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Belizatinib

Product Name
Belizatinib
CAS No.
1357920-84-3
Chemical Name
Belizatinib
Synonyms
CS-2493;TSR-011;Belizatinib;Belizatinib (TSR011);TSR011; TSR011; TSR 011; BELIZATINIB;4-Fluoro-N-(6-((4-(2-hydroxypropan-2-yl)piperidin-1-yl)methyl)-1-(cis-4-(isopropylcarbamoyl)cyclohexyl)-1H-benzo[d]imidazol-2-yl)benzamide;Benzamide, 4-fluoro-N-[6-[[4-(1-hydroxy-1-methylethyl)-1-piperidinyl]methyl]-1-[cis-4-[[(1-methylethyl)amino]carbonyl]cyclohexyl]-1H-benzimidazol-2-yl]-;TSR011,Trk Receptor,CD246,ALK tyrosine kinase receptor,Tropomyosin related kinase receptor,TSR 011,inhibit,Cluster of differentiation 246,Belizatinib,Inhibitor,Anaplastic lymphoma kinase,Anaplastic lymphoma kinase (ALK)
CBNumber
CB13333605
Molecular Formula
C33H44FN5O3
Formula Weight
577.73
MOL File
1357920-84-3.mol
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Belizatinib Property

Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF:30.0(Max Conc. mg/mL);51.93(Max Conc. mM)
DMSO:143.33(Max Conc. mg/mL);248.08(Max Conc. mM)
Ethanol:65.0(Max Conc. mg/mL);112.5(Max Conc. mM)
form 
A crystalline solid
pka
12.55±0.43(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28458
Product name
Belizatinib
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
28458
Product name
Belizatinib
Packaging
25mg
Price
$485
Updated
2024/03/01
Cayman Chemical
Product number
28458
Product name
Belizatinib
Packaging
5mg
Price
$151
Updated
2024/03/01
Cayman Chemical
Product number
28458
Product name
Belizatinib
Packaging
10mg
Price
$249
Updated
2024/03/01
ChemScene
Product number
CS-6943
Product name
Belizatinib
Purity
99.66%
Packaging
2mg
Price
$60
Updated
2021/12/16
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Belizatinib Chemical Properties,Usage,Production

Description

Belizatinib, also known as TSR-011, is an oral inhibitor of ALK and TRK.

Description

Belizatinib is an inhibitor of anaplastic lymphoma kinase (ALK) and tropomyosin-related kinases A/B/C (IC50s = 0.7 and <3 nM, respectively).

Uses

Belizatinib is used in treating diseases via targeted modulation of gene signaling networks.

Belizatinib Preparation Products And Raw materials

Raw materials

Preparation Products

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Belizatinib Suppliers

China 45 India 1 United States 7 Global 53
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58

1357920-84-3, BelizatinibRelated Search:

TTP 22 TTK21 TTNPB (Arotinoid Acid)

  • Belizatinib
  • Belizatinib (TSR011)
  • TSR-011
  • CS-2493
  • TSR011; TSR011; TSR 011; BELIZATINIB
  • Benzamide, 4-fluoro-N-[6-[[4-(1-hydroxy-1-methylethyl)-1-piperidinyl]methyl]-1-[cis-4-[[(1-methylethyl)amino]carbonyl]cyclohexyl]-1H-benzimidazol-2-yl]-
  • TSR011,Trk Receptor,CD246,ALK tyrosine kinase receptor,Tropomyosin related kinase receptor,TSR 011,inhibit,Cluster of differentiation 246,Belizatinib,Inhibitor,Anaplastic lymphoma kinase,Anaplastic lymphoma kinase (ALK)
  • 4-Fluoro-N-(6-((4-(2-hydroxypropan-2-yl)piperidin-1-yl)methyl)-1-(cis-4-(isopropylcarbamoyl)cyclohexyl)-1H-benzo[d]imidazol-2-yl)benzamide
  • 1357920-84-3
  • C33H44FN5O3