SPDP-PEG6-NHS ester

Product Name: SPDP-PEG6-NHS ester
CAS No.: 1818294-32-4
Chemical Name: SPDP-PEG6-NHS ester
Synonyms: SPDP-PEG6-NHS ester;PDP-NH-PEG6-CH2CH2COONHS;Propanoic acid, 3-[[19-oxo-21-(2-pyridinyldithio)-3,6,9,12,15-pentaoxa-18-azaheneicos-1-yl]oxy]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB13062655
Molecular Formula: C27H41N3O11S2
Formula Weight: 647.76
MOL File: 1818294-32-4.mol

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SPDP-PEG6-NHS ester Property

Density: 1.31±0.1 g/cm3(Predicted)
solubility: Soluble in DCM
pka: 15.01±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-21673
Product name: SPDP-PEG6-NHSester
Purity: 95%
Packaging: 100mg
Price: $380
Updated: 2021/12/16

BroadPharm

Product number: BP-21673
Product name: SPDP-PEG6-NHSester
Purity: 95%
Packaging: 250mg
Price: $720
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1788
Product name: SPDP-PEG6-NHS ester
Packaging: 100mg
Price: $740
Updated: 2021/12/16

BroadPharm

Product number: BP-21673
Product name: SPDP-PEG6-NHSester
Purity: 95%
Packaging: 500mg
Price: $1080
Updated: 2021/12/16

Activate Scientific

Product number: AS107959
Product name: SPDP-PEG6-NHSESTER
Purity: 94%
Packaging: 1g
Price: $1530
Updated: 2021/12/16

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SPDP-PEG6-NHS ester Chemical Properties,Usage,Production

Description

SPDP-PEG6-NHS ester is a PEG linker with SPDP and NHS ester moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The NHS ester is amine reactive and forms stable amide bonds. The hydrophilic PEG linker increases the solubility of the compound in aqueous media.

Uses

SPDP-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

SPDP-PEG6-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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SPDP-PEG6-NHS ester Suppliers

China 21 United Kingdom 1 United States 2 Global 24

Jinan elephant international trading co., LTD

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Xi'an Confluore Biological Technology Co., Ltd.

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TargetMol Chemicals Inc.

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Beijing Jin Ming Biotechnology Co., Ltd.

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Affinity（Wuhan）Ltd.

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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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View Lastest Price from SPDP-PEG6-NHS ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: SPDP-PEG6-NHS ester 1818294-32-4
Price: US $0.00/mg
Min. Order: 500mg
Purity: >98.00%
Supply Ability: 500mg
Release date: 2024-03-27

1818294-32-4, SPDP-PEG6-NHS esterRelated Search:

SPDP-PEG9-NHS ester SPDP-PEG10-COOH SPDP-PEG7-NHS ester SPDP-PEG12-NHS ester SPDP-PEG7-COOH SPDP-PEG12-COOH SPDP-PEG3-NHS ester SPDP-PEG4-NHS ester SPDP-PEG6-acid SPDP-PEG2-NHS ester SPDP-PEG3-COOH SPDP-PEG1-NHS ester SPDP SPDP-PEG4-acid SPDP-PEG6-t-butyl ester

SPDP-PEG6-NHS ester

Propanoic acid, 3-[[19-oxo-21-(2-pyridinyldithio)-3,6,9,12,15-pentaoxa-18-azaheneicos-1-yl]oxy]-, 2,5-dioxo-1-pyrrolidinyl ester

PDP-NH-PEG6-CH2CH2COONHS

1818294-32-4

C27H41N3O11S2