ChemicalBook > CAS DataBase List > GUANETHIDINE HEMISULFATE

GUANETHIDINE HEMISULFATE

Product Name
GUANETHIDINE HEMISULFATE
CAS No.
60-02-6
Chemical Name
GUANETHIDINE HEMISULFATE
Synonyms
GUANETHIDINE SULFATE;guanethidine sulphate;Iporal;octadin;su-5864;Oktadin;octadine;Guethine;isobarin;nsc-29863
CBNumber
CB1309441
Molecular Formula
C10H22N4.1/2H2O4S
Formula Weight
494.7
MOL File
60-02-6.mol
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GUANETHIDINE HEMISULFATE Property

Melting point:
255-265°C
Density 
1.1052 (rough estimate)
refractive index 
1.7400 (estimate)
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White
Merck 
4560
Stability:
Hygroscopic
CAS DataBase Reference
60-02-6
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Safety

Safety Statements 
24/25
RTECS 
MF3240000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
G815000
Product name
GuanethidineHemisulfate
Packaging
250mg
Price
$70
Updated
2021/12/16
ApexBio Technology
Product number
A8443
Product name
GuanethidineSulfate
Packaging
1g
Price
$80
Updated
2021/12/16
ApexBio Technology
Product number
A8443
Product name
GuanethidineSulfate
Packaging
5g
Price
$240
Updated
2021/12/16
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GUANETHIDINE HEMISULFATE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Ismelin,Ciba,US,1960

Uses

Antihypertensive; antiglaucoma

Definition

ChEBI: A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Manufacturing Process

13.6 grams of chloroacetyl guanide is added while stirring to a solution of 22.6 grams of heptamethylene imine in 200 ml of benzene. After warming for 1 hour, and then cooling, the solution is filtered and the filtrate concentrated under reduced pressure. The residue, containing the 2-(1-N,N-heptamethylene-imino)-aceticacid guanide, is suspended in tetrahydrofuran and added to a refluxing solution of 6 grams of lithium aluminum hydride in tetrahydrofuran. After completion of the reaction, the excess of lithium aluminum hydride is decomposed by adding water, then aqueous sodium hydroxide. The solid material is filtered off, the filtrate is acidified with sulfuric acid and the 2-(1-N,N-heptamethylene-imino)-ethyl-guanidine sulfate can be recovered and recrystallized from aqueous ethanol, MP 276° to 281°C (with decomposition).

Therapeutic Function

Antihypertensive

GUANETHIDINE HEMISULFATE Preparation Products And Raw materials

Raw materials

Preparation Products

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GUANETHIDINE HEMISULFATE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
SHANDONG ZHI SHANG CHEMICAL CO.LTD
Tel
+86 18953170293
Fax
+86 0531-67809011
Email
sales@sdzschem.com
Country
China
ProdList
2930
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652,+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52849
Advantage
58
Suizhou Jiake Biological Engineering Co., Ltd.
Tel
0722-3632989 18008664499
Fax
0722-3255139
Email
2286801987@qq.com
Country
China
ProdList
103
Advantage
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MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
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LGC Science (Shanghai) Ltd.
Tel
17717235263
Email
cindy.yang@lgcgroup.com
Country
China
ProdList
15583
Advantage
58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
4997
Advantage
58
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View Lastest Price from GUANETHIDINE HEMISULFATE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
guanethidine sulfate 60-02-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

60-02-6, GUANETHIDINE HEMISULFATERelated Search:


  • guanetidinsulfate
  • isobarin
  • nsc-29863
  • octadin
  • octadine
  • octatensin
  • su-5864
  • Guanidine, N-[2-(hexahydro-1(2H)-azocinyl)ethyl]-, sulfate (2:1)
  • Guethine
  • Iporal
  • N-[2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine Sulfate
  • Oktatenzin
  • 2-(1-N,N-HEPTAMETHYLENEIMINO)ETHYLGUANIDINE HEMISULFATE
  • 2-(1'-AZACYCLOOCTYL)ETHYLGUANIDINE HEMISULFATE
  • ISMELIN SULFATE
  • GUANETHIDINE SULFATE
  • GUANETHIDINE HEMISULFATE
  • guanethidine sulphate
  • 2-(1'-Azacyclooctyl)ethylguanidinesulfate
  • 2-(1-N,N-Heptamethyleneimino)ethylguanidinesulfate
  • Guanidine, 2-(hexahydro-1(2H)-azocinyl)ethyl-, sulfate (2:1)
  • GUANETHIDINEHEMISULPHATE
  • .Beta.-1-Azacyclooctylethylguanidine
  • Octatensin sulfate
  • Oktadin
  • Sanotensin
  • (2-(hexahydro-1(2h)-azocinyl)ethyl)guanidinesulfate
  • (2-(hexahydro-1(2h)-azocinyl)ethyl)-guanidinsulfate
  • (2-(hexahydro-1(2h)-azocinyl)ethyl)-guanidinsulfate(2:1)
  • (2-(octahydro-1-azocinyl)ethyl)guanidinesulfate
  • (2-(octahydro-1-azocinyl)ethyl)-guanidinsulfate(2:1)
  • 1-(2-guanidinoethyl)octahydro-azocinsulfate(2:1)
  • beta-1-azacyclooctylethylguanidinesulfate
  • guanethidinebisulfate
  • 60-02-6
  • 1960-02-06
  • C20H44N8
  • C10H22N405H2SO4
  • C20H44N8H2SO4
  • C20H46N8O4S
  • C10H22N412H2SO4
  • C10H22N42H2SO4
  • C10H22N412H2O4S
  • C20H44N8H2O4S
  • Amines
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals