3,5-Dimethoxybenzonitrile
Uses- Product Name
- 3,5-Dimethoxybenzonitrile
- CAS No.
- 19179-31-8
- Chemical Name
- 3,5-Dimethoxybenzonitrile
- Synonyms
- Benzonitrile, 3,5-dimethoxy-;35.1;TIMTEC-BB SBB008557;3,5-Dimethoxybenzoni;3,5-DIMETHOXYBENZONITRILE;3,5-dimethoxy-benzonitril;1-Cyano-3,5-dimethoxybenzene;3,5-diMethoxybenzene nitrile;3,5-Dimethoxybenzonitrile,97%;3,5-DiMethoxybenzonitrile, 98%+
- CBNumber
- CB1281495
- Molecular Formula
- C9H9NO2
- Formula Weight
- 163.17
- MOL File
- 19179-31-8.mol
3,5-Dimethoxybenzonitrile Property
- Melting point:
- 87-89 °C(lit.)
- Boiling point:
- 290.25°C (rough estimate)
- Density
- 1.2021 (rough estimate)
- refractive index
- 1.5300 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C9H9NO2/c1-11-8-3-7(6-10)4-9(5-8)12-2/h3-5H,1-2H3
- InChIKey
- NVTHWSJNXVDIKR-UHFFFAOYSA-N
- SMILES
- C(#N)C1=CC(OC)=CC(OC)=C1
- CAS DataBase Reference
- 19179-31-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36-36/37
- RIDADR
- 3276
- WGK Germany
- 3
- RTECS
- DI4355800
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29269090
- Toxicity
- mouse,LD50,intraperitoneal,1gm/kg (1000mg/kg),Farmaco, Edizione Scientifica. Vol. 41, Pg. 41, 1986.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D132330
- Product name
- 3,5-Dimethoxybenzonitrile
- Purity
- 99%
- Packaging
- 25g
- Price
- $223
- Updated
- 2023/01/07
- Product number
- D525955
- Product name
- 3,5-Dimethoxybenzonitrile
- Packaging
- 5g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FD31244
- Product name
- 3,5-Dimethoxybenzonitrile
- Packaging
- 10g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- JK335551
- Product name
- 3,5-Dimethoxybenzonitrile
- Purity
- 97%
- Packaging
- 5g
- Price
- $64
- Updated
- 2021/12/16
- Product number
- F452
- Product name
- 3,5-Dimethoxybenzonitrile
- Packaging
- 1g
- Price
- $64
- Updated
- 2021/12/16
3,5-Dimethoxybenzonitrile Chemical Properties,Usage,Production
Uses
3,5-Dimethoxybenzonitrile can be used as a pharmaceutical intermediate and can also participate in various organic synthesis processes.
Chemical Properties
white to beige or grey crystalline powder
Synthesis
705-76-0
19179-31-8
General procedure for the synthesis of 3,5-dimethoxybenzonitrile from 3,5-dimethoxybenzenemethanol: In a 25 mL Schlenk tube equipped with a magnetic stirrer, CuCl (0.05 mmol, 5 mol%), DABCO (0.10 mmol, 10 mol%), and 4-HO-TEMPO (0.05 mmol, 5 mol%) were added in turn . Subsequently, a solution of 3,5-dimethoxybenzyl alcohol (1 mmol) and ammonia (25-28%, 3 mmol, 3.0 equiv) in acetonitrile (2 mL) was added. The reaction mixture was stirred at room temperature for 24 h under argon protection. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was diluted with water and extracted with ethyl acetate. The organic layers were combined and dried with anhydrous magnesium sulfate. Subsequently, the organic layer was concentrated under reduced pressure and the crude product was purified by column chromatography to afford the target product 3,5-dimethoxybenzonitrile.
References
[1] Chinese Chemical Letters, 2018, vol. 29, # 3, p. 464 - 466
[2] Applied Organometallic Chemistry, 2018, vol. 32, # 4,
3,5-Dimethoxybenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
3,5-Dimethoxybenzonitrile Suppliers
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- Slovakia
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View Lastest Price from 3,5-Dimethoxybenzonitrile manufacturers
- Product
- 3,5-Dimethoxybenzonitrile 19179-31-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-09
- Product
- 3,5-Dimethoxybenzonitrile 19179-31-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 3,5-Dimethoxybenzonitrile 19179-31-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-02