ChemicalBook > CAS DataBase List > 3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-

Product Name: 3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-
CAS No.: 120964-45-6
Chemical Name: 3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-
Synonyms: DZNepHCl;NSC 617989 HCl;DZNEP; NSC 617989;DZNep hydrochloride;3-deazaneplanocin A HCl;NSC 617989 hydrochloride;3-deazaneplanocin A (DZNeP) HCl;3-Deazaneplanocin hydrochloride;DZNeP (3-deazaneplanocin A) HCl;3-Deazaneplanocin A (hydrochloride)
CBNumber: CB12623932
Molecular Formula: C12H15ClN4O3
Formula Weight: 298.7255
MOL File: 120964-45-6.mol

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3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- Property

Melting point:: 168-169℃
storage temp.: -20°C
solubility: H2O: ≥5mg/mL
form: Tan solid
color: white to beige
optical activity: [α]/D -88 to -108°, c =0.1 in water
Water Solubility: Soluble in water (10mM)
InChI: InChI=1/C12H14N4O3.ClH/c13-12-9-7(1-2-14-12)16(5-15-9)8-3-6(4-17)10(18)11(8)19;/h1-3,5,8,10-11,17-19H,4H2,(H2,13,14);1H/t8-,10-,11+;/s3
InChIKey: UNSKMHKAFPRFTI-FDKLLANESA-N
SMILES: C1[C@@H]([n]2c3ccnc(N)c3nc2)[C@H](O)[C@H](O)C=1CO.Cl |&1:1,12,14,r|

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0305
Product name: 3-Deazaneplanocin A hydrochloride
Purity: ≥97% (HPLC)
Packaging: 1mg
Price: $486
Updated: 2025/07/31

Sigma-Aldrich

Product number: 252790
Product name: Histone Methyltransferase EZH2 Inhibitor, DZNep
Packaging: 2mg
Price: $328
Updated: 2025/07/31

Cayman Chemical

Product number: 11102
Product name: 3-Deazaneplanocin A (hydrochloride)
Purity: ≥98%
Packaging: 500μg
Price: $92
Updated: 2024/03/01

Cayman Chemical

Product number: 11102
Product name: 3-Deazaneplanocin A (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $174
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0305
Product name: 3-Deazaneplanocin A hydrochloride
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $1630
Updated: 2025/07/31

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3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- Chemical Properties,Usage,Production

Uses

3-Deazaneplanocin A is a a powerful inhibitor of S-adenosylhomocysteine hydrolase that has shown potent and selective in vitro and in vivo antiviral activities.

Uses

3-Deazaneplanocin A hydrochloride has been used to test its effect on ovarian tumor progression. It has also been used as a S-adenosyl homocysteine hydrolase (SAH) inhibitor in c33A2 cells.

General Description

3-Deazaneplanocin A hydrochloride is a carbocyclic analog of adenosine. It has antimetastatic?property. It is used to treat Ebola virus disease, gastric cancer, myeloma and lymphoma.

Biochem/physiol Actions

3-Deazaneplanocin A (DZNep) is an S-Adenosylhomocysteine Hydrolase inhibitor and histone methyltransferase EZH2 inhibitor. It switches on repressed tumor suppressor genes and induces apoptosis by inhibiting the expression of EZH2.

target

histone methyltransferase

storage

-20°C

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- Suppliers

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View Lastest Price from 3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-Deazaneplanocin A hydrochloride 120964-45-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-Deazaneplanocin A hydrochloride 120964-45-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Career Henan Chemical Co

Product: 3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- 120964-45-6
Price: US $1.00/g
Min. Order: 1g
Purity: 99.99%
Supply Ability: 200kg
Release date: 2019-12-23

120964-45-6, 3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-Related Search:

Tazemetostat Saracatinib GSK 343 PD 0325901 ALK5 inhibitor II CHIR-99021

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)-

3-Deazaneplanocin A (hydrochloride)

3-Deazaneplanocin hydrochloride

DZNep hydrochloride

DZNEP; NSC 617989

NSC 617989 hydrochloride

(-)-1-[(1R,4R,5S)-3-(HydroxyMethyl)-4,5-dihydroxy-2-cyclopenten-1-yl]4-aMinoiMidazo[4,5-c]pyridine hydrochloride DZNep hydrochloride

(1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride (1:1)

1H-Imidazo[4,5-c]pyridine, 3-cyclopentene-1,2-diol deriv.

3-deazaneplanocin A HCl

3-deazaneplanocin A (DZNeP) HCl

NSC 617989 HCl

(-)-1-[(1R,4R,5S)-3-(Hydroxymethyl)-4,5-dihydroxy-2-cyclopenten-1-yl]4-aminoimidazo[4,5-c]pyridine hydrochloride

Histone Methyltransferase EZH2 Inhibitor, DZNep

Histone Methyltransferase EZH2 Inhibitor, DZNep - CAS 120964-45-6 - Calbiochem

(1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride

3-Deazaneplanocin A (DZNep) hydrochloride

DZNEP HYDROCHLORIDE;NSC 617989 HYDROCHLORIDE;3-DEAZANEPLANOCIN HYDROCHLORIDE

3-deazaneplanocin A HCl (DZNep HCl)

DZNepHCl

3-Deazaneplanocin A hydrochloride (DZNep hydrochloride

3-Cyclopentene-1,2-diol, 5-(4-aMino-1H-iMidazo[4,5-c]pyridin-1-yl)-3-(hydroxyMethyl)-, (Hydrochloride) (1:1), (1S,2R,5R)- USP/EP/BP

(1S,2R,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol

DZNeP (3-deazaneplanocin A) HCl

3-Deazaneplanocin A hydrochloride (DZNep), Lysine methyltransferase EZH2 inhibitor

3-Deazaneplanocin hydrochloride - Bio-X ?

3-deazaneplanocin A (DZNeP) HCl ，S7120

120964-45-6

C12H14N4O3HCl

C12H14N4O3ClH

Inhibitors