ChemicalBook > CAS DataBase List > 4-AMINO-PYRIDIN-2-OL

4-AMINO-PYRIDIN-2-OL

Product Name
4-AMINO-PYRIDIN-2-OL
CAS No.
38767-72-5
Chemical Name
4-AMINO-PYRIDIN-2-OL
Synonyms
4-aminopyridin-2(1H)-one;3-DEAZACYTOSINE;4-AMINO-2-PYRIDONE;4-AMino-2-pyridinol;4-AMINO-PYRIDIN-2-OL;4-amipyridin-2(1H)-one;4-AMino-1H-pyridin-2-one;4-amino-2(1H)-Pyridinone;4-Aminopyridin-2-ol 97%;4-Amino-2-hydroxy prydine
CBNumber
CB1322509
Molecular Formula
C5H6N2O
Formula Weight
110.11
MOL File
38767-72-5.mol
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4-AMINO-PYRIDIN-2-OL Property

Melting point:
219-221 °C(Solv: acetone (67-64-1))
Boiling point:
310.7±35.0 °C(Predicted)
Density 
1.208±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
solid
pka
11.49±0.10(Predicted)
Appearance
White to light brown Solid
CAS DataBase Reference
38767-72-5
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A629020
Product name
4-Amino-2-pyridone
Packaging
1g
Price
$165
Updated
2021/12/16
Apolloscientific
Product number
OR929418
Product name
4-Amino-1H-pyridin-2-one
Packaging
1g
Price
$26
Updated
2021/12/16
AK Scientific
Product number
J50743
Product name
4-Amino-2-hydroxypyridine
Packaging
1g
Price
$30
Updated
2021/12/16
AK Scientific
Product number
W5935
Product name
4-Amino-2-hydroxypyridine
Packaging
1g
Price
$41
Updated
2021/12/16
Matrix Scientific
Product number
068405
Product name
4-Amino-1H-pyridin-2-one
Purity
>95%
Packaging
1g
Price
$74
Updated
2021/12/16
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4-AMINO-PYRIDIN-2-OL Chemical Properties,Usage,Production

Uses

4-Amino-2-pyridone is used in the preparation of nucleoside analogues with antitumor and antiviral activity.

Synthesis

14432-12-3

38767-72-5

General procedure for the synthesis of 4-aminopyridin-2-one from 2-chloro-4-aminopyridine: A mixture of 2-chloro-4-aminopyridine (127 mg, 1.0 mmol) and potassium hydroxide (280.6 mg, 5.0 mmol) in toluene (4.0 mL) was heated in a sealed tube and reacted for 72 hr at 170 °C. Upon completion of the reaction, the mixture was cooled to room temperature and the toluene solvent was subsequently removed by distillation under reduced pressure. The residue was purified by rapid chromatography on silica gel (eluent ratio dichloromethane/methanol/ammonia: 78/20/2) to afford the target product 4-aminopyridin-2-one (107 mg, 97% yield) as a light yellow solid.

References

[1] Synlett, 2016, vol. 27, # 1, p. 67 - 69
[2] Tetrahedron, 1999, vol. 55, # 41, p. 11985 - 11996

4-AMINO-PYRIDIN-2-OL Preparation Products And Raw materials

Raw materials

Preparation Products

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4-AMINO-PYRIDIN-2-OL Suppliers

Canada 1 China 152 Germany 2 India 3 Japan 2 Switzerland 1 United Kingdom 5 United States 21 Global 187
Matrix Fine Chemicals GmbH
Tel
--
Fax
--
Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58
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View Lastest Price from 4-AMINO-PYRIDIN-2-OL manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-AMino-1H-pyridin-2-one 38767-72-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-09
Hebei Chuanghai Biotechnology Co., Ltd
Product
4-AMINO-PYRIDIN-2-OL 38767-72-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-12
Dideu Industries Group Limited
Product
4-AMINO-PYRIDIN-2-OL 38767-72-5
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-09-24

38767-72-5, 4-AMINO-PYRIDIN-2-OLRelated Search:

5-AMINO-PYRIDIN-3-OL,97%,5-AMINO-PYRIDIN-3-OL 2-AMINO-PYRIDIN-3-OL,2-AMINO-3-HYDROXYPYRIDINE 2-AMINO-PYRIDIN-3-OL 3,4-Diamino-2-hydroxypyridine 4,5-DIAMINO-6-HYDROXYPYRIMIDINE SULFATE 5,6-DICHLORONICOTINIC ACID ETHYL ESTER 5-AMINO-PYRIDIN-2-OL 6-AMINO-PYRIDIN-3-OL,6-Amino-pyridin-3-ol hydrobromide 6-AMINO-PYRIDIN-2-OL 3-AMINO-PYRIDIN-2-OL 6-AMINO-PYRIDIN-3-OL HYDROCHLORIDE 2-AMINO-PYRIDIN-4-OL 4,5-Diamino-2-pyridinol 4-AMINO-PYRIDIN-3-OL,4-Amino-pyridin-3-ol HBr 3-Amino-2(1H)-pyridinone Fluroxypyr 4-Amino-2-ethoxypyridine Starane 3-Amino-4-pyridinol

  • 3-DEAZACYTOSINE
  • 3-Deazacytosine 4-Amino-2-pyridone
  • 4-Amino-2-hydroxy prydine
  • 4-AMINO-PYRIDIN-2-OL
  • 4-AMINO-2-PYRIDONE
  • 4-AMINO-2-HYDROXYPYRIDINE
  • 4-AMINO-2-HYDROXYPYRIDINE 98%
  • 2(1H)-Pyridinone, 4-amino-
  • 4-aminopyridin-2(1H)-one
  • 4-amino-2(1H)-Pyridinone
  • 4-AMino-1H-pyridin-2-one
  • 4-AMino-2-pyridinol
  • 2-Hydroxy-4-aMinopyridine
  • 4-amino-1,2-dihydropyridin-2-one
  • 2-Pyridinol,4-Amino- (8Ci
  • 4-AMINO-PYRIDIN-2-OL ISO 9001：2015 REACH
  • 4-amipyridin-2(1H)-one
  • 4-Aminopyridin-2-ol 97%
  • 38767-72-5
  • API intermediates
  • Pyridines
  • pharmacetical
  • Pyridine
  • Heterocycle-Pyridine series
  • Nitrogen cyclic compounds