Belizatinib

ChemicalBook > CAS DataBase List > Belizatinib

Product Name: Belizatinib
CAS No.: 1357920-84-3
Chemical Name: Belizatinib
Synonyms: CS-2493;TSR-011;Belizatinib;Belizatinib (TSR011);Belizatinib, 10 mM in DMSO;TSR011; TSR011; TSR 011; BELIZATINIB;4-Fluoro-N-(6-((4-(2-hydroxypropan-2-yl)piperidin-1-yl)methyl)-1-(cis-4-(isopropylcarbamoyl)cyclohexyl)-1H-benzo[d]imidazol-2-yl)benzamide;Benzamide, 4-fluoro-N-[6-[[4-(1-hydroxy-1-methylethyl)-1-piperidinyl]methyl]-1-[cis-4-[[(1-methylethyl)amino]carbonyl]cyclohexyl]-1H-benzimidazol-2-yl]-;TSR011,Trk Receptor,CD246,ALK tyrosine kinase receptor,Tropomyosin related kinase receptor,TSR 011,inhibit,Cluster of differentiation 246,Belizatinib,Inhibitor,Anaplastic lymphoma kinase,Anaplastic lymphoma kinase (ALK)
CBNumber: CB13333605
Molecular Formula: C33H44FN5O3
Formula Weight: 577.73
MOL File: 1357920-84-3.mol

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Belizatinib Property

Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF:30.0(Max Conc. mg/mL);51.93(Max Conc. mM)
DMSO:143.33(Max Conc. mg/mL);248.08(Max Conc. mM)
Ethanol:65.0(Max Conc. mg/mL);112.5(Max Conc. mM)
form: A crystalline solid
pka: 12.55±0.43(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28458
Product name: Belizatinib
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 28458
Product name: Belizatinib
Packaging: 25mg
Price: $485
Updated: 2024/03/01

Cayman Chemical

Product number: 28458
Product name: Belizatinib
Packaging: 5mg
Price: $151
Updated: 2024/03/01

Cayman Chemical

Product number: 28458
Product name: Belizatinib
Packaging: 10mg
Price: $249
Updated: 2024/03/01

AK Scientific

Product number: 3366DN
Product name: Belizatinib
Packaging: 10mg
Price: $374
Updated: 2021/12/16

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Belizatinib Chemical Properties,Usage,Production

Description

Belizatinib, also known as TSR-011, is an oral inhibitor of ALK and TRK.

Description

Belizatinib is an inhibitor of anaplastic lymphoma kinase (ALK) and tropomyosin-related kinases A/B/C (IC₅₀s = 0.7 and <3 nM, respectively).

Uses

Belizatinib is used in treating diseases via targeted modulation of gene signaling networks.

Belizatinib Preparation Products And Raw materials

Raw materials

Preparation Products

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Belizatinib Suppliers

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1357920-84-3, BelizatinibRelated Search:

TTP 22 TTK21 TTNPB (Arotinoid Acid)

Belizatinib

Belizatinib (TSR011)

TSR-011

CS-2493

TSR011; TSR011; TSR 011; BELIZATINIB

Benzamide, 4-fluoro-N-[6-[[4-(1-hydroxy-1-methylethyl)-1-piperidinyl]methyl]-1-[cis-4-[[(1-methylethyl)amino]carbonyl]cyclohexyl]-1H-benzimidazol-2-yl]-

TSR011,Trk Receptor,CD246,ALK tyrosine kinase receptor,Tropomyosin related kinase receptor,TSR 011,inhibit,Cluster of differentiation 246,Belizatinib,Inhibitor,Anaplastic lymphoma kinase,Anaplastic lymphoma kinase (ALK)

4-Fluoro-N-(6-((4-(2-hydroxypropan-2-yl)piperidin-1-yl)methyl)-1-(cis-4-(isopropylcarbamoyl)cyclohexyl)-1H-benzo[d]imidazol-2-yl)benzamide

Belizatinib, 10 mM in DMSO

1357920-84-3

C33H44FN5O3