methyl 3-bromo-5-fluoro-2-methylbenzoate
- Product Name
- methyl 3-bromo-5-fluoro-2-methylbenzoate
- CAS No.
- 1187318-53-1
- Chemical Name
- methyl 3-bromo-5-fluoro-2-methylbenzoate
- Synonyms
- methyl 3-bromo-5-fluoro-2-methylbenzoate;3-BROMO-5-FLUORO-2-METHYL-BENZOIC ACID METHYL ESTER;Benzoic acid, 3-bromo-5-fluoro-2-methyl-, methyl ester
- CBNumber
- CB13033143
- Molecular Formula
- C9H8BrFO2
- Formula Weight
- 247.06
- MOL File
- 1187318-53-1.mol
methyl 3-bromo-5-fluoro-2-methylbenzoate Property
- Boiling point:
- 262.9±40.0 °C(Predicted)
- Density
- 1.506±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Appearance
- Colorless to light yellow Solid-Liquid Mixture
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B679560
- Product name
- 3-Bromo-5-fluoro-2-methyl-benzoicAcidMethylEster
- Packaging
- 500mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- PC510281
- Product name
- Methyl 3-Bromo-5-fluoro-2-methylbenzoate
- Packaging
- 5g
- Price
- $1122
- Updated
- 2021/12/16
- Product number
- CS-0061182
- Product name
- Methyl3-bromo-5-fluoro-2-methylbenzoate
- Packaging
- 5g
- Price
- $597
- Updated
- 2021/12/16
- Product number
- CS-0061182
- Product name
- Methyl3-bromo-5-fluoro-2-methylbenzoate
- Packaging
- 100mg
- Price
- $54
- Updated
- 2021/12/16
- Product number
- CS-0061182
- Product name
- Methyl3-bromo-5-fluoro-2-methylbenzoate
- Packaging
- 250mg
- Price
- $94
- Updated
- 2021/12/16
methyl 3-bromo-5-fluoro-2-methylbenzoate Chemical Properties,Usage,Production
Synthesis
67-56-1
1187318-52-0
1187318-53-1
At room temperature, 2-methyl-3-bromo-5-fluorobenzoic acid (4.2 g, crude) was dissolved in methanol (16 mL) and thionyl chloride (2.5 mL) was added slowly. The reaction mixture was heated to 70 °C with continuous stirring for 3 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was removed under reduced pressure by rotary evaporator to give the crude product. The crude product was purified by silica gel column chromatography with the eluent of petroleum ether/ethyl acetate (50:1, v/v) to afford methyl 3-bromo-5-fluoro-2-methylbenzoate (2.3 g, 51% yield) as a yellow oil.
References
[1] Patent: WO2017/201069, 2017, A1. Location in patent: Paragraph 0516
methyl 3-bromo-5-fluoro-2-methylbenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
methyl 3-bromo-5-fluoro-2-methylbenzoate Suppliers
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