ChemicalBook > CAS DataBase List > TAUROCHENODEOXYCHOLIC ACID SODIUM SALT

TAUROCHENODEOXYCHOLIC ACID SODIUM SALT

Product Name
TAUROCHENODEOXYCHOLIC ACID SODIUM SALT
CAS No.
6009-98-9
Chemical Name
TAUROCHENODEOXYCHOLIC ACID SODIUM SALT
Synonyms
NSC681055;Ursodeoxycholic Impurity 15;SODIUM TAUROCHENODEOXYCHOLATE;Chenodeoxycholic Acid Impurity;TAUROCHENODEOXYCHOLIC ACID SODIUM;SODIUM TAUROCHENODEOXYCHOLIC ACID;Urosodeoxycholic Acid Impurity 15;Taurine goose deoxycholate sodium;Aurochenodeoxycholic acid sodiuM salt;taurochenodeoxycholic acid soduim salt
CBNumber
CB1277818
Molecular Formula
C26H44NNaO6S
Formula Weight
521.69
MOL File
6009-98-9.mol
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TAUROCHENODEOXYCHOLIC ACID SODIUM SALT Property

Melting point:
165-175 °C
storage temp. 
room temp
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
BRN 
3901205
Stability:
Hygroscopic
InChIKey
IYPNVUSIMGAJFC-UKYQSIPTNA-M
CAS DataBase Reference
6009-98-9(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
3-10
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T6260
Product name
Sodium taurochenodeoxycholate
Packaging
100mg
Price
$221
Updated
2025/07/31
Sigma-Aldrich
Product number
T6260
Product name
Sodium taurochenodeoxycholate
Packaging
1g
Price
$1000
Updated
2025/07/31
Cayman Chemical
Product number
20275
Product name
Taurochenodeoxycholic Acid (sodium salt)
Purity
≥95%
Packaging
50mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
20275
Product name
Taurochenodeoxycholic Acid (sodium salt)
Purity
≥95%
Packaging
100mg
Price
$115
Updated
2024/03/01
Sigma-Aldrich
Product number
T6260
Product name
Sodium taurochenodeoxycholate
Packaging
250mg
Price
$488.99
Updated
2025/07/31
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TAUROCHENODEOXYCHOLIC ACID SODIUM SALT Chemical Properties,Usage,Production

Description

Taurochenodeoxycholic acid (TCDCA) is a taurine-conjugated form of the primary bile acid chenodeoxycholic acid (CDCA; ). Serum levels of TCDCA increase approximately 5-fold in within two hours and begin to decrease within four hours during an oral lipid tolerance test in humans. Serum levels of TCDCA are increased in patients with liver cirrhosis and may serve as a marker of disease progression.

Chemical Properties

Solid

Uses

Labeled Taurochenodeoxycholic Acid, intended for use as an internal standard for the quantification of Taurochenodeoxycholic Acid by GC- or LC-mass spectrometry.

Uses

Taurochenodeoxycholic Acid Sodium Salt is a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.

General Description

An ionic detergent used for solubilizing lipids and proteins.

in vivo

Taurochenodeoxycholic acid (12-Deoxycholyltaurine; TCDCA; 0.05, 0.1g/kg) sodium decreases the pulmonary coefficient in the model mice and reduces the pathological damages on their lungs; it can decrease the expression levels of TNF-α and TIMP-2 in pulmonary tissues in the pulmonary fibrosis mice and has no significant effects on MMP2[2].
Taurochenodeoxycholic acid sodium significantly normalizes the clinical inflammatory parameters, prevented indomethacin-induced increases in the biliary contents of secondary bile acids and hydrophobicity index, and tended to attenuate the intestinal inflammation[3].
Taurochenodeoxycholic acid sodium significantly suppresses paw swelling and polyarthritis index, increases the loss body weight and index of thymus and spleen, and amends radiologic changes in AA rats. The overproduction and mRNA expression of TNF-α, IL-1β and IL-6 are remarkably suppressed in serum and synovium tissue of all TCDCA-treated rats[4].

