DisodiuM trans-crocetinate
- Product Name
- DisodiuM trans-crocetinate
- CAS No.
- 591230-99-8
- Chemical Name
- DisodiuM trans-crocetinate
- Synonyms
- Crocetin disodium;Transcrocetinate sodium;Transcrocetinate disodium;DisodiuM trans-crocetinate;Disodium salt of saffron acid;Transcrocetinate disodium, 10 mM in DMSO;Trans Sodium Crocetinate( Disodium trans-crocetinate);Transcrocetinate disodium (Disodium trans-crocetinate);Transcrocetinate disodium (Synonyms: Disodium trans-crocetinate);iGluR,Transcrocetinate disodium,Inhibitor,inhibit,Ionotropic glutamate receptors
- CBNumber
- CB12668641
- Molecular Formula
- C20H25NaO4
- Formula Weight
- 352.41
- MOL File
- 591230-99-8.mol
DisodiuM trans-crocetinate Property
- storage temp.
- Store at -20°C
- solubility
- H2O:16.67(Max Conc. mg/mL);44.77(Max Conc. mM)
- form
- Solid
- color
- Brown to reddish brown
N-Bromosuccinimide Price
- Product number
- CS-0006368
- Product name
- Transcrocetinatedisodium
- Packaging
- 100mg
- Price
- $750
- Updated
- 2021/12/16
- Product number
- orb572893
- Product name
- Transcrocetinate disodium
- Packaging
- 100mg
- Price
- $838.1
- Updated
- 2021/12/16
- Product number
- orb572893
- Product name
- Transcrocetinate disodium
- Packaging
- 250mg
- Price
- $1654.1
- Updated
- 2021/12/16
- Product number
- DC12170
- Product name
- Transcrocetinatedisodium(Disodiumtrans-crocetinate)
- Purity
- >98%
- Packaging
- 1g
- Price
- $2200
- Updated
- 2021/12/16
- Product number
- DC12170
- Product name
- Transcrocetinatedisodium(Disodiumtrans-crocetinate)
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1100
- Updated
- 2021/12/16
DisodiuM trans-crocetinate Chemical Properties,Usage,Production
Uses
Crocetin (Transcrocetin) disodium, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity.
Biological Activity
DisodiuM trans-crocetinate, extracted from saffron (Crocus sativus L.), is a high-affinity NMDA receptor antagonist.
in vitro
Transcrocetinate (Transcrocetin, trans-Crocetin), a saffron metabolite originating from the crocin apocarotenoids, has been shown to exert strong NMDA receptor affinity and is thought to be responsible for the CNS activity of saffron. To ensure unchanged viability of Caco-2 cells throughout the transport experiments, cellular mitochondrial dehydrogenase activity of Caco-2 cells is measured by MTT assay after a 24 h incubation period with the test compounds: Hydroalcoholic saffron extract saffron extract (SE, 0.5-1 mg/mL) and crocin-1 (250-1000 μM) reveal no negative significant changes in cellular viability. Transcrocetinate at 10 μM level does not change viability while higher concentrations (40-160 μM) reduces significantly cellular viability.
< b>
target
NMDA receptor
IC 50
NMDA Receptor
References
[1] Lautenschl?ger M, et al. Intestinal formation of trans-Crocetin from saffron extract (Crocus sativus L.) and in vitro permeation through intestinal and blood brain barrier. Phytomedicine. 2015 Jan 15;22(1):36-44. DOI:10.1016/j.phymed.2014.10.009
DisodiuM trans-crocetinate Preparation Products And Raw materials
Raw materials
Preparation Products
DisodiuM trans-crocetinate Suppliers
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View Lastest Price from DisodiuM trans-crocetinate manufacturers
- Product
- Disodium trans-crocetinate 591230-99-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2024-09-25