SELEXIPAG interMediate

Product Name: SELEXIPAG interMediate
CAS No.: 475086-75-0
Chemical Name: SELEXIPAG interMediate
Synonyms: 4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol;SELEXIPAH INT;Selexipag internate 1;Selexipag Impurity 32;SELEXIPAG interMediate;Selexipag intermediates;Diphenyl pyrazine impurity;4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol;4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol;-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol
CBNumber: CB42728841
Molecular Formula: C23H27N3O
Formula Weight: 361.48
MOL File: 475086-75-0.mol

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SELEXIPAG interMediate Property

Melting point:: 68 - 71°C
Boiling point:: 514.4±50.0 °C(Predicted)
Density: 1.112±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), DMSO (Slightly)
pka: 15.05±0.10(Predicted)
form: Solid
color: Pale Yellow to Light Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-M3070
Product name: 1-Butanol,4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]-
Packaging: 1g
Price: $100
Updated: 2021/12/16

Ambeed

Product number: A822980
Product name: 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
Purity: 98%
Packaging: 1g
Price: $112
Updated: 2021/12/16

Chemenu

Product number: CM101916
Product name: 4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol
Purity: 95%+
Packaging: 1g
Price: $182
Updated: 2021/12/16

Crysdot

Product number: CD11120258
Product name: 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
Purity: 97%
Packaging: 1g
Price: $200
Updated: 2021/12/16

Ambeed

Product number: A822980
Product name: 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
Purity: 98%
Packaging: 5g
Price: $311
Updated: 2021/12/16

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SELEXIPAG interMediate Chemical Properties,Usage,Production

Uses

4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.

Application

Selexipag interMediate is a synthetic organic compound that is used as an intermediate in the synthesis of oxychloride. It is an oxychloride with a nucleophilic substitution reaction. The reaction proceeds selectively at the phosphorus atom and gives high yield. The reactivity of 4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butan-1-ol is enhanced by the use of n butanol, which also acts as a solvent for the reaction. The product can be purified by filtration or recrystallization from hexane with piperazine as a reagent.

SELEXIPAG interMediate Preparation Products And Raw materials

Raw materials

Preparation Products

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SELEXIPAG interMediate Suppliers

China 107 India 6 Global 113

Nanjing CoreTech Biomedical Co,.Ltd

Tel: 025-52880806 13770327895
Fax: 86-025-52880803
Email: API@core-tech.com.cn
Country: China
ProdList: 82
Advantage: 58

EASON Chemical Co., LIMITED

Tel: 0576-0576-89232655 13566878689
Fax: 0576-88860891
Email: info@seasonsbio.com
Country: China
ProdList: 39
Advantage: 58

Nanjing Puxin Pharmaceutical Technology Co., Ltd

Tel: 17366295326
Fax: QQ360829978
Email: puxinpharma_2017@126.com
Country: China
ProdList: 2435
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7583
Advantage: 55

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 6854
Advantage: 65

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 4974
Advantage: 50

SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.

Tel: 021-34666753 13311639313
Fax: +86-21-34979012
Email: info@shyrchem.com
Country: China
ProdList: 570
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

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View Lastest Price from SELEXIPAG interMediate manufacturers

Henan Fengda Chemical Co., Ltd

Product: SELEXIPAG interMediate 475086-75-0
Price: US $35.00-0.90/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-22

Career Henan Chemical Co

Product: SELEXIPAG interMediate 475086-75-0
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2018-08-15

475086-75-0, SELEXIPAG interMediateRelated Search:

5-chloro-2,3-diphenylpyrazine ( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester ) [4-[(5,6-DIPHENYLPYRAZINYL)(1-METHYLETHYL)AMINO]BUTOXY]-ACETIC ACID 2,3-DIPHENYLPYRAZINE Bromoacetic acid 2-T-BUTYL GLYCOLATE 4-(Isopropylamino)butanol 5,6-DIPHENYLPYRAZIN-2-OL N-(methylsulfonyl)glycine 2,3-Dichloro-5,6-diphenylpyrazine Cefepime Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]- 2-Pyrazinamine, N-(1-methylethyl)-5,6-diphenyl- 1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)oxy]- Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]-, 1,1-dimethylethyl ester Acetamide, 2-[4-[(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)- Acetamide, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-

SELEXIPAG interMediate

4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol

Selexipag intermediates

1-Butanol, 4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]-

1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-

4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol

-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol

4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol

Selexipag Impurity 32

SELEXIPAH INT

Selexipag internate 1

Selexipag Impurity AQ: What is Selexipag Impurity A Q: What is the CAS Number of Selexipag Impurity A Q: What is the storage condition of Selexipag Impurity A Q: What are the applications of Selexipag Impurity A

Diphenyl pyrazine impurity

4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol (Isopropylamine Impurity)

475086-75-0

selexipag

non-prostanoid prostacyclin (PGI2) receptor agonist