8,8'-DIAPOCAROTENEDIOIC ACID

Product Name: 8,8'-DIAPOCAROTENEDIOIC ACID
CAS No.: 27876-94-4
Chemical Name: 8,8'-DIAPOCAROTENEDIOIC ACID
Synonyms: CROCETIN;TRANS-CROCETIN;NSC407300;a-Crocetin;roceic acid;Alpha-Crocetin;Crocetin (6CI);Stable crocetin;trans-Crocetine;CROCETIN, TRANS-
CBNumber: CB5780370
Molecular Formula: C20H24O4
Formula Weight: 328.4
MOL File: 27876-94-4.mol

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8,8'-DIAPOCAROTENEDIOIC ACID Property

Melting point:: 285°
Boiling point:: 386.14°C (rough estimate)
Density: 1.0786 (rough estimate)
refractive index: 1.4434 (estimate)
FEMA: 2998 | SAFFRON (CROCUS SATIVUS L.)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO (Slightly, Heated), Methanol (Slightly)
form: Solid
pka: 4.39±0.19(Predicted)
color: Red to Very Dark Red
Stability:: Light Sensitive
LogP: 4.312 (est)

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Safety

HS Code: 29171900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3255
Product name: Crocetin
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $8.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML3255
Product name: Crocetin
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $43.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL86280
Product name: Crocetin
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $249
Updated: 2024/03/01

Cayman Chemical

Product number: 24217
Product name: Transcrocetin
Purity: ≥98%
Packaging: 5mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 24217
Product name: Transcrocetin
Purity: ≥98%
Packaging: 10mg
Price: $152
Updated: 2024/03/01

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8,8'-DIAPOCAROTENEDIOIC ACID Chemical Properties,Usage,Production

Chemical Properties

Red, rhomboid crystals.Soluble in pyridine and dilute sodium hydroxide; slightly soluble in water and organic solvents. Combustible.

Uses

Experimental treatment of arteriosclerosis by increasing oxygen diffusion through arterial walls, thus decreasing buildup of cholesterol.

Uses

Crocetin is a carotenoid derived from saffron, and is shown to have anticancer effects in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer.

Definition

ChEBI: A 20-carbon dicarboxylic acid which is a diterpenoid and natural carotenoid. Found in the crocus flower, it has been administered as an anti-fatigue dietary supplement.

Anticancer Research

It is a natural apocarotenoid dicarboxylic acid obtained from saffron, and saffron isa spice from the flower of the Saffron crocus and present in the dry stigmas of theplant Crocus sativus which can be used as a food colorant. It is reported to be anovel anticancer agent against hepatocellular carcinoma, pancreatic cancer, lungcancer, skin carcinoma, breast cancer, and colorectal cancer. It inhibits the nucleicacid synthesis, enhances antioxidant system, induces apoptosis, hinders growthfactor signaling pathways, and thus affects the growth of cancer cells. It showseffects in the reduction of LPS-induced nitric oxide release; in the reduction ofproduced IL-1β, TNF-α, and intracellular ROS; in the activation of NF-κB; and inthe blockade of LPS (Wang et al. 2012; Gutheil et al. 2012).

target

COX | NO

8,8'-DIAPOCAROTENEDIOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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8,8'-DIAPOCAROTENEDIOIC ACID Suppliers

China 164 France 1 Germany 1 India 2 South Korea 1 United Kingdom 7 United States 16 Global 192

Sichuan Wei Keqi Biological Technology Co., Ltd.

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ProdList: 7892
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J & K SCIENTIFIC LTD.

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T&W GROUP

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Chengdu Biopurify Phytochemicals Ltd.

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ProdList: 2376
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View Lastest Price from 8,8'-DIAPOCAROTENEDIOIC ACID manufacturers

BINBO BIOLOGICAL CO.,LTD

Product: Crocetin 27876-94-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 75% 98%
Supply Ability: 1000 kg
Release date: 2024-04-26

Shanghai Standard Technology Co., Ltd.

Product: Croceic acid 27876-94-4
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-05-07

Career Henan Chemical Co

Product: 8,8'-DIAPOCAROTENEDIOIC ACID 27876-94-4
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-15

27876-94-4, 8,8'-DIAPOCAROTENEDIOIC ACIDRelated Search:

Lycopene 8,8'-Diapo-ψ,ψ-carotene-8,8'-dioic acid 8-methyl ester Crocin trans-Crocetin (β-D-gentiobiosyl) ester Picrocrocin β-D-Glucopyranose, 1-[hydrogen (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] Dimethylcrocetin 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate]-b-D-Glucopyranose 2,6-DIMETHYL-2,4,6-OCTATRIENE TRANS,TRANS-2,4-HEXADIEN-1-OL 8,8'-DIAPOCAROTENEDIOIC ACID 2,4-HEPTADIEN-1-OL trans,trans-2,4-Heptadienal Sorbic acid trans-2,4-Pentadienoicacid 1-[(2E,4E,6E,8E,10E,12E,14E)-b-D-glucopyranosyl 2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] 6-O-b-D-glucopyranosyl-b-D-Glucopyranose 2,4,6,8-DECATETRAENOIC ACID DECA-2,4,6,8-TETRAENAL

CROCETIN

CROCETIN, TRANS-

8,8'-DIAPOCAROTENEDIOIC ACID

2,6,11,15-TETRAMETHYLHEXADECA-2,4,6,8,10,12,14-HEPTAENEDOIC ACID

TRANS-CROCETIN

8,8'-diapo-psi,psi-carotenedioic acid

Alpha-Crocetin

roceic acid

8,8'-Diapo-ψ,ψ-carotene-8,8'-dioic acid

2,4,6,8,10,12,14-Hexadecaheptaenedioic acid, 2,6,11,15-tetramethyl-, (all-E)- (8CI)

NSC407300

Stable crocetin

Crocetin,trans-Crocetin

Transcrocetin (Synonyms: trans-Crocetin)

(2Z,4E,6Z,8E,10E,12E,14Z)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioic acid

trans-Crocetine

2,4,6,8,10,12,14-Hexadecaheptaenedioic acid, 2,6,11,15-tetramethyl-, (2E,4E,6E,8E,10E,12E,14E)-

TIANFU-8,8'-DIAPOCAROTENEDIOIC ACID

8,8'-Diapo-y,y-carotenedioic acid

a-Crocetin

Crocetin (6CI)

Crocetin(stable)

8,8'-DIAPOCAROTENEDIOIC

8,8'-DIAPOCAROTENEDIOIC ACID

27876-94-4

C20H24O4

Carotenoids