ChemicalBook > CAS DataBase List > 8,8'-DIAPOCAROTENEDIOIC ACID

8,8'-DIAPOCAROTENEDIOIC ACID

Product Name
8,8'-DIAPOCAROTENEDIOIC ACID
CAS No.
27876-94-4
Chemical Name
8,8'-DIAPOCAROTENEDIOIC ACID
Synonyms
CROCETIN;TRANS-CROCETIN;NSC407300;a-Crocetin;roceic acid;Alpha-Crocetin;Crocetin (6CI);Stable crocetin;trans-Crocetine;CROCETIN, TRANS-
CBNumber
CB5780370
Molecular Formula
C20H24O4
Formula Weight
328.4
MOL File
27876-94-4.mol
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8,8'-DIAPOCAROTENEDIOIC ACID Property

Melting point:
285°
Boiling point:
386.14°C (rough estimate)
Density 
1.0786 (rough estimate)
refractive index 
1.4434 (estimate)
FEMA 
2998 | SAFFRON (CROCUS SATIVUS L.)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
pka
4.39±0.19(Predicted)
color 
Red to Very Dark Red
Stability:
Light Sensitive
LogP
4.312 (est)
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Safety

HS Code 
29171900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3255
Product name
Crocetin
Purity
≥98% (HPLC)
Packaging
5MG
Price
$8.8
Updated
2024/03/01
Sigma-Aldrich
Product number
SML3255
Product name
Crocetin
Purity
≥98% (HPLC)
Packaging
25MG
Price
$43.8
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL86280
Product name
Crocetin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$249
Updated
2024/03/01
Cayman Chemical
Product number
24217
Product name
Transcrocetin
Purity
≥98%
Packaging
5mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
24217
Product name
Transcrocetin
Purity
≥98%
Packaging
10mg
Price
$152
Updated
2024/03/01
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8,8'-DIAPOCAROTENEDIOIC ACID Chemical Properties,Usage,Production

Chemical Properties

Red, rhomboid crystals.Soluble in pyridine and dilute sodium hydroxide; slightly soluble in water and organic solvents. Combustible.

Uses

Experimental treatment of arteriosclerosis by increasing oxygen diffusion through arterial walls, thus decreasing buildup of cholesterol.

Uses

Crocetin is a carotenoid derived from saffron, and is shown to have anticancer effects in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer.

Definition

ChEBI: A 20-carbon dicarboxylic acid which is a diterpenoid and natural carotenoid. Found in the crocus flower, it has been administered as an anti-fatigue dietary supplement.

Anticancer Research

It is a natural apocarotenoid dicarboxylic acid obtained from saffron, and saffron isa spice from the flower of the Saffron crocus and present in the dry stigmas of theplant Crocus sativus which can be used as a food colorant. It is reported to be anovel anticancer agent against hepatocellular carcinoma, pancreatic cancer, lungcancer, skin carcinoma, breast cancer, and colorectal cancer. It inhibits the nucleicacid synthesis, enhances antioxidant system, induces apoptosis, hinders growthfactor signaling pathways, and thus affects the growth of cancer cells. It showseffects in the reduction of LPS-induced nitric oxide release; in the reduction ofproduced IL-1β, TNF-α, and intracellular ROS; in the activation of NF-κB; and inthe blockade of LPS (Wang et al. 2012; Gutheil et al. 2012).

target

COX | NO

8,8'-DIAPOCAROTENEDIOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 8,8'-DIAPOCAROTENEDIOIC ACID manufacturers

BINBO BIOLOGICAL CO.,LTD
Product
Crocetin 27876-94-4
Price
US $0.00/kg
Min. Order
1kg
Purity
75% 98%
Supply Ability
1000 kg
Release date
2024-04-26
Shanghai Standard Technology Co., Ltd.
Product
Croceic acid 27876-94-4
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-05-07
Career Henan Chemical Co
Product
8,8'-DIAPOCAROTENEDIOIC ACID 27876-94-4
Price
US $1.00/KG
Min. Order
1G
Purity
98%
Supply Ability
100KG
Release date
2018-08-15

27876-94-4, 8,8'-DIAPOCAROTENEDIOIC ACIDRelated Search:

Lycopene 8,8'-Diapo-ψ,ψ-carotene-8,8'-dioic acid 8-methyl ester Crocin trans-Crocetin (β-D-gentiobiosyl) ester Picrocrocin β-D-Glucopyranose, 1-[hydrogen (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] Dimethylcrocetin 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate]-b-D-Glucopyranose 2,6-DIMETHYL-2,4,6-OCTATRIENE TRANS,TRANS-2,4-HEXADIEN-1-OL 8,8'-DIAPOCAROTENEDIOIC ACID 2,4-HEPTADIEN-1-OL trans,trans-2,4-Heptadienal Sorbic acid trans-2,4-Pentadienoicacid 1-[(2E,4E,6E,8E,10E,12E,14E)-b-D-glucopyranosyl 2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] 6-O-b-D-glucopyranosyl-b-D-Glucopyranose 2,4,6,8-DECATETRAENOIC ACID DECA-2,4,6,8-TETRAENAL

  • CROCETIN
  • CROCETIN, TRANS-
  • 8,8'-DIAPOCAROTENEDIOIC ACID
  • 2,6,11,15-TETRAMETHYLHEXADECA-2,4,6,8,10,12,14-HEPTAENEDOIC ACID
  • TRANS-CROCETIN
  • 8,8'-diapo-psi,psi-carotenedioic acid
  • Alpha-Crocetin
  • roceic acid
  • 8,8'-Diapo-ψ,ψ-carotene-8,8'-dioic acid
  • 2,4,6,8,10,12,14-Hexadecaheptaenedioic acid, 2,6,11,15-tetramethyl-, (all-E)- (8CI)
  • NSC407300
  • Stable crocetin
  • Crocetin,trans-Crocetin
  • Transcrocetin (Synonyms: trans-Crocetin)
  • (2Z,4E,6Z,8E,10E,12E,14Z)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioic acid
  • trans-Crocetine
  • 2,4,6,8,10,12,14-Hexadecaheptaenedioic acid, 2,6,11,15-tetramethyl-, (2E,4E,6E,8E,10E,12E,14E)-
  • TIANFU-8,8'-DIAPOCAROTENEDIOIC ACID
  • 8,8'-Diapo-y,y-carotenedioic acid
  • a-Crocetin
  • Crocetin (6CI)
  • Crocetin(stable)
  • 8,8'-DIAPOCAROTENEDIOIC
  • 8,8'-DIAPOCAROTENEDIOIC ACID
  • 27876-94-4
  • C20H24O4
  • Carotenoids