ChemicalBook > CAS DataBase List > AC-DEVD-AMC
AC-DEVD-AMC
- Product Name
- AC-DEVD-AMC
- CAS No.
- 169332-61-0
- Chemical Name
- AC-DEVD-AMC
- Synonyms
- Ac-Devd;AC-DEVD-AMC;AC-DMQD-AMC;AC-DEVD-MCA;ACETYL-DEVD-AMC;AC-DEVD-AMC USP/EP/BP;AC-ASP-MET-GLN-ASP-AMC;AC-ASP-GLU-VAL-ASP-MCA;AC-ASP-GLU-VAL-ASP-AMC;AC-DEVD-AMC AMMONIUM SALT
- CBNumber
- CB1285721
- Molecular Formula
- C30H37N5O13
- Formula Weight
- 675.64
- MOL File
- 169332-61-0.mol
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AC-DEVD-AMC Property
- Boiling point:
- 1200.1±65.0 °C(Predicted)
- Density
- 1.423±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: 10 mM
- form
- powder
- pka
- 4.09±0.10(Predicted)
- color
- white
- Sequence
- N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Methylcoumarin
- InChIKey
- ALZSTTDFHZHSCA-RNVDEAKXSA-N
- SMILES
- C12C(C)=CC(=O)OC1=CC(NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)C)CC(=O)O)=CC=2 |&1:13,21,28,37,r|
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 235425
- Product name
- Caspase-3 Substrate II, Fluorogenic
- Purity
- Fluorogenic caspase-3 substrate.
- Packaging
- 1mg
- Price
- $114
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 235425
- Product name
- Caspase-3 Substrate II, Fluorogenic
- Purity
- Fluorogenic caspase-3 substrate.
- Packaging
- 5mg
- Price
- $461
- Updated
- 2025/07/31
Cayman Chemical
- Product number
- 14986
- Product name
- Ac-DEVD-AMC
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $61
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 14986
- Product name
- Ac-DEVD-AMC
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $162
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- A1086
- Product name
- N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin
- Purity
- ≥97% (HPLC), powder
- Packaging
- 5mg
- Price
- $489
- Updated
- 2025/07/31
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AC-DEVD-AMC Chemical Properties,Usage,Production
Description
Ac-DEVD-AMC is a fluorogenic substrate for caspase-3. Caspase activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.
Uses
N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin has been used as a substrate for caspase-3 assay in human colon cancer cell line and in bone marrow mesenchymal stem cells.
Biochem/physiol Actions
Fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
Excitation / Emission Maximum
340-360 nm/440-460 nm
Sequene
Ac-Asp-Glu-Val-Asp-AMC
AC-DEVD-AMC Preparation Products And Raw materials
Raw materials
Preparation Products
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169332-61-0, AC-DEVD-AMCRelated Search:
4-Methylcumarin
N-acetyl aspartyl-glutaMic acid
AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN
AC-DEVD-AFC
AC-DEVD-CHO
AC-DEVD-AMC
4-(3-METHOXY-PHENYLAMINO)-BUTAN-1-OL
4-(3-METHOXYANILINO)-4-OXOBUTANOIC ACID
CHEMBRDG-BB 5539774
CASPASE-3 SUBSTRATE AC-DEVD-AMC TFA
SUC-ALA-ALA-ALA-AMC