IC 50

Microbial Metabolite; Human Endogenous Metabolite

References

[1] HOFMANN A F. The continuing importance of bile acids in liver and intestinal disease.[J]. Archives of internal medicine, 1999, 159 22: 2647-2658. DOI: 10.1001/archinte.159.22.2647
[2] A. SCHMID. Bile Acid Metabolome after an Oral Lipid Tolerance Test by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)[J]. PLoS ONE, 2016, 11 1. DOI: 10.1371/journal.pone.0148869
[3] XIAONING WANG. Serum Bile Acids Are Associated with Pathological Progression of Hepatitis B-Induced Cirrhosis[J]. Journal of Proteome Research, 2015, 15 4: 1126-1134. DOI: 10.1021/acs.jproteome.5b00217

TAUROCHENODEOXYCHOLIC ACID SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from TAUROCHENODEOXYCHOLIC ACID SODIUM SALT manufacturers

Anhuyan (Hainan) Biotechnology Co., LTD
Product
TAUROCHENODEOXYCHOLIC ACID SODIUM SALT 6009-98-9
Price
US $3.00/g
Min. Order
1g
Purity
99.99
Supply Ability
1000000
Release date
2025-06-05
Shaanxi Xianhe Biotech Co., Ltd
Product
taurocholate 6009-98-9
Price
US $0.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
1000KG
Release date
2025-04-18
R&D Scientific Inc.
Product
Tauroursodeoxycholate Sodium 6009-98-9
Price
US $1890.00/g
Min. Order
1g
Purity
97
Supply Ability
500 Kg
Release date
2024-05-07

6009-98-9, TAUROCHENODEOXYCHOLIC ACID SODIUM SALTRelated Search:


  • Sodium taurochenodeoxycholate,2-([3α,7α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt, 3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt, Taurochenodeoxy
  • taurochenodeoxycholic acid soduim salt
  • 3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt
  • Taurochenodeoxycholic Acid D4 Sodium Salt
  • 2-([3-ALPHA,7-ALPHA-DIHYDROXY-24-OXO-5-BETA-CHOLAN-24-YL]AMINO)ETHANESULFONIC ACID
  • 2-[(3ALPHA,7ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)AMINO]ETHANESULFONIC ACID SODIUM SALT
  • 5-BETA-CHOLANIC ACID-3-ALPHA, 7-ALPHA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
  • 5BETA-CHOLANIC ACID-3ALPHA,7ALPHA-DIOL-24-N-(2-SULFOETHYL)-AMIDE SODIUM
  • 5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE-3ALPHA,7ALPHA-DIOL SODIUM SALT
  • 3ALPHA,7ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE SODIUM SALT
  • TAUROCHENODESOXYCHOLIC ACID, SODIUM SALT
  • Ursodeoxycholic Impurity 15
  • TAUROCHENODEOXYCHOLIC ACID SODIUM
  • TAUROCHENODEOXYCHOLIC ACID SODIUM SALT
  • SODIUM TAUROCHENODEOXYCHOLATE
  • SODIUM TAUROCHENODEOXYCHOLIC ACID
  • 2-([3α,7α-dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt
  • NSC681055
  • Taurochenodeoxycholic acid sodium salt, 2-([3α,7α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt, 3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt
  • Ethanesulfonic Acid,2-[[(3A,5B,7A-3,7-Dihydroxy-24-OxocholaN-24-Yl]Amino]-, Sodium Salt (1:1
  • Taurochenodeoxycholic Acid-[d9] Sodium Salt
  • Ethanesulfonic acid, 2-[[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)
  • Chenodeoxycholic Acid Impurity
  • Sodium taurochenodeoxycholate-2,2,4,4-d4 >=98 atom % D, >=97% (CP)
  • Taurochenodeoxycholic Acid Sodium SaltQ: What is Taurochenodeoxycholic Acid Sodium Salt Q: What is the CAS Number of Taurochenodeoxycholic Acid Sodium Salt Q: What is the storage condition of Taurochenodeoxycholic Acid Sodium Salt
  • Sodium Taurochenodeoxycholate (STCDC) extrapure, 95%
  • 2H9]-Taurochenodeoxycholic Acid Sodium Salt
  • Sodium 2-((4R)-4-((3R,7R,10S,13R,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonate
  • Urosodeoxycholic Acid Impurity 15
  • 5β-CHOLANIC ACID-3α, 7α-DIOL N-(2-SULPHOETHYL)-AMIDE
  • Taurine goose deoxycholate sodium
  • Taurochenodeoxycholic Acid Sodium Salt in Methanol
  • 2-([3α,7α-Dihydroxy-24-Oxo-5β-Cholan-24-Yl]Amino)Ethanesulfonic Acid
  • 5β-Cholanic Acid-3α-, 7α-Diol N-(2-Sulphoethyl)-Amide Sodium Salt
  • Taurochenodeoxycholic acid sodium, 10 mM in DMSO
  • Aurochenodeoxycholic acid sodiuM salt
  • Taurochenodeoxycholic acid sodium salt 97%
  • D9-Taurochenodeoxycholic Acid Sodium Salt
  • D4-Taurochenodeoxycholic Acid Sodium Salt
  • 6009-98-9
  • C26H44NO6SNa
  • C26H45NNaO6S
  • Anionic
  • BioChemical
  • Detergents
  • 6009-98-9