5-chloro-2,3-diphenylpyrazine
- Product Name
- 5-chloro-2,3-diphenylpyrazine
- CAS No.
- 41270-66-0
- Chemical Name
- 5-chloro-2,3-diphenylpyrazine
- Synonyms
- Selexipag Impurity 31;2-Chloro-5,6-diphenylpyrazine;Pyrazine, 5-chloro-2,3-diphenyl-;5-chlChemicalbookoro-2,3-diphenylpyrazine;chloro-2,3-diphenylpyrazine (Selexipag Intermediate)
- CBNumber
- CB12676877
- Molecular Formula
- C16H11ClN2
- Formula Weight
- 266.72
- MOL File
- 41270-66-0.mol
5-chloro-2,3-diphenylpyrazine Property
- Melting point:
- 126-128℃ (methanol )
- Boiling point:
- 145°C/0.001mmHg(lit.)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- pka
- -2.16±0.10(Predicted)
- form
- powder to crystal
- color
- White to Orange to Green
- InChI
- InChI=1S/C16H11ClN2/c17-14-11-18-15(12-7-3-1-4-8-12)16(19-14)13-9-5-2-6-10-13/h1-11H
- InChIKey
- VUGNCPVAXWZTOL-UHFFFAOYSA-N
- SMILES
- C1(C2=CC=CC=C2)=NC=C(Cl)N=C1C1=CC=CC=C1
- CAS DataBase Reference
- 41270-66-0
Safety
- HS Code
- 2933.99.5300
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C3205
- Product name
- 5-Chloro-2,3-diphenylpyrazine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $88
- Updated
- 2024/03/01
- Product number
- C3205
- Product name
- 5-Chloro-2,3-diphenylpyrazine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $439
- Updated
- 2024/03/01
- Product number
- C365848
- Product name
- 2-Chloro-5,6-diphenylpyrazine
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- C365848
- Product name
- 2-Chloro-5,6-diphenylpyrazine
- Packaging
- 1g
- Price
- $105
- Updated
- 2021/12/16
- Product number
- 5680AB
- Product name
- 5-Chloro-2,3-diphenylpyrazine
- Packaging
- 5g
- Price
- $273
- Updated
- 2021/12/16
5-chloro-2,3-diphenylpyrazine Chemical Properties,Usage,Production
Uses
2-Chloro-5,6-diphenylpyrazine is a diphenylpyrazine derivative used in a study to determine a novel class of prostacyclin receptor agonists.
Synthesis
50 gm of 2-hydroxy-5,6-diphenylpyrazine obtained was treated with 250 ml of POCI3 and then heated the reaction mixture at 100-110 °C with stirring for 5-6 hrs. The reaction mixture was cooled to room temperature and poured in 1000 ml of ice water at 0-5 °C and maintained with stirring for 60 minutes. The solid obtained was filtered, washed with water and dried to obtain 41.3 gm of 5-chloro-2,3-diphenylpyrazine. Yield: 77.00 percent.
5-chloro-2,3-diphenylpyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
5-chloro-2,3-diphenylpyrazine Suppliers
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- Country
- India
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- 6768
- Advantage
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- India
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View Lastest Price from 5-chloro-2,3-diphenylpyrazine manufacturers
- Product
- 5-chloro-2,3-diphenylpyrazine 41270-66-0
- Price
- US $8.00-2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-24
- Product
- 5-chloro-2,3-diphenylpyrazine 41270-66-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-31
- Product
- 5-chloro-2,3-diphenylpyrazine 41270-66-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.1kg
- Purity
- 99.0%min
- Supply Ability
- 2000kg
- Release date
- 2023-06-09