ChemicalBook > CAS DataBase List > α-(4-Chlorophenyl)-2-Methyl-N-2-pyridinyl-1H-indole-3-MethanaMine
α-(4-Chlorophenyl)-2-Methyl-N-2-pyridinyl-1H-indole-3-MethanaMine
- Product Name
- α-(4-Chlorophenyl)-2-Methyl-N-2-pyridinyl-1H-indole-3-MethanaMine
- CAS No.
- 305372-78-5
- Chemical Name
- α-(4-Chlorophenyl)-2-Methyl-N-2-pyridinyl-1H-indole-3-MethanaMine
- Synonyms
- CCT036477;Wnt Pathway Inhibitor XI, CCT036477;N-((4-chlorophenyl)(2-methyl-1H-indol-3-yl)methyl)pyridin-2-amine;α-(4-Chlorophenyl)-2-Methyl-N-2-pyridinyl-1H-indole-3-MethanaMine;Wnt Pathway Inhibitor XI, CCT036477 - CAS 305372-78-5 - Calbiochem;1H-Indole-3-methanamine, α-(4-chlorophenyl)-2-methyl-N-2-pyridinyl-
- CBNumber
- CB12621741
- Molecular Formula
- C21H18ClN3
- Formula Weight
- 347.84
- MOL File
- 305372-78-5.mol
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α-(4-Chlorophenyl)-2-Methyl-N-2-pyridinyl-1H-indole-3-MethanaMine Property
- Melting point:
- >167°C (dec.)
- Boiling point:
- 546.0±45.0 °C(Predicted)
- Density
- 1.301±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: ≥20mg/mL (warm to 60°C)
- pka
- 17.33±0.30(Predicted)
- form
- powder
- color
- white to tan
- Stability:
- Light Sensitive
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0151
- Product name
- CCT036477
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $138
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 681674
- Product name
- Wnt Pathway Inhibitor XI, CCT036477
- Packaging
- 5mg
- Price
- $172
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML0151
- Product name
- CCT036477
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $428
- Updated
- 2024/03/01
Usbiological
- Product number
- 005838
- Product name
- CCT036477
- Packaging
- 25mg
- Price
- $446
- Updated
- 2021/12/16
TRC
- Product number
- C227900
- Product name
- CCT036477
- Packaging
- 25mg
- Price
- $135
- Updated
- 2021/12/16
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α-(4-Chlorophenyl)-2-Methyl-N-2-pyridinyl-1H-indole-3-MethanaMine Chemical Properties,Usage,Production
Uses
CCT036477 is an inhibitor of Wnt signaling. Studies show that CCT036477 does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes.
Definition
ChEBI: N-[(4-chlorophenyl)-(2-methyl-1H-indol-3-yl)methyl]-2-pyridinamine is a member of indoles.
α-(4-Chlorophenyl)-2-Methyl-N-2-pyridinyl-1H-indole-3-MethanaMine Preparation Products And Raw materials
Raw materials
Preparation Products
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