2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE
- Product Name
- 2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE
- CAS No.
- 14080-51-4
- Chemical Name
- 2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE
- Synonyms
- AKOS 93830;AKOS B014696;CHEMBRDG-BB 3014696;ART-CHEM-BB B014696;TIMTEC-BB SBB007065;2-AMino-3-carbaMoylthiophene;2-AMINOTHIOPHENE-3-CARBOXAMIDE;2-AMINO-3-THIOPHENECARBOXAMIDE;3-Thiophenecarboxamide, 2-amino-;2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE
- CBNumber
- CB1293472
- Molecular Formula
- C5H6N2OS
- Formula Weight
- 142.18
- MOL File
- 14080-51-4.mol
2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE Property
- Melting point:
- 153-155°C
- Boiling point:
- 321.8±22.0 °C(Predicted)
- Density
- 1.423±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- powder to crystal
- pka
- 15.58±0.50(Predicted)
- color
- White to Orange to Green
- InChI
- InChI=1S/C5H6N2OS/c6-4(8)3-1-2-9-5(3)7/h1-2H,7H2,(H2,6,8)
- InChIKey
- WHZIZZOTISTHCT-UHFFFAOYSA-N
- SMILES
- C1(N)SC=CC=1C(N)=O
- CAS DataBase Reference
- 14080-51-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS007582
- Product name
- 2-amino-thiophene-3-carboxylic acid amide
- Purity
- AldrichCPR
- Packaging
- 500MG
- Price
- $107
- Updated
- 2025/07/31
- Product number
- A3165
- Product name
- 2-Aminothiophene-3-carboxamide
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $29
- Updated
- 2025/07/31
- Product number
- A3165
- Product name
- 2-Aminothiophene-3-carboxamide
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $138
- Updated
- 2025/07/31
- Product number
- A615605
- Product name
- 2-Aminothiophene-3-carboxamide
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A615605
- Product name
- 2-Aminothiophene-3-carboxamide
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE Chemical Properties,Usage,Production
Synthesis
40018-26-6
107-91-5
14080-51-4
General procedure for the synthesis of 2-aminothiophene-3-amides from 1,4-dithio-2,5-diol and cyanoacetamide: Triethylamine (36 mL, 256 mmol) was added to a solution of ethanol (400 mL) containing 2-cyanoacetamide (10.8 g, 128 mmol) and 1,4-dithiazan-2,5-diol (19.5 g, 128 mmol). The reaction mixture was stirred at room temperature for 5 minutes and then heated to reflux for 2 hours. After completion of the reaction, the mixture was cooled to room temperature, filtered and concentrated in vacuum. The residue was dissolved in ethyl acetate (400 mL) and washed sequentially with 1 M aqueous sodium hydroxide (200 mL), water (2 x 200 mL) and brine (200 mL). The organic layer was dried over anhydrous sodium sulfate and concentrated in vacuo to give 2-aminothiophene-3-amide (16 g, 113 mmol, 88% yield) as a light yellow solid.LC-MS [M+H]+ m/z 143.
References
[1] Patent: WO2003/104218, 2003, A1. Location in patent: Page 13
[2] Synthesis (Germany), 2013, vol. 45, # 1, p. 45 - 52
[3] Patent: WO2012/30894, 2012, A1. Location in patent: Page/Page column 87
[4] Tetrahedron Letters, 2007, vol. 48, # 30, p. 5261 - 5264
[5] Journal of Medicinal Chemistry, 2011, vol. 54, # 19, p. 6734 - 6750
2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE Suppliers
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
- Tel
- --
- Fax
- --
- contact@chemcollect.de
- Country
- Germany
- ProdList
- 6214
- Advantage
- 54
- Tel
- --
- Fax
- --
- akos@akosgmbh.de
- Country
- Germany
- ProdList
- 6717
- Advantage
- 72
View Lastest Price from 2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE manufacturers
- Product
- 2-Amino-3-thiophenecarboxamide 14080-51-4
- Price
- US $1.60-6.60/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19
- Product
- 2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE 14080-51-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 2-AMINO-THIOPHENE-3-CARBOXYLIC ACID AMIDE 14080-51-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-14