R-IMPP

Product Name: R-IMPP
CAS No.: 2133832-83-2
Chemical Name: R-IMPP
Synonyms: R-IMPP;PF-00932239 (R-IMPP);Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-;(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide;Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases
CBNumber: CB13155117
Molecular Formula: C24H27N3O2
Formula Weight: 389.49
MOL File: 2133832-83-2.mol

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R-IMPP Property

Boiling point:: 594.4±50.0 °C(Predicted)
Density: 1.186±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 1 mg/ml; DMSO: 10 mg/ml
form: A crystalline solid
pka: 9.14±0.10(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20861
Product name: (R)-IMPP
Packaging: 1mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 20861
Product name: (R)-IMPP
Packaging: 25mg
Price: $1075
Updated: 2024/03/01

Cayman Chemical

Product number: 20861
Product name: (R)-IMPP
Packaging: 5mg
Price: $288
Updated: 2024/03/01

Cayman Chemical

Product number: 20861
Product name: (R)-IMPP
Packaging: 10mg
Price: $539
Updated: 2024/03/01

ChemScene

Product number: CS-7579
Product name: R-IMPP
Purity: 99.36%
Packaging: 5mg
Price: $100
Updated: 2021/12/16

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R-IMPP Chemical Properties,Usage,Production

Description

(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC₅₀ = 4.8 μM). It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels. (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of PCSK9 translation.

R-IMPP Preparation Products And Raw materials

Raw materials

Preparation Products

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R-IMPP Suppliers

China 28 India 1 United States 7 Global 36

MedChemexpress LLC

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Shanghai EFE Biological Technology Co., Ltd.

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Tianjin Kailiqi Biotechnology Co., Ltd.

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Shanghai Chaolan Chemical Technology Center

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Medi-tech Bioscientific Co., Ltd.

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Angel Pharmatech, Ltd.

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Zhengzhou Acme Chemical Co., Ltd.

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Guangzhou Tomums Life Science Co., Ltd.

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TargetMol Chemicals Inc.

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InvivoChem

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2133832-83-2, R-IMPPRelated Search:

R-IMPP

Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-

PF-00932239 (R-IMPP)

(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide

Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases

2133832-83-2