2-(4-Chlorophenoxy)-2-methylpropionic acid

Product Name: 2-(4-Chlorophenoxy)-2-methylpropionic acid
CAS No.: 882-09-7
Chemical Name: 2-(4-Chlorophenoxy)-2-methylpropionic acid
Synonyms: PCIB;PCPIB;4-CPIB;Regadrin;Clofibrin;Regulipid;Clofibric;Arteriohom;Prestwick_39;AKOS BB-7852
CBNumber: CB1282957
Molecular Formula: C10H11ClO3
Formula Weight: 214.65
MOL File: 882-09-7.mol

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2-(4-Chlorophenoxy)-2-methylpropionic acid Property

Melting point:: 120-122 °C(lit.)
Boiling point:: 308.11°C (rough estimate)
Density: 1.2413 (rough estimate)
refractive index: 1.5220 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform, Methanol
form: Crystals or Crystalline Powder
pka: 3.18±0.10(Predicted)
color: Pale yellow to brownish
Merck: 14,2378
BRN: 1874067
CAS DataBase Reference: 882-09-7(CAS DataBase Reference)
NIST Chemistry Reference: Clofibric acid(882-09-7)
EPA Substance Registry System: Propanoic acid, 2-(4-chlorophenoxy)-2-methyl- (882-09-7)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-20/21/22
Safety Statements: 36-24/25
WGK Germany: 3
RTECS: UE9455000
HazardClass: IRRITANT
HS Code: 29189900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 90323
Product name: Clofibric acid
Purity: analytical standard
Packaging: 100mg
Price: $85.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: 197777
Product name: 2-(p-Chlorophenoxy)-2-methylpropionic acid
Purity: 97%
Packaging: 50g
Price: $109
Updated: 2024/03/01

TCI Chemical

Product number: C0940
Product name: 2-(4-Chlorophenoxy)isobutyric Acid
Purity: >97.0%(T)
Packaging: 25g
Price: $42
Updated: 2024/03/01

TCI Chemical

Product number: C0940
Product name: 2-(4-Chlorophenoxy)isobutyric Acid
Purity: >97.0%(T)
Packaging: 500g
Price: $501
Updated: 2023/06/20

Cayman Chemical

Product number: 21608
Product name: Clofibric Acid
Purity: ≥98%
Packaging: 10g
Price: $31
Updated: 2024/03/01

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2-(4-Chlorophenoxy)-2-methylpropionic acid Chemical Properties,Usage,Production

Description

Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC₅₀ = 50 μM in a transactivation assay) and the active metabolite of clofibrate . It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxaloacetate transaminase (GOT) levels and increases glutamate pyruvate transaminase (GPT) and lactate dehydrogenase (LDH) levels, markers of xenobiotic stress, in the plasma of carp (C. carpio) when administered in tank water at a concentration of 10 μg/L. Clofibric acid has been found in wastewater effluent.

Chemical Properties

Pale Yellow Solid

Uses

Antilipemic.

Uses

herbicide, antihyperlipoproteinemic, antineoplastic

Uses

A hypolipidemic compound

Definition

ChEBI: A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.

Biological Activity

PPAR agonist. Antihyperlipoproteinemic.

2-(4-Chlorophenoxy)-2-methylpropionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Clofibrate

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2-(4-Chlorophenoxy)-2-methylpropionic acid Suppliers

Americas 1 Belgium 2 Canada 3 China 221 Europe 3 France 1 Germany 8 India 11 Japan 5 Switzerland 3 Ukraine 2 United Kingdom 14 United States 56 Global 330

J & K SCIENTIFIC LTD.

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View Lastest Price from 2-(4-Chlorophenoxy)-2-methylpropionic acid manufacturers

Hebei Duling International Trade Co. LTD

Product: 2-(4-Chlorophenoxy)-2-methylpropionic acid 882-09-7
Price: US $35.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 tons
Release date: 2023-01-30

Henan Fengda Chemical Co., Ltd

Product: Clofibric acid 882-09-7
Price: US $50.00-1.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: g-kg-tons,free sample is available
Release date: 2024-01-03

Hebei Yanxi Chemical Co., Ltd.

Product: 2-(4-Chlorophenoxy)-2-methylpropionic acid 882-09-7
Price: US $30.00-10.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-11-20

882-09-7, 2-(4-Chlorophenoxy)-2-methylpropionic acidRelated Search:

Methyltrimethoxysilane Sucrose acetate isobutyrate 2,2-Bis(hydroxymethyl)propionic acid Methyltriethoxysilane Dimethyldimethoxysilane Ethyl 2-(Chlorosulfonyl)acetate Folic acid Glycine 4-Chlorophenoxyacetic acid Isobutyric acid 3-(4-Methoxyphenyl)propionic acid OCTYL ISOBUTYRATE Citric acid Methyl 2-bromo-2-methylpropionate Diethoxydimethylsilane 4-Hydrazinobenzene-1-sulfonamide hydrochloride 4-Chlorophenylacetic acid Ascoric Acid

CLOFIBRIC ACID

4-Chorophenoxy-d-methylpropionicacid

4-CPIB

Chlorobenzene oxygenisobutyrate

Acetic acid, (p-chlorop

Prestwick_39

2-(4-Chlorophe

Acetic acid, (p-chlorophenoxy)dimethyl-

Acide (p-chlorophenoxy)-2 methyl-2 propionique

acide(p-chlorophenoxy)-2methyl-2propionique

alpha-(4-Chlorophenoxy)-alpha-methylpropionic acid

alpha-(4-Chlorophenoxy)isobutyric acid

Chlorfibrinic acid

Chlorofibrinic acid

Chlorophibrinic acid

chlorophibrinicacid

Clofibrate free acid

Clofibrin

Clofibrinsaeure

p-(2,4-Chlorophenoxy)isobutyric acid

p-Chlorophenoxyisobutyricacid

PCIB

Clofibric aCld

2-(4-Chlorophenoxy)-2-methylpropionic acid≥ 99% (HPLC)

2-(4-Chlorophenoxy)-2-methylpropionic acid (Clofibric acid) 10 μg/mL in Acetonitrile

2-(4-Chlorophenoxy)-2-methylpropanoic acid 97+%

CLOFIBRINIC ACID

ASISCHEM A27485

2-(P-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID

2-(4-CHLOROPHENOXY)ISOBUTYRIC ACID

2-(4-CHLOROPHENOXY)-2-METHYLPROPANOIC ACID

2-(4-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID

4-CHLOROPHENOXY-ISO-BUTYRIC ACID

RARECHEM AL BO 0794

TIMTEC-BB SBB008306

AKOS BB-7852

AKOS B013926

ALPHA-(P-CHLOROPHENOXY)ISOBUTYRIC ACID

(Chlorophenoxy)isobutyric acid

(p-chlorophenoxy)dimethyl-aceticaci

(p-Chlorophenoxy)isobutyric acid

2-(p-chlorophenoxy)-2-methyl-propionicaci

2-(p-Chlorophenoxy)isobutyric acid

PCPIB

Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-

Propanoic acid, 2-methyl, 2-(4-chlorophenyloxy)

Propionic acid, 2-(p-chlorophenoxy)-2-methyl-

Regadrin

Regulipid

2-(4-Chlorophenoxy)-2-methylpropionic acid~Clofibric acid

4-CHLOROPHENOXY-ISO-BUTYRCC ACID

p-chlorophenoxyisobutyrate

ClofibricAcid98%

[p-Chlorophenoxy]-2-methylpropionic acid

a-(p-Chlorophenoxy)isobutyric Acid

Arteriohom

4-Chlorophenoxy

Clofibric