Hydroxypioglitazone

Product Name: Hydroxypioglitazone
CAS No.: 146062-44-4
Chemical Name: Hydroxypioglitazone
Synonyms: Leriglitazone;HYDROXYPIOGLITAZONE;Hydroxypioglitazone M4;Pioglitazone Impurity 4;Pioglitazone Impurity 18;Pioglitazone M4 Metabolite;Pioglitazone, hydroxy M-IV;Hydroxy Pioglitazone (M-IV);Hydroxy Pioglitazone Solution, 100ppm;5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE
CBNumber: CB1299313
Molecular Formula: C19H20N2O4S
Formula Weight: 372.44
MOL File: 146062-44-4.mol

More

Less

Hydroxypioglitazone Property

Melting point:: 157-1580C
Boiling point:: 627.6±55.0 °C(Predicted)
Density: 1.325±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under Inert Atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
pka: 6.35±0.50(Predicted)
form: Solid
color: White to Off-White
Stability:: Hygroscopic
CAS DataBase Reference: 146062-44-4

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 28043
Product name: Hydroxy Pioglitazone
Packaging: 1mg
Price: $275
Updated: 2024/03/01

Cayman Chemical

Product number: 28043
Product name: Hydroxy Pioglitazone
Packaging: 5mg
Price: $820
Updated: 2024/03/01

Usbiological

Product number: 293691
Product name: Hydroxy pioglitazone
Packaging: 1mg
Price: $827
Updated: 2021/12/16

Usbiological

Product number: 293692
Product name: Hydroxy pioglitazone
Packaging: 1mg
Price: $891
Updated: 2021/12/16

TRC

Product number: H952075
Product name: HydroxyPioglitazone(M-IV)
Packaging: 10mg
Price: $1450
Updated: 2021/12/16

More

Less

Hydroxypioglitazone Chemical Properties,Usage,Production

Description

Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone (Item Nos. 71745 | 22263 | 10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to PPARγ (K_i = 1.2 μM) and activates PPARγ in a time-resolved FRET (TR-FRET) assay (EC₅₀ = 2.1 μM).

Chemical Properties

Off-White Solid

Uses

A metabolite of Pioglitazone (P471000).

Definition

ChEBI: Hydroxypioglitazone is a member of the class of thiazolidenediones that is the hydroxy derivative of pioglitazone. It has a role as a human xenobiotic metabolite. It is a member of thiazolidinediones, a member of pyridines and an aromatic ether. It is functionally related to a pioglitazone.

Hydroxypioglitazone Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Hydroxypioglitazone Suppliers

Canada 4 China 48 France 1 Germany 1 India 5 United Kingdom 1 United States 16 Global 76

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

Clearsynth Labs Limited

Tel: +91-22-26355700
Fax: +91-22-26355701
Email: info@clearsynth.com
Country: India
ProdList: 9679
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1955
Advantage: 55

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9648
Advantage: 58

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4511
Advantage: 55

More

Less

View Lastest Price from Hydroxypioglitazone manufacturers

Career Henan Chemical Co

Product: Hydroxypioglitazone 146062-44-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 100kg
Release date: 2018-12-24

146062-44-4, HydroxypioglitazoneRelated Search:

Pioglitazone 4'-Hydroxyacetophenone Pioglitazone Troglitazone Gliquidone Pioglitazone hydrochloride a-[(Aminocarbonyl)thio]-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzenepropanoic Acid Ethyl Ester Pioglitazone Aldehyde Impurity 5-(4-Fluorobenzyl)-2,4-thiazolidinedione 4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyaldehyde Hydroxy Pioglitazone (M-II) (Mixture of Diastereomers) Pioglitazone Sulfonic Acid IMpurity 2-[2-(4-BroMophenoxy)ethyl]-5-ethylpyridine Pioglitazone Impurity 5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone Pioglitazone N-Oxide 5-(4-Hydroxybenzyl)-2,4-thiazolidinedione 5-[[4-[2-(5-ACETYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL]-2,4THIAZOLIDINEDIONE

HYDROXYPIOGLITAZONE

Hydroxy Pioglitazone (M-IV)

5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE

Pioglitazone, hydroxy M-IV

Pioglitazone Impurity 18

Hydroxy Pioglitazone Solution, 100ppm

Pioglitazone M4 Metabolite

Leriglitazone

Pioglitazone Impurity 4

2,4-Thiazolidinedione, 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-

Hydroxypioglitazone M4

146062-44-4

Sulfur & Selenium Compounds

Various Metabolites and Impurities

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals