SELEXIPAG interMediate

Product Name: SELEXIPAG interMediate
CAS No.: 475086-75-0
Chemical Name: SELEXIPAG interMediate
Synonyms: 4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol;SELEXIPAH INT;Selexipag internate 1;Selexipag Impurity 32;SELEXIPAG interMediate;Selexipag intermediates;Diphenyl pyrazine impurity;4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol;4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol;-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol
CBNumber: CB42728841
Molecular Formula: C23H27N3O
Formula Weight: 361.48
MOL File: 475086-75-0.mol

More

Less

SELEXIPAG interMediate Property

Melting point:: 68 - 71°C
Boiling point:: 514.4±50.0 °C(Predicted)
Density: 1.112±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), DMSO (Slightly)
pka: 15.05±0.10(Predicted)
form: Solid
color: Pale Yellow to Light Yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-M3070
Product name: 1-Butanol,4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]-
Packaging: 1g
Price: $100
Updated: 2021/12/16

Ambeed

Product number: A822980
Product name: 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
Purity: 98%
Packaging: 1g
Price: $112
Updated: 2021/12/16

Chemenu

Product number: CM101916
Product name: 4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol
Purity: 95%+
Packaging: 1g
Price: $182
Updated: 2021/12/16

Crysdot

Product number: CD11120258
Product name: 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
Purity: 97%
Packaging: 1g
Price: $200
Updated: 2021/12/16

Ambeed

Product number: A822980
Product name: 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
Purity: 98%
Packaging: 5g
Price: $311
Updated: 2021/12/16

More

Less

SELEXIPAG interMediate Chemical Properties,Usage,Production

Uses

4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.

Application

Selexipag interMediate is a synthetic organic compound that is used as an intermediate in the synthesis of oxychloride. It is an oxychloride with a nucleophilic substitution reaction. The reaction proceeds selectively at the phosphorus atom and gives high yield. The reactivity of 4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butan-1-ol is enhanced by the use of n butanol, which also acts as a solvent for the reaction. The product can be purified by filtration or recrystallization from hexane with piperazine as a reagent.

SELEXIPAG interMediate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

SELEXIPAG interMediate Suppliers

China 115 India 6 Global 121

Nanjing CoreTech Biomedical Co,.Ltd

Tel: 025-52880806 13770327895
Fax: 86-025-52880803
Email: API@core-tech.com.cn
Country: China
ProdList: 84
Advantage: 58

EASON Chemical Co., LIMITED

Tel: 0576-0576-89232655 13566878689
Fax: 0576-88860891
Email: info@seasonsbio.com
Country: China
ProdList: 37
Advantage: 58

Nanjing Puxin Pharmaceutical Technology Co., Ltd

Tel: 17366295326
Fax: QQ360829978
Email: puxinpharma_2017@126.com
Country: China
ProdList: 2444
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8418
Advantage: 55

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7191
Advantage: 65

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5047
Advantage: 50

SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.

Tel: 021-34666753 13311639313
Fax: +86-21-34979012
Email: info@shyrchem.com
Country: China
ProdList: 571
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

More

Less

View Lastest Price from SELEXIPAG interMediate manufacturers

Henan Fengda Chemical Co., Ltd

Product: SELEXIPAG interMediate 475086-75-0
Price: US $35.00-0.90/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-22

Career Henan Chemical Co

Product: SELEXIPAG interMediate 475086-75-0
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2018-08-15

475086-75-0, SELEXIPAG interMediateRelated Search:

5-chloro-2,3-diphenylpyrazine ( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester ) [4-[(5,6-DIPHENYLPYRAZINYL)(1-METHYLETHYL)AMINO]BUTOXY]-ACETIC ACID 2,3-DIPHENYLPYRAZINE Bromoacetic acid 2-T-BUTYL GLYCOLATE 4-(Isopropylamino)butanol 5,6-DIPHENYLPYRAZIN-2-OL N-(methylsulfonyl)glycine 2,3-Dichloro-5,6-diphenylpyrazine Cefepime Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]- 2-Pyrazinamine, N-(1-methylethyl)-5,6-diphenyl- 1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)oxy]- Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]-, 1,1-dimethylethyl ester Acetamide, 2-[4-[(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)- Acetamide, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-

SELEXIPAG interMediate

4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol

Selexipag intermediates

1-Butanol, 4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]-

1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-

4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol

-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol

4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol

Selexipag Impurity 32

SELEXIPAH INT

Selexipag internate 1

Selexipag Impurity AQ: What is Selexipag Impurity A Q: What is the CAS Number of Selexipag Impurity A Q: What is the storage condition of Selexipag Impurity A Q: What are the applications of Selexipag Impurity A

4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol (Isopropylamine Impurity)

4-[(5,6-Diphenylpyrazin-2-yl)(1-methylethyl)amino]-1-butanol

Diphenyl pyrazine impurity

475086-75-0

selexipag

non-prostanoid prostacyclin (PGI2) receptor agonist