ChemicalBook > CAS DataBase List > 1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-

1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-

Product Name
1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-
CAS No.
896720-20-0
Chemical Name
1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-
Synonyms
VX-11e;VX 11e;CS-1121;VTX-11e;Vertex-11e;TCS ERK 11e;VX-11E;VX 11E;VX-11e(TCS ERK 11e);TCS ERK 11e (VX-11e);VX 11E;VX11 E; TCS ERK 11E
CBNumber
CB12625365
Molecular Formula
C24H20Cl2FN5O2
Formula Weight
500.35
MOL File
896720-20-0.mol
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1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]- Property

Density 
1.447±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
≥25 mg/mL in DMSO; insoluble in H2O; ≥12.65 mg/mL in EtOH with ultrasonic
form 
solid
pka
13.65±0.50(Predicted)
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P233Keep container tightly closed.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19932
Product name
TCS ERK 11e
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
19932
Product name
TCS ERK 11e
Purity
≥98%
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
19932
Product name
TCS ERK 11e
Purity
≥98%
Packaging
10mg
Price
$213
Updated
2024/03/01
Cayman Chemical
Product number
19932
Product name
TCS ERK 11e
Purity
≥98%
Packaging
25mg
Price
$397
Updated
2024/03/01
Tocris
Product number
4465
Product name
TCSERK11e
Purity
≥98%(HPLC)
Packaging
10
Price
$293
Updated
2021/12/16
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1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]- Chemical Properties,Usage,Production

Uses

VX 11e is a pyrimidylpyrrole ERK inhibitor.

Definition

ChEBI: 4-[2-(2-chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide is a heteroarene and an aromatic amide.

storage

Store at -20°C

1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]- Suppliers

China 66 India 1 United Kingdom 1 United States 12 Global 80
Shanghai Zhengyi Pharmaceutical Co., Ltd
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17740884366
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derek1229@163.com
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China
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Shanghai Boyle Chemical Co., Ltd.
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sales@boylechem.com
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Chembest Research Laboratories Limited
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Haoyuan Chemexpress Co., Ltd.
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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AdooQ Bioscience CHINA
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025-68650336
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Shanghai Lollane Biological Technology Co.,Ltd.
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021-52996696，15000506266 15000506266
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+86-21-52996696
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D&C Chemicals
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View Lastest Price from 1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]- manufacturers

Career Henan Chemical Co
Product
1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]- 896720-20-0
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-08

896720-20-0, 1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-Related Search:

(S)-1-((S)-2-(4-amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide Lumacaftor (VX-809) VX-745 vx984 VX-222 VX-661 VX 702

  • VX-11e(TCS ERK 11e)
  • TCS ERK 11e
  • VX-11E;VX 11E
  • TCS ERK 11e (VX-11e)
  • 4-[2-[(2-Chloro-4-fluorophenyl)amino]-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide
  • 1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-
  • VX 11e
  • VX-11e
  • VX 11E;VX11 E; TCS ERK 11E
  • CS-1121
  • (S)-4-(2-((2-chloro-4-fluorophenyl)amino)-5-methylpyrimidin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide
  • Vertex-11e
  • VTX-11e
  • Extracellular signal regulated kinases,Inhibitor,inhibit,VX-11e,ERK,VX 11e,VX11e
  • 896720-20-0
  • C24H20Cl2FN5O2
  • Anti-cancer&immunity
  • MAPK