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DCEBIO

Product Name
DCEBIO
CAS No.
60563-36-2
Chemical Name
DCEBIO
Synonyms
DCEBIO;Potassium Channel,KcsA,DCEBIO,inhibit,Inhibitor;5,6-DICHLORO-1-ETHYL-1H-BENZO[D]IMIDAZOL-2(3H)-ONE;5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE;5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE;2H-Benzimidazol-2-one, 5,6-dichloro-1-ethyl-1,3-dihydro-
CBNumber
CB1308237
Molecular Formula
C9H8Cl2N2O
Formula Weight
231.08
MOL File
60563-36-2.mol
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DCEBIO Property

Melting point:
205-207 °C(Solv: ethyl acetate (141-78-6))
Density 
1.412±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
DMSO: >10mg/mL
form 
solid
pka
10.28±0.30(Predicted)
color 
off-white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D9190
Product name
DCEBIO
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$200
Updated
2024/03/01
Sigma-Aldrich
Product number
D9190
Product name
DCEBIO
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$770
Updated
2023/06/20
Cayman Chemical
Product number
29426
Product name
DCEBIO
Packaging
5mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
29426
Product name
DCEBIO
Packaging
10mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
29426
Product name
DCEBIO
Packaging
25mg
Price
$268
Updated
2024/03/01
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DCEBIO Chemical Properties,Usage,Production

Description

DCEBIO, a derivative of 1-EBIO, is an extremely potent activator of Cl- secretion in T84 colonic cells. DCEBIO stimulates Cl- secretion via the activation of hIK1 K+ channels and the activation of an apical membrane Cl- conductance. 

Uses

DCEBIO is a small Ca2+sensitive K+ channel (SKCa) agonist. It also stimulate nitric oxide (NO) synthesis and vasodilation in resistance arteries.

Definition

ChEBI: DCEBIO is a dichlorobenzene.

Biological Activity

Stimulates Cl - secretion via activation of hIK1 K + channels and the activation of an apical Cl - conductance. More potent than its analog 1-EBIO (1-Ethyl-2-benzimidazolinone ).

storage

Store at RT

DCEBIO Preparation Products And Raw materials

Raw materials

Preparation Products

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DCEBIO Suppliers

EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87

60563-36-2, DCEBIORelated Search:


  • DCEBIO
  • 5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE
  • 5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE
  • 5,6-DICHLORO-1-ETHYL-1H-BENZO[D]IMIDAZOL-2(3H)-ONE
  • 2H-Benzimidazol-2-one, 5,6-dichloro-1-ethyl-1,3-dihydro-
  • Potassium Channel,KcsA,DCEBIO,inhibit,Inhibitor
  • 60563-36-2
  • C9H8N2OCl2
  • Chloride Channel Modulators
  • Voltage-gated Ion Channels
  • Monovalent Ion Channels
  • Ion Channels
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Potassium channel