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2-Ethyl-4-methylimidazole

Product Name
2-Ethyl-4-methylimidazole
CAS No.
931-36-2
Chemical Name
2-Ethyl-4-methylimidazole
Synonyms
2E4MZ;2-ETHYL-4-METHYL-1H-IMIDAZOLE;2E4MI;EMI24;Ethyl-4-MethyliMidaz;LABOTEST-BB LTBB000689;2-ethyl-4-methyl-1h-imidazol;2-Ethyl-5-methyl-1H-imidazole;1H-Imidazole,2-ethyl-4-methyl-;EMI-70
CBNumber
CB1325025
Molecular Formula
C6H10N2
Formula Weight
110.16
MOL File
931-36-2.mol
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2-Ethyl-4-methylimidazole Property

Melting point:
47-54 °C (lit.)
Boiling point:
292-295 °C (lit.)
Density 
0.975 g/mL at 25 °C (lit.)
vapor pressure 
0.028Pa at 20℃
refractive index 
n20/D 1.5(lit.)
Flash point:
280 °F
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to lump to clear liquid
pka
15.32±0.10(Predicted)
Specific Gravity
0.975
color 
White or Colorless to Yellow to Orange
Water Solubility 
210 g/L (20 ºC)
BRN 
1711
InChIKey
ULKLGIFJWFIQFF-UHFFFAOYSA-N
LogP
1.13 at 25℃
CAS DataBase Reference
931-36-2(CAS DataBase Reference)
NIST Chemistry Reference
1H-Imidazole, 2-ethyl-4-methyl-(931-36-2)
EPA Substance Registry System
2-Ethyl-4-methylimidazole (931-36-2)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-41
Safety Statements 
26-39
WGK Germany 
2
RTECS 
NI6147500
10
Hazard Note 
Irritant/Harmful
TSCA 
Yes
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E36652
Product name
2-Ethyl-4-methylimidazole
Purity
95%
Packaging
5g
Price
$45.03
Updated
2025/07/31
Sigma-Aldrich
Product number
E36652
Product name
2-Ethyl-4-methylimidazole
Purity
95%
Packaging
100g
Price
$79.9
Updated
2025/07/31
TCI Chemical
Product number
E0232
Product name
2-Ethyl-4-methylimidazole
Purity
>95.0%(GC)
Packaging
25g
Price
$33
Updated
2025/07/31
TCI Chemical
Product number
E0232
Product name
2-Ethyl-4-methylimidazole
Purity
>95.0%(GC)
Packaging
100g
Price
$87
Updated
2025/07/31
TCI Chemical
Product number
E0232
Product name
2-Ethyl-4-methylimidazole
Purity
>95.0%(GC)
Packaging
500g
Price
$321
Updated
2025/07/31
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2-Ethyl-4-methylimidazole Chemical Properties,Usage,Production

Chemical Properties

clear yellow viscous liquid after melting

Uses

Curing epoxy-resin systems.

Uses

2-Ethyl-4-methylimidazole can be used as a:

  • cross-linker for epoxy resins to synthesize network polymers with improved thermal resistance and physical properties.
  • curing agent for polysiloxane episulfide resin (PSER).
  • catalyst to promote curing of blends of hyperbranched aromatic epoxy polymer and bisphenol F diglycidyl ether.

Definition

ChEBI: 5K8XI641G3 is a member of imidazoles.

Application

2-Ethyl-4-methylimidazole is an important synthetic intermediate. It is used as an intermediate in pharmaceuticals, agrochemicals, dyes, textile auxiliaries, pigments and other organic chemicals. It can be used as a basic ingredient in other active ingredients, as a catalyst in chemical reactions, and in the curing of epoxy resins.

Preparation

2-Ethyl-4-methylimidazole was prepared as follows: diamine and propionitrile have a cyclization reaction sequentially at the temperature of 80-110 °C and 120-140 °C under the catalysis of a catalyst; a product after the cyclization reaction has a dehydrogenation reaction through raney nickel at the temperature of 170-200 °C, and 2-ethyl-4-methylimidazole is obtained.

Flammability and Explosibility

Non flammable

Synthesis

931-35-1

931-36-2

Dehydrogenation reaction: 550 g of 2-ethyl-4-methylimidazole dihydrochloride was placed in a three-necked flask fitted with an electric stirring device. Preparation of Ruanne nickel catalyst: 22 g of Ruanne nickel was added to 60 mL of 20 wt% potassium hydroxide aqueous solution and stirred for 15 min, followed by washing with pure water and ethanol. The prepared nickel ruanne catalyst was added to the reaction system. The reaction system was heated in an oil bath, the temperature was controlled to 190°C, and the reaction was continuously stirred for 3.5 hours. Upon completion of the reaction, the reaction solution was left to clarify, and the upper layer of clarified liquid was separated and removed. The residue was diluted with a small amount of toluene and filtered to remove the Nguyenay Ni catalyst. The filtrates were combined and vacuum distilled. Fractions with boiling points of 150-160°C/10 mmHg were collected to give 488 g of 2-ethyl-4-methylimidazole in 90.4% yield. The product was analyzed by gas chromatography and the purity was greater than 97%.

References

[1] Patent: CN105367499, 2016, A. Location in patent: Paragraph 0019; 0029; 0031; 0032; 0033

2-Ethyl-4-methylimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Ethyl-4-methylimidazole Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
K. Sakai & Co., Ltd.
Tel
--
Fax
--
Email
em@ksakai.co.jp
Country
Japan
ProdList
957
Advantage
58
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
Junsei Chemical Co., Ltd.
Tel
--
Fax
--
Email
shiyaku@junsei.co.jp
Country
Japan
ProdList
3096
Advantage
46
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View Lastest Price from 2-Ethyl-4-methylimidazole manufacturers

Hebei Fengjia New Material Co., Ltd
Product
2-Ethyl-4-methylimidazole 931-36-2
Price
US $3.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 tons
Release date
2024-08-22
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Ethyl-4-methylimidazole 931-36-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-13
HebeiShuoshengImportandExportco.,Ltd
Product
2-Ethyl-4-methylimidazole 931-36-2
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08

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