ChemicalBook > CAS DataBase List > Hydroxypioglitazone
Hydroxypioglitazone
- Product Name
- Hydroxypioglitazone
- CAS No.
- 146062-44-4
- Chemical Name
- Hydroxypioglitazone
- Synonyms
- Leriglitazone;HYDROXYPIOGLITAZONE;Hydroxypioglitazone M4;Pioglitazone Impurity 4;Pioglitazone Impurity 18;Pioglitazone M4 Metabolite;Pioglitazone, hydroxy M-IV;Hydroxy Pioglitazone (M-IV) ;Hydroxy Pioglitazone Solution, 100ppm;5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE
- CBNumber
- CB1299313
- Molecular Formula
- C19H20N2O4S
- Formula Weight
- 372.44
- MOL File
- 146062-44-4.mol
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Hydroxypioglitazone Property
- Melting point:
- 157-1580C
- Boiling point:
- 627.6±55.0 °C(Predicted)
- Density
- 1.325±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated)
- pka
- 6.35±0.50(Predicted)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 146062-44-4
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 28043
- Product name
- Hydroxy Pioglitazone
- Packaging
- 1mg
- Price
- $275
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28043
- Product name
- Hydroxy Pioglitazone
- Packaging
- 5mg
- Price
- $820
- Updated
- 2024/03/01
Usbiological
- Product number
- H9111-17
- Product name
- Hydroxy Pioglitazone
- Packaging
- 500ug
- Price
- $496
- Updated
- 2021/12/16
Usbiological
- Product number
- 014338
- Product name
- Hydroxy Pioglitazone
- Packaging
- 1mg
- Price
- $566
- Updated
- 2021/12/16
Usbiological
- Product number
- 014337
- Product name
- Hydroxy Pioglitazone
- Packaging
- 1mg
- Price
- $602
- Updated
- 2021/12/16
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Hydroxypioglitazone Chemical Properties,Usage,Production
Description
Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone (Item Nos. 71745 | 22263 | 10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to PPARγ (Ki = 1.2 μM) and activates PPARγ in a time-resolved FRET (TR-FRET) assay (EC50 = 2.1 μM).
Chemical Properties
Off-White Solid
Uses
A metabolite of Pioglitazone (P471000).
Definition
ChEBI: Hydroxypioglitazone is a member of the class of thiazolidenediones that is the hydroxy derivative of pioglitazone. It has a role as a human xenobiotic metabolite. It is a member of thiazolidinediones, a member of pyridines and an aromatic ether. It is functionally related to a pioglitazone.
Hydroxypioglitazone Preparation Products And Raw materials
Raw materials
Preparation Products
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Hydroxypioglitazone Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
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View Lastest Price from Hydroxypioglitazone manufacturers
Career Henan Chemical Co
- Product
- Hydroxypioglitazone 146062-44-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24
146062-44-4, HydroxypioglitazoneRelated Search:
Pioglitazone
4'-Hydroxyacetophenone
Pioglitazone
Troglitazone
Gliquidone
Pioglitazone hydrochloride
a-[(Aminocarbonyl)thio]-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzenepropanoic Acid Ethyl Ester
Pioglitazone Aldehyde Impurity
5-(4-Fluorobenzyl)-2,4-thiazolidinedione
4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyaldehyde
Hydroxy Pioglitazone (M-II) (Mixture of Diastereomers)
Pioglitazone Sulfonic Acid IMpurity
2-[2-(4-BroMophenoxy)ethyl]-5-ethylpyridine
Pioglitazone Impurity
5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone
Pioglitazone N-Oxide
5-(4-Hydroxybenzyl)-2,4-thiazolidinedione
5-[[4-[2-(5-ACETYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL]-2,4THIAZOLIDINEDIONE