Diclazuril

Description References

Product Name: Diclazuril
CAS No.: 101831-37-2
Chemical Name: Diclazuril
Synonyms: Qiujia;Nuoqiu;Vecoxan;R-64433;CLINACOX;clinazox;iclazuril;DICLAZUTIL;DICLAZURIL;To g beads
CBNumber: CB1317293
Molecular Formula: C17H9Cl3N4O2
Formula Weight: 407.64
MOL File: 101831-37-2.mol

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Diclazuril Property

Melting point:: 290.5°
Density: 1.56±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:5): 0.16mg/mL
pka: 5.89±0.20(Predicted)
form: Solid
color: White to Light yellow to Light orange
Merck: 14,3080
InChI: InChI=1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)
InChIKey: ZSZFUDFOPOMEET-UHFFFAOYSA-N
SMILES: C1(C=C(C(C(C#N)C2=CC=C(Cl)C=C2)=C(Cl)C=1)Cl)N1N=CC(=O)NC1=O
LogP: 2.439 (est)
CAS DataBase Reference: 101831-37-2(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 2
RTECS: CY1697600
HS Code: 29336990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 34057
Product name: Diclazuril
Purity: VETRANAL?, analytical standard
Packaging: 100mg
Price: $113
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1188560
Product name: Diclazuril
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $436
Updated: 2024/03/01

TCI Chemical

Product number: D5457
Product name: Diclazuril
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $53
Updated: 2024/03/01

TCI Chemical

Product number: D5457
Product name: Diclazuril
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $262
Updated: 2024/03/01

Cayman Chemical

Product number: 27047
Product name: Diclazuril
Packaging: 5g
Price: $68
Updated: 2024/03/01

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Diclazuril Chemical Properties,Usage,Production

Description

Diclazuril (molecular formula: C17H9Cl3N4O2, Trade name: Vecoxan) belongs to a kind of coccidiostat and potent antiprotozoal agents. It is mainly used for the treatment, control, prevention and improvements of Coccidal infections. It alleviates the symptoms of the patients by interrupting the life cycle of the parasites. It induces the morphological changes and attenuates the mitochondrial transmembrane potential in meroites. It can prevent congenital toxoplasmosis and have anticoccidial effects in vivo. It is active through oral administration.

References

http://www.tabletwise.com/medicine/diclazuril
https://en.wikipedia.org/wiki/Diclazuril
http://www.abcam.com/diclazuril-ab143604.html

Chemical Properties

Light yellow or off-white powder, almost insoluble in water, slightly soluble in ethanol, ether, soluble in N,N-2 methylformamide (DMF), dimethylsulfone (DMSO), tetrahydrofuran (THF).

Uses

Diclazuril is a triazinone antiprotozoal that Nucleotide analog with broad-spectrum anticoccidial activity. It has a control effect on a variety of coccidiosis, and is used to prevent coccidiosis in chickens, ducks, quails, turkeys, geese and rabbits.

Definition

ChEBI: 2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile is a nitrile.

Application

Diclazuril is a less toxic, orally administered triazine antiprotozoal. It is widely used in veterinary medicine as a feed additive and veterinary drug. It is registered for oral use in broilers and lambs. Its use in cats (one dose of 25 mg/kg BW) is off-label only. It may be used clinically for the treatment of bovine protozoa. It is also used for the treatment of equine protozoan spinal cord encephalitis (EPM) caused by neuronal sarcocysts.

Veterinary Drugs and Treatments

Diclazuril is a coccidiostat. It is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona and as a coccidiostat in broiler chickens. Diclazuril could potentially be useful in treating coccidiosis, Neospora caninum and Toxoplasma infections in dogs or cats.

Diclazuril Preparation Products And Raw materials

Raw materials

Preparation Products

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Diclazuril Suppliers

Americas 1 Argentina 1 Canada 1 China 402 Europe 3 Germany 2 India 16 Japan 4 South Korea 1 Switzerland 2 United Kingdom 8 United States 31 Global 472

Shandong Jihao Biotechnology Co., Ltd.

Tel: 0531-69958659 15668363232
Email: 8598038@qq.com
Country: China
ProdList: 45
Advantage: 58

Hebei Zhongbei Jiamei Biological Technology Co., Ltd.

