ChemicalBook > CAS DataBase List > ARS-1620
ARS-1620
- Product Name
- ARS-1620
- CAS No.
- 1698055-85-4
- Chemical Name
- ARS-1620
- Synonyms
- CPD1588;ARS-1620;ARS-1620;ARS 1620;ARS1620;inhibit,Ras,Inhibitor,ARS-1620,ARS 1620,ARS1620;(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one;(S)-1-[4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-2-propen-1-one;2-Propen-1-one, 1-[4-[(7S)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-;1-?[4-?[(7S)?-?6-?Chloro-?8-?fluoro-?7-?(2-?fluoro-?6-?hydroxyphenyl)?-?4-?quinazolinyl]?-?1-?piperazinyl]?-?2-?propen-?1-?one
- CBNumber
- CB13369787
- Molecular Formula
- C21H17ClF2N4O2
- Formula Weight
- 430.84
- MOL File
- 1698055-85-4.mol
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ARS-1620 Property
- Boiling point:
- 614.7±55.0 °C(Predicted)
- Density
- 1.434±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:70.0(Max Conc. mg/mL);162.47(Max Conc. mM)
- form
- A solid
- pka
- 6.03±0.35(Predicted)
- color
- Off-white to light yellow
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 27915
- Product name
- ARS1620
- Packaging
- 1mg
- Price
- $118
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27915
- Product name
- ARS1620
- Packaging
- 5mg
- Price
- $351
- Updated
- 2024/03/01
Axon Medchem
- Product number
- Axon3084
- Product name
- ARS-1620
- Purity
- 99%
- Packaging
- 5mg
- Price
- $159.5
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0035119
- Product name
- ARS-1620
- Purity
- 99.20%
- Packaging
- 5mg
- Price
- $250
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0035119
- Product name
- ARS-1620
- Purity
- 99.20%
- Packaging
- 10mg
- Price
- $350
- Updated
- 2021/12/16
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ARS-1620 Chemical Properties,Usage,Production
Uses
ARS-1620, is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.
Definition
ChEBI: ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent.
ARS-1620 Preparation Products And Raw materials
Raw materials
Preparation Products
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ARS-1620 Suppliers
- Tel
- 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 9923
- Advantage
- 65
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6391
- Advantage
- 58
- Tel
- +1-631-485-4226
- Fax
- 1-631-614-7828
- inquiry@bocsci.com
- Country
- United States
- ProdList
- 19553
- Advantage
- 58
- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58
- Tel
- support@targetmol.com
- Country
- United States
- ProdList
- 38631
- Advantage
- 58
- Tel
- --
- Fax
- --
- cayman@caymanchem.com
- Country
- United States
- ProdList
- 6213
- Advantage
- 81
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View Lastest Price from ARS-1620 manufacturers
Career Henan Chemical Co
- Product
- ARS-1620 1698055-85-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-18