ChemicalBook > CAS DataBase List > SPDP
SPDP
- Product Name
- SPDP
- CAS No.
- 68181-17-9
- Chemical Name
- SPDP
- Synonyms
- SPDP;SPDP NHS ester;SPDP Crosslinker;3-(2-PYRIDYLDITHIO)-PROPIONIC ACID-OSU;SUCCINIMIDYL 3-(2-PYRIDYLDITHIO)PROPIONATE;N-SUCCINIMIDYL 3-[2-PYRIDYLDITHIO]PROPIONATE;3-(Pyridin-2-yldisulfanyl)-propionic acid-OS;3-(PYRIDIN-2-YLDISULFANYL)-PROPIONIC ACID-OSU;N-succinimidyl-3-(2-pyridyldithiol)propionate;N-SUCCINIMIDYL-3-(2-PYRIDYLDITHIO)PROPIONANATE
- CBNumber
- CB2446059
- Molecular Formula
- C12H12N2O4S2
- Formula Weight
- 312.36
- MOL File
- 68181-17-9.mol
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SPDP Property
- Melting point:
- 84-86 °C(lit.)
- Boiling point:
- 465.9±55.0 °C(Predicted)
- Density
- 1.48±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- acetone: 50 mg/mL
- form
- powder
- pka
- 1.76±0.19(Predicted)
- color
- White to Light Yellow
- BRN
- 1548137
- Stability:
- Hygroscopic, Moisture Sensitive
- InChIKey
- JWDFQMWEFLOOED-UHFFFAOYSA-N
- CAS DataBase Reference
- 68181-17-9(CAS DataBase Reference)
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- P3415
- Product name
- 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester
- Purity
- ≥95%, powder
- Packaging
- 5mg
- Price
- $67.1
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P3415
- Product name
- 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester
- Purity
- ≥95%, powder
- Packaging
- 25mg
- Price
- $205
- Updated
- 2024/03/01
TCI Chemical
- Product number
- S0819
- Product name
- N-Succinimidyl 3-(2-Pyridyldithio)propionate
- Packaging
- 250MG
- Price
- $174
- Updated
- 2024/03/01
TCI Chemical
- Product number
- S0819
- Product name
- N-Succinimidyl 3-(2-Pyridyldithio)propionate
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $390
- Updated
- 2024/03/01
TCI Chemical
- Product number
- S0819
- Product name
- N-Succinimidyl 3-(2-Pyridyldithio)propionate
- Purity
- >98.0%(HPLC)
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
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SPDP Chemical Properties,Usage,Production
Description
SPDP NHS ester is a heterobiofunctional crosslinker which can react with amine and sulfhydryl groups. SPDP NHS esters are membrane permeable therefore allowing them to funtion inside of cells.
Chemical Properties
White Solid
Uses
Important crosslinking reagent for the preparation of protein-protein and peptide-protein conjugates linked by disulfide bonds.
Uses
3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is useful for the preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
It has been used for antibody conjugation and as a protein cross-linker.
Uses
A heterobifunctional cross-linker
General Description
3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. It is typically coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thiol-disulfide exchange buffered at pH 8.0 (7.5-8.5). Alternately, this reagent may be used as a protected thiolating reagent following initial coupling and reduction of linker. It incorporates four atom linker.
SPDP Preparation Products And Raw materials
Raw materials
Preparation Products
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SPDP Suppliers
- Tel
- 0431-80514535 19917294565
- caoy@chemextension.com
- Country
- China
- ProdList
- 4756
- Advantage
- 58
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- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
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- China
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- 94657
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- 76
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
- Advantage
- 69
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44689
- Advantage
- 61
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9809
- Advantage
- 59
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- +86 (531) 88811783
- Fax
- +86 (531) 55696010 QQ 1762738062
- sales@trio-pharmatech.com (International market)
- Country
- China
- ProdList
- 1856
- Advantage
- 62
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View Lastest Price from SPDP manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- SPDP-NHS ester 68181-17-9
- Price
- US $0.00/g
- Min. Order
- 10g
- Purity
- >99.00%
- Supply Ability
- 10g
- Release date
- 2024-03-27
Career Henan Chemical Co
- Product
- SPDP 68181-17-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 25kg
- Release date
- 2019-07-10
68181-17-9, SPDPRelated Search:
SPDP-PEG4-acid
SPDP-PEG6-NHS ester
SPDP-PEG1-NHS ester
SPDP-PEG3-COOH
SPDP-PEG2-NHS ester
SPDP-PEG6-acid
SPDP-PEG4-NHS ester
SPDP-PEG3-NHS ester
SPDP-PEG8-acid
SPDP-PEG8-NHS ester
N-Hydroxysuccinimide
2-Pyridinethione
Pyridinium acetate
N,N-Diethylhydroxylamine
N-Acetoxysuccinimide
Acetohydroxamic acid
Succinimide
Argon