- Updated
- 2025/07/31
- Product number
- A2898
- Product name
- 6-Aminobenzothiazole
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $133
- Updated
- 2024/03/01
- Product number
- A593505
- Product name
- 6-Aminobenzothiazole
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 072185
- Product name
- 6-Aminobenzothiazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
6-Aminobenzothiazole Chemical Properties,Usage,Production
Chemical Properties
Yellow solid
Uses
6-Aminobenzothiazole is used as pharmaceutical intermediate.
Uses
6-Aminobenzothiazole may be used in the synthesis of following:
- 1-(6-amino-benzothiazolyl)-3-chloro-5-methoxytriazine
- 6-[(4-N,N-dimethylaminophenyl)diazenyl]benzothiazole
- 6-[(2-hydroxy-1-naphthyl)diazenyl]benzothiazole
- 6-dimethylaminobenzothiazole
General Description
6-Aminobenzothiazole can be prepared from 6-nitrobenzothiazole via sonochemical reduction method.
Synthesis
2942-06-5
533-30-2
General procedure for the synthesis of 6-aminobenzothiazole from 6-nitrobenzothiazole: 6-nitrobenzothiazole (6.13 mmol) was dissolved in ethanol (30 mL), and 10% Pd/C catalyst was added (20% of the mass of 6-nitrobenzothiazole was used as catalyst). The mixture was placed in a Parr hydrogenation unit and reacted overnight at 50 psi hydrogen pressure. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under vacuum to remove the solvent. Finally, purification by fast chromatography using a 30%-40% ethyl acetate/hexane gradient elution gave pure 6-aminobenzothiazole.
Purification Methods
It crystallises from aqueous EtOH, pet ether or *C6H6/pet ether. The hydrochloride has m 305o(dec) from dilute HCl, and the picrate has m 185o(dec ) from Me2CO. [Boggust & Cocker J Chem Soc 360 1949, Beilstein 27 III/IV 4884.]
References
[1] Advanced Synthesis and Catalysis, 2010, vol. 352, # 11-12, p. 1834 - 1840
[2] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 19, p. 7002 - 7007
[3] Synthesis, 2005, # 4, p. 600 - 604
[4] Journal of Organic Chemistry, 2011, vol. 76, # 21, p. 8726 - 8736
[5] Molecules, 2014, vol. 19, # 1, p. 925 - 939
6-Aminobenzothiazole Preparation Products And Raw materials
Raw materials
Preparation Products
6-Aminobenzothiazole Suppliers
- Tel
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- Country
- Belgium
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- 6293
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View Lastest Price from 6-Aminobenzothiazole manufacturers
- Product
- 6-Aminobenzothiazole 533-30-2
- Price
- US $2600.00/Kg
- Min. Order
- 1Kg
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-05-21
- Product
- 6-Aminobenzothiazole 533-30-2
- Price
- US $8.00-3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-03
- Product
- 6-Aminobenzothiazole 533-30-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10