Description Antitumor activity
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Picrocrocin

Description Antitumor activity
Product Name
Picrocrocin
CAS No.
138-55-6
Chemical Name
Picrocrocin
Synonyms
Picrocroin;Picrocrocin;Picrocroine;Safranbitter;Picrocrocine;Saffron-bitter;Picrocrocin USP/EP/BP;Picrocrocin Safranbitter;(R)-4-(β-D-Glucopyranosyloxy)-2,6,6-trimethyl-1-cyclohexene-1-carbaldehyde;(R)-4-(β-D-glucopyranosiloxy)-2,6,6-trimethyl-1-cyclohexene-1-carbaldehyde
CBNumber
CB51236201
Molecular Formula
C16H26O7
Formula Weight
330.37
MOL File
138-55-6.mol
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Picrocrocin Property

Melting point:
196℃ (ethyl acetate )
alpha 
D20 -58° (c = 0.6)
Boiling point:
520.4±50.0 °C(Predicted)
Density 
1.31±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
4°C, protect from light
pka
12.91±0.70(Predicted)
LogP
-0.240 (est)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P437610
Product name
Picrocrocin
Packaging
1mg
Price
$185
Updated
2021/12/16
Biosynth Carbosynth
Product number
MP156887
Product name
Picrocrocin
Packaging
5mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
MP156887
Product name
Picrocrocin
Packaging
10mg
Price
$400
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0003509
Product name
PICROCROCINE
Purity
95.00%
Packaging
5MG
Price
$499.6
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
72034
Product name
Picrocrocin
Packaging
1mg
Price
$675
Updated
2021/12/16
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Picrocrocin Chemical Properties,Usage,Production

Description

Picrocrocin, composing of safranal and glycoside, is one major compounds of saffron (Crocus sativus L. stigma), responsible for the bitter taste of saffron and a molecular marker of this spice, whose taste cannot be imitated from other spices or seasonings, and it can serve to identify true saffron. Saffron possesses various therapeutic activities such as antihypertensive, anticonvulsant, antitussive, antigenototoxic, anticancer, cytotoxic effects, anxiolytic, antioxidant, antidepressant, anti-inflammatory, and relaxant activity. As major bioactive compounds of saffron, picrocrocin also has some valuable medicinal properties similar as saffron, especially anticancer effect.

Antitumor activity

Picrocrocin as component of saffron displays same antitumor activity that have great potential for the prevention and treatment of various cancers through affecting cellular DNA and RNA synthesis and free radical scavenging activities of cancer. The experiments results for studying the effect of picrocrocin on proliferation of human tumoral cells (HeLa cell) in vitro showed that picrocrocin have a dose dependent inhibition of cell growth, and doses of picrocrocin inducing 50% inhibition of HeLa cell growth are 3 mM, in which picrocrocin have minor cytotoxicity for normal cells. Thus, picrocrocin can inhibit the growth of cancer cell. Other study results have showed that picrocrocin with highly bioaccessible could be transported quickly and reduced the proliferation of human adenocarcinoma and hepatocarcinoma cells.

Uses

Picrocrocin is a secondary metabolite of Saffron and has been found to be the taste component of saffron.

Definition

ChEBI: A beta-D-glucoside of beta-cyclocitral; the precursor of safranal. It is the compound most responsible for the bitter taste of saffron.

Picrocrocin Preparation Products And Raw materials

Raw materials

Preparation Products

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Picrocrocin Suppliers

cfm Oskar Tropitzsch
Tel
--
Fax
--
Country
Germany
ProdList
1136
Advantage
62
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View Lastest Price from Picrocrocin manufacturers

Career Henan Chemical Co
Product
picrocrocin 138-55-6
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

138-55-6, PicrocrocinRelated Search:


  • Picrocrocin
  • (R)-4-(β-D-glucopyranosiloxy)-2,6,6-trimethyl-1-cyclohexene-1-carbaldehyde
  • (R)-4-(β-D-Glucopyranosyloxy)-2,6,6-trimethyl-1-cyclohexene-1-carbaldehyde
  • Saffron-bitter
  • Picrocrocine
  • 1-Cyclohexene-1-carboxaldehyde,4-(b-D-glucopyranosyloxy)-2,6,6-triMethyl-,(4R)-
  • Safranbitter
  • (4S)-2,6,6-trimethyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-cyclohexene-1-carbaldehyde
  • Picrocrocin Safranbitter
  • 1-Cyclohexene-1-carboxaldehyde, 4-(β-D-glucopyranosyloxy)-2,6,6-trimethyl-, (4R)-
  • Picrocrocin USP/EP/BP
  • Picrocroin
  • Picrocroine
  • (R)-2,6,6-Trimethyl-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)cyclohex-1-ene-1-carbaldehyde
  • 138-55-6
  • C16H26O7