ChemicalBook > CAS DataBase List > P-Toluenesulfonic anhydride

P-Toluenesulfonic anhydride

Product Name
P-Toluenesulfonic anhydride
CAS No.
4124-41-8
Chemical Name
P-Toluenesulfonic anhydride
Synonyms
4-Methylbenzenesulfonic anhydride;p-Tolylsulfonyl 4-methylbenzenesulfonate;Tosic anhydride;Toluene-p-anhydride;3-Toluenesulfonicanhydride;P-TOLUENESULFONIC ANHYDRIDE;4-TOLUENESULFONIC ANHYDRIDE;p-Toluenesulfonyl anhydride;TOLUENE-4-SULFONIC ANHYDRIDE;P-TOLUENESULPHONIC ANHYDRIDE
CBNumber
CB1292293
Molecular Formula
C14H14O5S2
Formula Weight
326.38
MOL File
4124-41-8.mol
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P-Toluenesulfonic anhydride Property

Melting point:
121-127 °C(lit.)
Boiling point:
478.0±48.0 °C(Predicted)
Density 
1.361±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
form 
Powder, Crystals and/or Chunks
color 
Off-white to gray
Sensitive 
Moisture Sensitive
BRN 
2223702
InChIKey
PDVFSPNIEOYOQL-UHFFFAOYSA-N
CAS DataBase Reference
4124-41-8(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2585 8/PG 3
WGK Germany 
3
F 
10-21
Hazard Note 
Irritant
HazardClass 
8
PackingGroup 
II
HS Code 
29041000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
259764
Product name
p-Toluenesulfonic anhydride
Purity
97%
Packaging
5g
Price
$54.8
Updated
2024/03/01
Sigma-Aldrich
Product number
259764
Product name
p-Toluenesulfonic anhydride
Purity
97%
Packaging
25g
Price
$142
Updated
2024/03/01
TCI Chemical
Product number
T1485
Product name
p-Toluenesulfonic Anhydride
Purity
>95.0%(T)
Packaging
5g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
T1485
Product name
p-Toluenesulfonic Anhydride
Purity
>95.0%(T)
Packaging
25g
Price
$134
Updated
2024/03/01
Alfa Aesar
Product number
L00160
Product name
p-Toluenesulfonic anhydride, 97%
Packaging
5g
Price
$41.65
Updated
2024/03/01
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P-Toluenesulfonic anhydride Chemical Properties,Usage,Production

Chemical Properties

Off-white to cream powder

Uses

p-Toluenesulfonic anhydride has been employed as reagent in palladium-catalyzed allylic alkenylation of allylic alcohols with n-butyl acrylate.

General Description

p-Toluenesulfonic anhydride acts as electrophilic species and activates 2-deoxy-sugar hemiacetals in situ, which reacts stereoselectively with nucleophilic acceptors to afford β-anomers.

Synthesis

Add p-toluenesulfonic acid and an m-phosphorous compound used as raw materials into a reaction kettle, dropwise adding thionyl chloride while stirring. Controlling the temperature in the reaction kettle at 68-76 ℃ and heating to perform condensation after dropwise addition; inputting water and hydrochloric acid into the reaction kettle, cooling to 0 ℃. The reaction solution generated in the previous step was drawn into the water, vacuum filtration was performed, and centrifuging was used to obtain a crude product, p-toluenesulfonic anhydride. Furthermore, it was inputting ethyl acetate, performing heating reflux, and freezing to perform crystallization, thus obtaining the qualified finished product.

