Rosuvastatin IMpurity SodiuM Salt (5-Oxo Rosuvastatin SodiuM Salt) Property

Boiling point:

731.0±70.0 °C(Predicted)

Density 

1.365±0.06 g/cm3(Predicted)

solubility 

Chloroform (Slightly), DMSO (Sparingly), Methanol (Sparingly)

pka

4.17±0.10(Predicted)

form 

Solid

color 

Pale Yellow to Very Dark Beige

Stability:

Hygroscopic

InChIKey

SGVASDMKSZUTTN-OAGJVSPASA-N

SMILES

C(O)(=O)C[C@H](O)CC(=O)/C=C/C1=C(C(C)C)N=C(N(C)S(C)(=O)=O)N=C1C1=CC=C(F)C=C1

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Rosuvastatin IMpurity SodiuM Salt (5-Oxo Rosuvastatin SodiuM Salt) Chemical Properties,Usage,Production

Uses

5-Oxo Rosuvastatin (Rosuvastatin EP Impurity C (Calcium Salt)) is a Rosuvastatin (R700500) impurity.

Application

5-Oxo Rosuvastatin (Rosuvastatin EP Impurity C (Calcium Salt)) is a Rosuvastatin impurity. It can be used as a reference substance to analyze the quality of drugs and is often used in the pharmaceutical industry. Rosuvastatin is used together with a proper diet to lower bad cholesterol (LDL) and triglycerides (fats) in the blood and to increase good cholesterol (HDL). It is also used to treat adults who cannot control their cholesterol levels by diet and exercise alone. It may help prevent or slow down medical problems, like atherosclerosis (hardening of the arteries), that are caused by fats clogging the blood vessels. It may also be used to prevent certain types of heart and blood vessel problems in patients with risk factors for heart problems.