MLS-0315848 hydrochloride

Product Name: MLS-0315848 hydrochloride
CAS No.: 1135318-57-8
Chemical Name: MLS-0315848 hydrochloride
Synonyms: ML095;ML095 HCL;MLS-0315848 hcl;ML095 hydrochloride;MLS-0315848 hydrochloride;CID-25067483 hydrochloride;ML-095 hydrochloride, 10 mM in DMSO;1-(3,4-dihydroxyphenyl)-2-(2-ethylimidazol-1-yl)ethanone;1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanone Hydrochloride;1-(3,4-Dihydroxyphenyl)-2-(2-ethyl-1H-imidazol-1-yl)-Ethanone hydrochloride
CBNumber: CB12750702
Molecular Formula: C13H15ClN2O3
Formula Weight: 282.72
MOL File: 1135318-57-8.mol

More

Less

MLS-0315848 hydrochloride Property

storage temp.: 2-8°C
solubility: H2O: soluble5mg/mL, clear
form: powder
color: white to beige

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 15173
Product name: ML-095 (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 15173
Product name: ML-095 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $118
Updated: 2024/03/01

Cayman Chemical

Product number: 15173
Product name: ML-095 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $193
Updated: 2024/03/01

Cayman Chemical

Product number: 15173
Product name: ML-095 (hydrochloride)
Purity: ≥98%
Packaging: 25mg
Price: $374
Updated: 2024/03/01

TRC

Product number: D454515
Product name: 1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanoneHydrochloride
Packaging: 1mg
Price: $50
Updated: 2021/12/16

More

Less

MLS-0315848 hydrochloride Chemical Properties,Usage,Production

Uses

1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanone Hydrochloride is a biochemical inhibitor of placental alkaline phosphatase (PLAP) and is used to elucidate the key biological functions and natural substrates of human PLAP.

Biological Activity

ml-095 (hydrochloride) is a specific plap inhibitor [1].alkaline phosphatases are hydrolase enzymes responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. there are three isozymes of alkaline phosphatases: placental alkaline phosphatase (plap), intestinal alkaline phosphatase (iap), and tissue non-specific alkaline phosphatase (tnap). placental alkaline phosphatase (plap) is highly expressed in primate placental tissue and the biological function is still unknown. however, plap-like enzymes are detected in serum of patients with primary testicular tumors, in particular seminoma and other cancers [1].ml-095 (cid-25067483) is a biochemical inhibitor of plap and will be useful to elucidate the key biological functions and natural substrates of human plap. ml095 is a specific plap inhibitor and inhibited plap, tnap and iap with ic50 values of 2.1, >100 and 53 μm, respectively. ml095 exhibited greater than 25-fold selectivity over tissue non-specific alkaline phosphatase (tnap) and intestinal alkaline phosphatase (iap) [1].

References

[1]. lanier m, cashman j, sergienko e, et al. placental alkaline phosphatase (plap) luminescent hts assay - probe 2.

MLS-0315848 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

MLS-0315848 hydrochloride Suppliers

China 30 India 1 United States 6 Global 37

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

1135318-57-8, MLS-0315848 hydrochlorideRelated Search:

1-(3,4-Dihydroxyphenyl)-2-(2-ethyl-1H-imidazol-1-yl)-Ethanone hydrochloride

CID-25067483 hydrochloride

ML095 hydrochloride

MLS-0315848 hydrochloride

1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanone Hydrochloride

MLS-0315848 hcl

ML095 HCL

CID-25067483,ML-095,ML 095,ML095 hydrochloride,ML095,inhibit,ML 095 hydrochloride,CID25067483,Inhibitor,CID 25067483

ML095

1-(3,4-dihydroxyphenyl)-2-(2-ethylimidazol-1-yl)ethanone

ML-095 hydrochloride, 10 mM in DMSO

1135318-57-8

C13H14N2O3HCl