ChemicalBook > CAS DataBase List > Oxygen-fluorine acid

Oxygen-fluorine acid

Product Name
Oxygen-fluorine acid
CAS No.
82419-35-0
Chemical Name
Oxygen-fluorine acid
Synonyms
OFLOXACIN Q ACID;Ofloxacin Carboxylic Acid;Ofloxacin-1;AURORA 21894;Olfoxacin Acid;Oxygen-fluorine;AKOS BBS-00001807;OXYGEN-FLUORINE ACID;OTAVA-BB BB0111050010;DIFLUOROCARBOYLIC ACID
CBNumber
CB9427004
Molecular Formula
C13H9F2NO4
Formula Weight
281.21
MOL File
82419-35-0.mol
More
Less

Oxygen-fluorine acid Property

Melting point:
320-322 °C (lit.)
Boiling point:
459.2±45.0 °C(Predicted)
Density 
1.61±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Heated)
pka
4.87±0.40(Predicted)
color 
Off-White
BRN 
4202751
CAS DataBase Reference
82419-35-0(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
472670
Product name
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
Purity
97%
Packaging
5g
Price
$39.36
Updated
2024/03/01
TCI Chemical
Product number
O0404
Product name
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
Purity
>98.0%(HPLC)
Packaging
5g
Price
$83
Updated
2024/03/01
TCI Chemical
Product number
O0404
Product name
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
Purity
>98.0%(HPLC)
Packaging
25g
Price
$290
Updated
2024/03/01
Usbiological
Product number
009538
Product name
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid|
Packaging
1g
Price
$425
Updated
2021/12/16
TRC
Product number
D445745
Product name
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid(RS-OfloxacinCarboxylicAcid)
Packaging
10g
Price
$255
Updated
2021/12/16
More
Less

Oxygen-fluorine acid Chemical Properties,Usage,Production

Chemical Properties

Grey-Yellow Powder

Uses

9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (Ofloxacin EP Impurity A) is an Ofloxacin intermediate.

General Description

(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid may be used in the preparation of the following:

  • kynurenine aminotransferase II (KAT II) inhibitor, [(S)-(-)-9-(4-aminopiperazine-1-yl)-8-fluoro-3-methyl-6-oxo-2,3,5,6-tetrahydro-4H-1-oxa-3a-aza-phenalene-5-carboxylic acid]
  • fused-ring derivatives
  • N-desmethyllevofloxacin

Oxygen-fluorine acid Preparation Products And Raw materials

Raw materials

Sodium hydride Ethyl 2,3,4,5-tetrafluorobenzoyl acetate Acetic anhydride Potassium hydroxide Triethyl orthoformate DL-Alaninol Tetrahydrofuran Hydrochloric acid Dimethyl sulfoxide

Preparation Products

More
Less

Oxygen-fluorine acid Suppliers

Americas 1 Austria 1 Belgium 2 Canada 2 China 197 Europe 1 Germany 1 India 23 Japan 2 Switzerland 1 Ukraine 1 United Kingdom 6 United States 32 Global 270
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1390
Advantage
62
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5047
Advantage
50
More
Less

View Lastest Price from Oxygen-fluorine acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Oxygen-fluorine acid 82419-35-0
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg
Release date
2021-11-03
Hebei Yanxi Chemical Co., Ltd.
Product
Oxygen-fluorine acid 82419-35-0
Price
US $0.00/kg
Min. Order
1kg
Purity
98.50%
Supply Ability
20tons
Release date
2023-09-14
Henan Fengda Chemical Co., Ltd
Product
Oxygen-fluorine acid 82419-35-0
Price
US $36.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-16

82419-35-0, Oxygen-fluorine acidRelated Search:

Methyl salicylate Dihydromyrcenol 1-AdaMantanethylaMine Oxygen Ofloxacin Levofloxacin Tribenuron methyl Basic Violet 1 Methylparaben Methyl acrylate Kresoxim-methyl Methanol Levofloxacin carboxylic acid Piperazine 1-Piperazinecarbaldehyde 2,3,4,5-Tetrafluorobenzoyl chloride 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 10-amino-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S)- (9CI) Methyl

  • 9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-7H-PYRIDO[1,2,3-DE]-1,4-BENZ-OXAZINE-6-CARBOXYLIC ACID
  • 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxyllic acid
  • 9,10-DIFLUORO-3-METHYL-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLIC ACID
  • AURORA 21894
  • AKOS BBS-00001807
  • OXYGEN-FLUORINE ACID
  • OTAVA-BB BB0111050010
  • 9,10-Difluoro-2,3-Dihydro-3-Methyl-7-Oxo-7h-Pyroido(1,2,3-De)(1,4)Benzoxazine-6-Carboxylic Acid
  • Oxygen fluorine acid(FPA)
  • DIFLUOROCARBOYLIC ACID
  • 9,10-DIFLUORO-2,3-DIHYDRO-3-ME-7-OXO-7H- PYRIDO(1,2,3-DE)1,4-BENZOXAZINE-6-COOH
  • OFLOXACIN Q ACID
  • 9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro 7-H-Pyrido-1,2,3-DE]-1,4-Benzoxyazine-6-Carboxylic Acid
  • Oxygen-fluorine
  • 9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylicacid
  • 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3de]-1,4-benzoxazine
  • 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic
  • (RS)-9,10-Difluro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid (FPA)
  • 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
  • Ofloxacin Impurity 4(Ofloxacin EP Impurity A)
  • 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (RS-Ofloxacin Carboxylic Acid)
  • Ofloxacin EP IMpurity A
  • (RS)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
  • 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-DE]-1,4-benz-oxazine-6-carboxylic acid ,97%
  • 9,10-difluoro-2,3-dihydro-3-me-7-oxo-7h-pyrido-1,
  • Oxygen-fluorine acid ,98%
  • 9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBO
  • 7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLICACID,9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO
  • Olfoxacin Acid
  • Ofloxacin Impurity A(EP)
  • Ofloxacin-1
  • Levofloxacin Hydrochloride ImpurityⅡ: Impurity A(9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (RS-Ofloxacin Carboxylic Acid))
  • Ofloxacin Carboxylic Acid
  • 6,7-Difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
  • RS-Ofloxacin Carboxylic Acid
  • 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid&gt
  • Ofloxacin impurity A CRS
  • (RS)-9,10-Difluoro-3-methyl-7-oxo-2
  • (+/-)9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]lbenzoxazine-6-carboylic acid
  • Ofloxacin EP Impurity A (Ofloxacin Difluoro Carboxylic Acid)
  • Ofloxacin impurity A (O0120010)
  • Levofloxacin Hydrochloride ImpurityⅡ: Impurity A(9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (RS-Ofloxacin Carboxylic Acid))
  • Levofloxacin Hydrochloride ImpurityⅡ: Impurity A(9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid_x000b_(RS-Ofloxacin Carboxylic Acid))
  • Oxygen-fluorineacid Ethambutol dihydrochloride
  • 82419-35-0
  • C13H9F2NO4
  • C13H8F2NO4
  • Heterocyclic Building Blocks
  • Benzoxazines
  • Building Blocks
  • Various Intermediates
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Benzoxazines
  • Building Blocks
  • Heterocyclic Building Blocks
  • OFLOXACIN INTERMIDATE