2,1,3-Benzoxadiazole-5-carboxylic acid
- Product Name
- 2,1,3-Benzoxadiazole-5-carboxylic acid
- CAS No.
- 19155-88-5
- Chemical Name
- 2,1,3-Benzoxadiazole-5-carboxylic acid
- Synonyms
- BUTTPARK 29\08-25;RARECHEM AL BO 0811;5-Benzofurazancarboxylic acid;BENZOFURAZAN-5-CARBOXYLIC ACID;Benzoxadiazole-5-carboxylic acid;1,2,3-Benzoxadiazole-5-carboxylicacid;2,1,3-BENZOXADIAZOLE-5-CARBOXYLIC ACID;benzo[1,2,5]oxadiazole-5-carboxylic acid;2,1,3-Benzoxadiazole-5-carboxylicacid97%;2,1,3-Benzoxadiazole-5-carboxylic acid 97%
- CBNumber
- CB1337002
- Molecular Formula
- C7H4N2O3
- Formula Weight
- 164.12
- MOL File
- 19155-88-5.mol
2,1,3-Benzoxadiazole-5-carboxylic acid Property
- Melting point:
- 157-160 °C (lit.)
- Boiling point:
- 360.0±34.0 °C(Predicted)
- Density
- 1.558±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder
- pka
- 3.10±0.30(Predicted)
- color
- Yellow
- CAS DataBase Reference
- 19155-88-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 556610
- Product name
- 2,1,3-Benzoxadiazole-5-carboxylic acid
- Purity
- 97% (GC)
- Packaging
- 500mg
- Price
- $94.8
- Updated
- 2023/01/07
- Product number
- B291583
- Product name
- 2,1,3-Benzoxadiazole-5-carboxylic acid
- Packaging
- 250mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FB152051
- Product name
- 2,1,3-Benzoxadiazole-5-carboxylic acid
- Packaging
- 250mg
- Price
- $412.5
- Updated
- 2021/12/16
- Product number
- CHM0019156
- Product name
- 2,1,3-BENZOXADIAZOLE-5-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $606.61
- Updated
- 2021/12/16
- Product number
- CHM0019156
- Product name
- 2,1,3-BENZOXADIAZOLE-5-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $638.62
- Updated
- 2021/12/16
2,1,3-Benzoxadiazole-5-carboxylic acid Chemical Properties,Usage,Production
Chemical Properties
Light yellow powder
Synthesis
6086-24-4
19155-88-5
General procedure for the synthesis of 2,1,3-benzoxadiazole-5-carboxylic acid from benzoxafurazan-5-carboxylic acid: 2,1,3-benzoxadiazole-5-carboxylic acid N-oxide (80 g) was dissolved in anhydrous ethanol (800 ml) in a 2 L reactor fitted with a mechanical stirrer, a thermometer, a dosing funnel, a reflux condenser and a nitrogen inlet. Triethyl phosphite (114.05 g) was slowly added to this solution over a period of 10 minutes at a temperature range of 62°C to 70°C. The reaction mixture was heated to reflux temperature (76-78°C) and maintained for 2 hours. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding reagent ratio of CHCl3:acetone:acetic acid = 100:2:1) to confirm that the reaction was complete. Subsequently, the solvent was evaporated under reduced pressure conditions (30 mbar, 40 °C) to give a black oily product (180 g). To this oily product, water (400 ml) was added and subsequently extracted with ethyl acetate (first 400 ml, second 160 ml). The organic phases were combined and washed with 850 ml of aqueous sodium hydroxide (9.5 μl).
References
[1] Patent: EP2187888, 2015, B1. Location in patent: Paragraph 0087; 0089
[2] MedChemComm, 2015, vol. 6, # 9, p. 1673 - 1678
[3] Journal of Medicinal Chemistry, 1968, vol. 11, # 2, p. 305 - 311
2,1,3-Benzoxadiazole-5-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2,1,3-Benzoxadiazole-5-carboxylic acid Suppliers
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View Lastest Price from 2,1,3-Benzoxadiazole-5-carboxylic acid manufacturers
- Product
- 2,1,3-Benzoxadiazole-5-carboxylic acid 19155-88-5
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-27
- Product
- 2,1,3-Benzoxadiazole-5-carboxylic acid 19155-88-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11