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Oxygen-fluorine acid

Product Name
Oxygen-fluorine acid
CAS No.
82419-35-0
Chemical Name
Oxygen-fluorine acid
Synonyms
OFLOXACIN Q ACID;Ofloxacin Carboxylic Acid;Ofloxacin-1;AURORA 21894;Olfoxacin Acid;Oxygen-fluorine;AKOS BBS-00001807;OXYGEN-FLUORINE ACID;OTAVA-BB BB0111050010;DIFLUOROCARBOYLIC ACID
CBNumber
CB9427004
Molecular Formula
C13H9F2NO4
Formula Weight
281.21
MOL File
82419-35-0.mol
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Oxygen-fluorine acid Property

Melting point:
320-322 °C (lit.)
Boiling point:
459.2±45.0 °C(Predicted)
Density 
1.61±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Heated)
pka
4.87±0.40(Predicted)
color 
Off-White
BRN 
4202751
CAS DataBase Reference
82419-35-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
472670
Product name
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
Purity
97%
Packaging
5g
Price
$39.36
Updated
2024/03/01
TCI Chemical
Product number
O0404
Product name
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
Purity
>98.0%(HPLC)
Packaging
5g
Price
$83
Updated
2024/03/01
TCI Chemical
Product number
O0404
Product name
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
Purity
>98.0%(HPLC)
Packaging
25g
Price
$290
Updated
2024/03/01
Usbiological
Product number
009538
Product name
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid|
Packaging
1g
Price
$425
Updated
2021/12/16
TRC
Product number
D445745
Product name
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid(RS-OfloxacinCarboxylicAcid)
Packaging
10g
Price
$255
Updated
2021/12/16
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Oxygen-fluorine acid Chemical Properties,Usage,Production

Chemical Properties

Grey-Yellow Powder

Uses

9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (Ofloxacin EP Impurity A) is an Ofloxacin intermediate.

General Description

(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid may be used in the preparation of the following:

  • kynurenine aminotransferase II (KAT II) inhibitor, [(S)-(-)-9-(4-aminopiperazine-1-yl)-8-fluoro-3-methyl-6-oxo-2,3,5,6-tetrahydro-4H-1-oxa-3a-aza-phenalene-5-carboxylic acid]
  • fused-ring derivatives
  • N-desmethyllevofloxacin

Oxygen-fluorine acid Preparation Products And Raw materials

Raw materials

Sodium hydride Ethyl 2,3,4,5-tetrafluorobenzoyl acetate Acetic anhydride Potassium hydroxide Triethyl orthoformate DL-Alaninol Tetrahydrofuran Hydrochloric acid Dimethyl sulfoxide

Preparation Products

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Oxygen-fluorine acid Suppliers

Americas 1 Austria 1 Belgium 2 Canada 2 China 196 Europe 1 Germany 1 India 23 Japan 2 Switzerland 1 Ukraine 1 United Kingdom 6 United States 32 Global 269
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1390
Advantage
62
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
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Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
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59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
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64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5047
Advantage
50
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View Lastest Price from Oxygen-fluorine acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Oxygen-fluorine acid 82419-35-0
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg
Release date
2021-11-03
Hebei Yanxi Chemical Co., Ltd.
Product
Oxygen-fluorine acid 82419-35-0
Price
US $0.00/kg
Min. Order
1kg
Purity
98.50%
Supply Ability
20tons
Release date
2023-09-14
Henan Fengda Chemical Co., Ltd
Product
Oxygen-fluorine acid 82419-35-0
Price
US $36.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-16

82419-35-0, Oxygen-fluorine acidRelated Search:

Methyl salicylate Dihydromyrcenol 1-AdaMantanethylaMine Oxygen Ofloxacin Levofloxacin Tribenuron methyl Basic Violet 1 Methylparaben Methyl acrylate Kresoxim-methyl Methanol Levofloxacin carboxylic acid Piperazine 1-Piperazinecarbaldehyde 2,3,4,5-Tetrafluorobenzoyl chloride 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 10-amino-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S)- (9CI) Methyl

  • 9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-7H-PYRIDO[1,2,3-DE]-1,4-BENZ-OXAZINE-6-CARBOXYLIC ACID
  • 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxyllic acid
  • 9,10-DIFLUORO-3-METHYL-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLIC ACID
  • AURORA 21894
  • AKOS BBS-00001807
  • OXYGEN-FLUORINE ACID
  • OTAVA-BB BB0111050010
  • 9,10-Difluoro-2,3-Dihydro-3-Methyl-7-Oxo-7h-Pyroido(1,2,3-De)(1,4)Benzoxazine-6-Carboxylic Acid
  • Oxygen fluorine acid(FPA)
  • DIFLUOROCARBOYLIC ACID
  • 9,10-DIFLUORO-2,3-DIHYDRO-3-ME-7-OXO-7H- PYRIDO(1,2,3-DE)1,4-BENZOXAZINE-6-COOH
  • OFLOXACIN Q ACID
  • 9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro 7-H-Pyrido-1,2,3-DE]-1,4-Benzoxyazine-6-Carboxylic Acid
  • Oxygen-fluorine
  • 9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylicacid
  • 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3de]-1,4-benzoxazine
  • 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic
  • (RS)-9,10-Difluro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid (FPA)
  • 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
  • Ofloxacin Impurity 4(Ofloxacin EP Impurity A)
  • 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (RS-Ofloxacin Carboxylic Acid)
  • Ofloxacin EP IMpurity A
  • (RS)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
  • 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-DE]-1,4-benz-oxazine-6-carboxylic acid ,97%
  • 9,10-difluoro-2,3-dihydro-3-me-7-oxo-7h-pyrido-1,
  • Oxygen-fluorine acid ,98%
  • 9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBO
  • 7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLICACID,9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO
  • Olfoxacin Acid
  • Ofloxacin Impurity A(EP)
  • Ofloxacin-1
  • Levofloxacin Hydrochloride ImpurityⅡ: Impurity A(9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (RS-Ofloxacin Carboxylic Acid))
  • Ofloxacin Carboxylic Acid
  • 6,7-Difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
  • RS-Ofloxacin Carboxylic Acid
  • 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid&gt
  • Ofloxacin impurity A CRS
  • (RS)-9,10-Difluoro-3-methyl-7-oxo-2
  • (+/-)9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]lbenzoxazine-6-carboylic acid
  • Ofloxacin EP Impurity A (Ofloxacin Difluoro Carboxylic Acid)
  • Ofloxacin impurity A (O0120010)
  • Levofloxacin Hydrochloride ImpurityⅡ: Impurity A(9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (RS-Ofloxacin Carboxylic Acid))
  • Levofloxacin Hydrochloride ImpurityⅡ: Impurity A(9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid_x000b_(RS-Ofloxacin Carboxylic Acid))
  • Oxygen-fluorineacid Ethambutol dihydrochloride
  • 82419-35-0
  • C13H9F2NO4
  • C13H8F2NO4
  • Heterocyclic Building Blocks
  • Benzoxazines
  • Building Blocks
  • Various Intermediates
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Benzoxazines
  • Building Blocks
  • Heterocyclic Building Blocks
  • OFLOXACIN INTERMIDATE