P-Toluenesulfonic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

2-Aminoquinoline
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P-Toluenesulfonic anhydride Suppliers

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View Lastest Price from P-Toluenesulfonic anhydride manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
P-Toluenesulfonic anhydride 4124-41-8
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-20
Shaanxi Dideu Medichem Co. Ltd
Product
P-Toluenesulfonic anhydride 4124-41-8
Price
US $1.00-50.00/KG
Min. Order
1KG
Purity
99%+
Supply Ability
500KG
Release date
2024-05-17
Henan Fengda Chemical Co., Ltd
Product
4-Methylbenzenesulfonic Anhydride 4124-41-8
Price
US $6.00-0.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-18

4124-41-8, P-Toluenesulfonic anhydrideRelated Search:

CIS-BUTENEDIOIC ANHYDRIDE Glutaric anhydride Tosyl cyanide Trifluoromethanesulfonic anhydride TOLBUTAMIDE Succinic anhydride Isatoic Anhydride p-Toluenesulfonic acid Iron(III) p-toluenesulfonate p-Toluenesulfonamide Phthalic anhydride Sodium p-toluenesulfonate Tosyl chloride p-Toluenesulfonyl Isocyanate Ethyl p-toluenesulfonate p-Toluenesulfonic acid monohydrate Methyl p-toluenesulfonate P-TOLUENESULFONIC ACID N-BUTYL ESTER

  • P-TOLUENESULFONIC ANHYDRIDE
  • P-TOLUENESULPHONIC ANHYDRIDE
  • TOLUENE-4-SULFONIC ANHYDRIDE
  • 1,3-BIS(4-METHYLPHENYL)-1,1,3,3-TETRAOXO-1LAMBDA6,3LAMBDA6-DITHIOXANE
  • 4-TOLUENESULPHONIC ANHYDRIDE
  • 4-Methylbenzenesulfonic anhydride
  • Tosic anhydride
  • toluene-p-sulphonic anhydride
  • 4-Toluenesulphonic acid anhydride
  • 4-TOLUENESULFONIC ANHYDRIDE
  • 3-Toluenesulfonicanhydride
  • Toluene-4-sulphonic anhydride 95%
  • p-Toluenesulfonic anhydride 5GR
  • (4-Methylphenyl)sulfonyl 4-methylbenzenesulfonate
  • Toluene-4-sulfonic acid anhydride
  • Toluene-p-anhydride
  • Bis(4-methylbenzenesulfonic)anhydride
  • Bis(p-toluenesulfonic)anhydride
  • Di-p-toluenesulfonic anhydride
  • <i>p</i>-Toluenesulfonic Anhydride
  • p-Toluenesulfonyl anhydride
  • (4-Methylbenzene)sulfonyl 4-Methylbenzene-1-sulfonate
  • 4-Methylbenzenesulphonic anhydride, Tosic anhydride
  • Toluene-4-sulphonic anhydride
  • p-Toluenesulfonic anhydride 97%
  • p-Methylbenzenesulfonic anhydride
  • p-Toluenesulfonic anhydride, 98%+
  • p-Toluenesulfonic anhydride, 95%, for synthesis
  • Benzenesulfonic acid, 4-methyl-, 1,1'-anhydride
  • p-Tolylsulfonyl 4-methylbenzenesulfonate
  • High Quality Pharmaceutical Intermediates P-Toluenesulfonic Anhydride
  • 7-butoxybenzene-sulfonylchloride
  • p-Toluenesulfonic anhydride (6CI, 7CI, 8CI)
  • Toluenesulfonic anhydride (stored in the freezer, easy to decompose at high temperatures)
  • 4124-41-8
  • CH3C6H4SO22O
  • C14H14O5S2
  • Protection & Derivatization Reagents (for Synthesis)
  • Building Blocks
  • Organic Building Blocks
  • Sulfur Compounds
  • Sulfonic/Sulfinic Acid Anhydrides
  • Pyridines
  • Sulfonic/Sulfinic Acid Anhydrides
  • Building Blocks
  • Chemical Synthesis
  • Organic Building Blocks
  • Sulfur Compounds
  • Protection & Derivatization Reagents (for Synthesis)
  • Synthetic Organic Chemistry
  • Organic Building Blocks
  • Sulfonic/Sulfinic Acid Anhydrides
  • Sulfur Compounds
  • bc0001