ChemicalBook > CAS DataBase List > (4-BroMobutyl)phosphonic acid

(4-BroMobutyl)phosphonic acid

Product Name
(4-BroMobutyl)phosphonic acid
CAS No.
1190-14-3
Chemical Name
(4-BroMobutyl)phosphonic acid
Synonyms
(4-BroMobutyl)phosphonic acid;Phosphonic acid, (4-bromobutyl)-;Phosphonic acid, (4-bromobutyl)- (6CI,7CI,9CI)
CBNumber
CB12610983
Molecular Formula
C4H10BrO3P
Formula Weight
217
MOL File
1190-14-3.mol
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(4-BroMobutyl)phosphonic acid Property

Melting point:
127.0 to 131.0 °C
Boiling point:
358.8±44.0 °C(Predicted)
Density 
1.709±0.06 g/cm3(Predicted)
pka
2.52±0.10(Predicted)
form 
powder to crystal
color 
White to Almost white
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Safety

RIDADR 
3261
HS Code 
2931.90.9051
HazardClass 
8
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

Precautionary statements

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P390Absorb spillage to prevent material damage.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
B5014
Product name
(4-Bromobutyl)phosphonic Acid
Purity
>98.0%(T)
Packaging
1g
Price
$622
Updated
2025/07/31
TCI Chemical
Product number
B5014
Product name
(4-Bromobutyl)phosphonic Acid
Purity
>98.0%(T)
Packaging
200mg
Price
$179
Updated
2025/07/31
TRC
Product number
B486388
Product name
(4-Bromobutyl)phosphonic Acid
Packaging
5mg
Price
$60
Updated
2021/12/16
TRC
Product number
B486388
Product name
(4-Bromobutyl)phosphonic Acid
Packaging
25mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR323069
Product name
4-Bromobutylphosphonic acid
Packaging
100mg
Price
$547
Updated
2021/12/16
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(4-BroMobutyl)phosphonic acid Chemical Properties,Usage,Production

Description

4-bromobutylphosphonic acid contains a bromine group and a phosphonic acid group. The bromine is a good leaving group. The hydrophilic properties of the PEG linkers increase the water solubility of the compound in aqueous media.

Uses

4-Bromobutylphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

(4-BroMobutyl)phosphonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1190-14-3, (4-BroMobutyl)phosphonic acidRelated Search:


  • (4-BroMobutyl)phosphonic acid
  • Phosphonic acid, (4-bromobutyl)- (6CI,7CI,9CI)
  • Phosphonic acid, (4-bromobutyl)-
  • 1190-14-3