Tel: 0311-89171450 15373918792
Email: 3265217077@qq.com
Country: China
ProdList: 45
Advantage: 58

Wuhan Qixinhui Technology Co., Ltd

Tel: 027-87002654 18062710658
Email: 554831559@qq.com
Country: China
ProdList: 934
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8418
Advantage: 55

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9809
Advantage: 59

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

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View Lastest Price from Diclazuril manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Diclazuril 101831-37-2
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-22

Henan Suikang Pharmaceutical Co.,Ltd.

Product: Diclazuril 101831-37-2
Price: US $0.00/kg
Min. Order: 5kg
Purity: ≥96.0%
Supply Ability: 1tons
Release date: 2024-04-26

HebeiShuoshengImportandExportco.,Ltd

Product: Diclazuril 101831-37-2
Price: US $6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000KG/Month
Release date: 2024-08-02

101831-37-2, DiclazurilRelated Search:

Diethylstilbestrol DIOXOPROMETHAZINE HCL Diphenylacetonitrile Dichloroacetic acid 1,4-Dioxane 4-Methoxybenzyl cyanide Selenium dioxide 3,5-DICHLOROPHENYLHYDRAZINE 3,5-Dichlorophenylhydrazine hydrochloride (4-AMINOPHENYL)PHENYLACETONITRILE HYDROCHLORIDE,97% Benzeneacetonitrile Clazuril (4-ETHYL-PHENYL)-HYDRAZINE 2,6-Dichlorobenzyl acetonitrile 4-Isopropylphenylhydrazine hydrochloride 4-Ethylphenylhydrazine hydrochloride 4-AMINO-2-CHLORODIPHENYLACETONITRILE Chlorobenzene

2,6-Dichloro-a-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrile

Nuoqiu

Vecoxan

2-[3,5-Dichloro-4-(α-cyano-4-chlorobenzyl)phenyl]-1,2,4-triazine-3,5(2H,4H)-dione

2-[4-(4-Chloro-α-cyanobenzyl)-3,5-dichlorophenyl]-1,2,4-triazine-3,5(2H,4H)-dione

CLINACOX

DICLAZURIL

DICLAZUTIL

Diclazuril premix 0.5%,1%

Diclazuril 0.5% 1% premix

Qiujia

DiclazurilCpv2000

clinazox

R-64433

2,6-dichloro-α-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3h)-yl]benzeneacetonitrile

Diclazuril 101831-37-2

2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile

iclazuril

Diclazuril 0

Diclazuril (200 mg)

2,6-Dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-

Diclazuril HOUSE STANDARD

Soluble Diclazuril

Diclazuril premixes

2,6-DICHLORO-A-(4-CHLOROPHENYL)-4(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN-2-YL)BENZENEACETONITRILE

2,6-DICHLORO-ALPHA-(4-CHLOROPHENYL)-4-(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN-2 (3H)-YL)BENZENEACETONITRILE

2,6-dichloro-alpha-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3h)-yl)benzeneacetonitrile

(4-chlorophenyl)[2,6-dichloro-3-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl]acetonitrile

(4-chlorophenyl)[2,6-dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl]acetonitrile

Diclazuril for system suitability CRS

Diclazuril powder

Benzeneacetonitrile, 2,6-dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-

Diclazuril solution in Acetonitrile/DMF, 1000μg/mL

2-(4-Chlorophenyl)-2-(2,6-dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetonitrile

2,6-Dichloro-alpha-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrile

Diclazuril USP/EP/BP

DICLAZURIL PREMIX 0.5%

DiclazurilQ: What is Diclazuril Q: What is the CAS Number of Diclazuril Q: What is the storage condition of Diclazuril Q: What are the applications of Diclazuril

Diclazuril (1188560)

To g beads

Diclozuril

3'-FLUORO-54'-(TRIFLUOROMETHYL)ACETOPHENONE

DiclazurilSoiuble

Diclazuril in DMSO

C12533000 Diclazuril

Diclazuril in Methanol:DMF=1:1

Sildenafil Impurity 76-d3

101831-37-2

831-37-2

C17H9Cl3N4O2

Pharmaceuticals

Aromatics

Bases & Related Reagents

Heterocycles

Intermediates & Fine Chemicals

Nucleotides

Veterinaries

101831-37-2