SELEXIPAG interMediate
- Product Name
- SELEXIPAG interMediate
- CAS No.
- 475086-75-0
- Chemical Name
- SELEXIPAG interMediate
- Synonyms
- 4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol;SELEXIPAH INT;Selexipag internate 1;Selexipag Impurity 32;SELEXIPAG interMediate;Selexipag intermediates;Diphenyl pyrazine impurity;4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol;4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol;-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol
- CBNumber
- CB42728841
- Molecular Formula
- C23H27N3O
- Formula Weight
- 361.48
- MOL File
- 475086-75-0.mol
SELEXIPAG interMediate Property
- Melting point:
- 68 - 71°C
- Boiling point:
- 514.4±50.0 °C(Predicted)
- Density
- 1.112±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), DMSO (Slightly)
- pka
- 15.05±0.10(Predicted)
- form
- Solid
- color
- Pale Yellow to Light Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-M3070
- Product name
- 1-Butanol,4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]-
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- A822980
- Product name
- 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
- Purity
- 98%
- Packaging
- 1g
- Price
- $112
- Updated
- 2021/12/16
- Product number
- CM101916
- Product name
- 4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol
- Purity
- 95%+
- Packaging
- 1g
- Price
- $182
- Updated
- 2021/12/16
- Product number
- CD11120258
- Product name
- 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
- Purity
- 97%
- Packaging
- 1g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- A822980
- Product name
- 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
- Purity
- 98%
- Packaging
- 5g
- Price
- $311
- Updated
- 2021/12/16
SELEXIPAG interMediate Chemical Properties,Usage,Production
Uses
4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.
Application
Selexipag interMediate is a synthetic organic compound that is used as an intermediate in the synthesis of oxychloride. It is an oxychloride with a nucleophilic substitution reaction. The reaction proceeds selectively at the phosphorus atom and gives high yield. The reactivity of 4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butan-1-ol is enhanced by the use of n butanol, which also acts as a solvent for the reaction. The product can be purified by filtration or recrystallization from hexane with piperazine as a reagent.
SELEXIPAG interMediate Preparation Products And Raw materials
Raw materials
Preparation Products
SELEXIPAG interMediate Suppliers
View Lastest Price from SELEXIPAG interMediate manufacturers
- Product
- SELEXIPAG interMediate 475086-75-0
- Price
- US $35.00-0.90/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-22
- Product
- SELEXIPAG interMediate 475086-75-0
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2018-08-15