ChemicalBook > CAS DataBase List > SELEXIPAG interMediate

SELEXIPAG interMediate

Product Name
SELEXIPAG interMediate
CAS No.
475086-75-0
Chemical Name
SELEXIPAG interMediate
Synonyms
4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol;SELEXIPAH INT;Selexipag internate 1;Selexipag Impurity 32;SELEXIPAG interMediate;Selexipag intermediates;Diphenyl pyrazine impurity;4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol;4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol;-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol
CBNumber
CB42728841
Molecular Formula
C23H27N3O
Formula Weight
361.48
MOL File
475086-75-0.mol
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SELEXIPAG interMediate Property

Melting point:
68 - 71°C
Boiling point:
514.4±50.0 °C(Predicted)
Density 
1.112±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly)
pka
15.05±0.10(Predicted)
form 
Solid
color 
Pale Yellow to Light Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-M3070
Product name
1-Butanol,4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]-
Packaging
1g
Price
$100
Updated
2021/12/16
Ambeed
Product number
A822980
Product name
4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
Purity
98%
Packaging
1g
Price
$112
Updated
2021/12/16
Chemenu
Product number
CM101916
Product name
4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol
Purity
95%+
Packaging
1g
Price
$182
Updated
2021/12/16
Crysdot
Product number
CD11120258
Product name
4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
Purity
97%
Packaging
1g
Price
$200
Updated
2021/12/16
Ambeed
Product number
A822980
Product name
4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
Purity
98%
Packaging
5g
Price
$311
Updated
2021/12/16
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SELEXIPAG interMediate Chemical Properties,Usage,Production

Uses

4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.

Application

Selexipag interMediate is a synthetic organic compound that is used as an intermediate in the synthesis of oxychloride. It is an oxychloride with a nucleophilic substitution reaction. The reaction proceeds selectively at the phosphorus atom and gives high yield. The reactivity of 4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butan-1-ol is enhanced by the use of n butanol, which also acts as a solvent for the reaction. The product can be purified by filtration or recrystallization from hexane with piperazine as a reagent.

SELEXIPAG interMediate Preparation Products And Raw materials

Raw materials

Preparation Products

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SELEXIPAG interMediate Suppliers

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View Lastest Price from SELEXIPAG interMediate manufacturers

Henan Fengda Chemical Co., Ltd
Product
SELEXIPAG interMediate 475086-75-0
Price
US $35.00-0.90/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-22
Career Henan Chemical Co
Product
SELEXIPAG interMediate 475086-75-0
Price
US $2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2018-08-15

475086-75-0, SELEXIPAG interMediateRelated Search:

5-chloro-2,3-diphenylpyrazine ( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester ) [4-[(5,6-DIPHENYLPYRAZINYL)(1-METHYLETHYL)AMINO]BUTOXY]-ACETIC ACID 2,3-DIPHENYLPYRAZINE Bromoacetic acid 2-T-BUTYL GLYCOLATE 4-(Isopropylamino)butanol 5,6-DIPHENYLPYRAZIN-2-OL N-(methylsulfonyl)glycine 2,3-Dichloro-5,6-diphenylpyrazine Cefepime Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]- 2-Pyrazinamine, N-(1-methylethyl)-5,6-diphenyl- 1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)oxy]- Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]-, 1,1-dimethylethyl ester Acetamide, 2-[4-[(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)- Acetamide, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-

  • SELEXIPAG interMediate
  • 4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol
  • Selexipag intermediates
  • 1-Butanol, 4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]-
  • 1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-
  • 4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol
  • -[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol
  • 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
  • Selexipag Impurity 32
  • SELEXIPAH INT
  • Selexipag internate 1
  • Selexipag Impurity AQ: What is Selexipag Impurity A Q: What is the CAS Number of Selexipag Impurity A Q: What is the storage condition of Selexipag Impurity A Q: What are the applications of Selexipag Impurity A
  • Diphenyl pyrazine impurity
  • 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol (Isopropylamine Impurity)
  • 475086-75-0
  • selexipag
  • non-prostanoid prostacyclin (PGI2) receptor agonist