Description Antitumor activity
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Picrocrocin

Description Antitumor activity
Product Name
Picrocrocin
CAS No.
138-55-6
Chemical Name
Picrocrocin
Synonyms
Picrocroin;Picrocrocin;Picrocroine;Safranbitter;Picrocrocine;Saffron-bitter;Picrocrocin USP/EP/BP;Picrocrocin Safranbitter;(R)-4-(β-D-Glucopyranosyloxy)-2,6,6-trimethyl-1-cyclohexene-1-carbaldehyde;(R)-4-(β-D-glucopyranosiloxy)-2,6,6-trimethyl-1-cyclohexene-1-carbaldehyde
CBNumber
CB51236201
Molecular Formula
C16H26O7
Formula Weight
330.37
MOL File
138-55-6.mol
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Picrocrocin Property

Melting point:
196℃ (ethyl acetate )
alpha 
D20 -58° (c = 0.6)
Boiling point:
520.4±50.0 °C(Predicted)
Density 
1.31±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
4°C, protect from light
pka
12.91±0.70(Predicted)
LogP
-0.240 (est)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P437610
Product name
Picrocrocin
Packaging
1mg
Price
$185
Updated
2021/12/16
Biosynth Carbosynth
Product number
MP156887
Product name
Picrocrocin
Packaging
5mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
MP156887
Product name
Picrocrocin
Packaging
10mg
Price
$400
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0003509
Product name
PICROCROCINE
Purity
95.00%
Packaging
5MG
Price
$499.6
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
72034
Product name
Picrocrocin
Packaging
1mg
Price
$675
Updated
2021/12/16
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Picrocrocin Chemical Properties,Usage,Production

Description

Picrocrocin, composing of safranal and glycoside, is one major compounds of saffron (Crocus sativus L. stigma), responsible for the bitter taste of saffron and a molecular marker of this spice, whose taste cannot be imitated from other spices or seasonings, and it can serve to identify true saffron. Saffron possesses various therapeutic activities such as antihypertensive, anticonvulsant, antitussive, antigenototoxic, anticancer, cytotoxic effects, anxiolytic, antioxidant, antidepressant, anti-inflammatory, and relaxant activity. As major bioactive compounds of saffron, picrocrocin also has some valuable medicinal properties similar as saffron, especially anticancer effect.

Antitumor activity

Picrocrocin as component of saffron displays same antitumor activity that have great potential for the prevention and treatment of various cancers through affecting cellular DNA and RNA synthesis and free radical scavenging activities of cancer. The experiments results for studying the effect of picrocrocin on proliferation of human tumoral cells (HeLa cell) in vitro showed that picrocrocin have a dose dependent inhibition of cell growth, and doses of picrocrocin inducing 50% inhibition of HeLa cell growth are 3 mM, in which picrocrocin have minor cytotoxicity for normal cells. Thus, picrocrocin can inhibit the growth of cancer cell. Other study results have showed that picrocrocin with highly bioaccessible could be transported quickly and reduced the proliferation of human adenocarcinoma and hepatocarcinoma cells.

Uses

Picrocrocin is a secondary metabolite of Saffron and has been found to be the taste component of saffron.

Definition

ChEBI: A beta-D-glucoside of beta-cyclocitral; the precursor of safranal. It is the compound most responsible for the bitter taste of saffron.

Picrocrocin Preparation Products And Raw materials

Raw materials

Preparation Products

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Picrocrocin Suppliers

Jiangsu Yongjian Pharmaceutical Technology Co., Ltd
Tel
17701422015
Email
3582572959@qq.com
Country
China
ProdList
697
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Chengdu Herbpurify Co.Ltd.
Tel
18302802153 18981717076
Fax
086-28-85377358
Email
2355253619@qq.com
Country
China
ProdList
1104
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16684
Advantage
50
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
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View Lastest Price from Picrocrocin manufacturers

Career Henan Chemical Co
Product
picrocrocin 138-55-6
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

138-55-6, PicrocrocinRelated Search:


  • Picrocrocin
  • (R)-4-(β-D-glucopyranosiloxy)-2,6,6-trimethyl-1-cyclohexene-1-carbaldehyde
  • (R)-4-(β-D-Glucopyranosyloxy)-2,6,6-trimethyl-1-cyclohexene-1-carbaldehyde
  • Saffron-bitter
  • Picrocrocine
  • 1-Cyclohexene-1-carboxaldehyde,4-(b-D-glucopyranosyloxy)-2,6,6-triMethyl-,(4R)-
  • Safranbitter
  • (4S)-2,6,6-trimethyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-cyclohexene-1-carbaldehyde
  • Picrocrocin Safranbitter
  • 1-Cyclohexene-1-carboxaldehyde, 4-(β-D-glucopyranosyloxy)-2,6,6-trimethyl-, (4R)-
  • Picrocrocin USP/EP/BP
  • Picrocroin
  • Picrocroine
  • (R)-2,6,6-Trimethyl-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)cyclohex-1-ene-1-carbaldehyde
  • 138-55-6
  • C16H26O7