ChemicalBook > CAS DataBase List > FTI-277

FTI-277

Product Name
FTI-277
CAS No.
170006-73-2
Chemical Name
FTI-277
Synonyms
FTI-277;FTI-277;FTI277;METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA;N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester;N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester;N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
CBNumber
CB1266050
Molecular Formula
C22H29N3O3S2
Formula Weight
447.61
MOL File
170006-73-2.mol
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FTI-277 Property

Boiling point:
684.2±55.0 °C(Predicted)
Density 
1.222±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: soluble
form 
amorphous semi-solid
pka
9.81±0.10(Predicted)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F9803
Product name
FTI-277 trifluoroacetate salt
Purity
≥95% (HPLC), amorphous semi-solid
Packaging
1mg
Price
$190
Updated
2024/03/01
Sigma-Aldrich
Product number
F9803
Product name
FTI-277 trifluoroacetate salt
Purity
≥95% (HPLC), amorphous semi-solid
Packaging
5mg
Price
$697
Updated
2024/03/01
Tocris
Product number
2407
Product name
FTI277
Purity
≥95%(HPLC)
Packaging
1
Price
$148
Updated
2021/12/16
Usbiological
Product number
255341
Product name
FTI 277
Packaging
1mg
Price
$389
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0003962
Product name
FTI-277
Purity
95.00%
Packaging
5MG
Price
$501.88
Updated
2021/12/16
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FTI-277 Chemical Properties,Usage,Production

Uses

Farnesyltransferase inhibitor 277 (FTI-277) has been used to:

  • inhibit protein farnesylation in breast cell lines.
  • in marrow-isolated adult multilineage inducible cells (MIAMI).
  • inhibition of farnesyl transferase in CV-1 in Origin with SV40 genes cells (COS-7).

Biochem/physiol Actions

Farnesyltransferase inhibitor 277 (FTI-277) mediates apoptosis in multiple myeloma and is regarded as a potential therapeutic agent.

FTI-277 Preparation Products And Raw materials

Raw materials

Preparation Products

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FTI-277 Suppliers

China 43 Japan 1 Switzerland 1 United Kingdom 4 United States 10 Global 59
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2784
Advantage
58
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2989
Advantage
60
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Shanghai Biopharmaleader Co., Ltd.
Tel
+86 18721201413
Fax
+86 (21) 5775-8967
Email
sales@biopharmaleader.com
Country
China
ProdList
1720
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4662
Advantage
60
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View Lastest Price from FTI-277 manufacturers

Career Henan Chemical Co
Product
FTI-277 trifluoroacetate salt 170006-73-2
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2020-01-09

170006-73-2, FTI-277Related Search:


  • METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA
  • FTI-277
  • N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT
  • N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
  • N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester
  • FTI-277;FTI277
  • L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester
  • 170006-73-2
  • C22H29N3O3S2
  • C22H29N3O3S2C2HF3O2