Oxygen-fluorine acid

Product Name: Oxygen-fluorine acid
CAS No.: 82419-35-0
Chemical Name: Oxygen-fluorine acid
Synonyms: OFLOXACIN Q ACID;Ofloxacin Carboxylic Acid;Ofloxacin-1;AURORA 21894;Olfoxacin Acid;Oxygen-fluorine;AKOS BBS-00001807;OXYGEN-FLUORINE ACID;OTAVA-BB BB0111050010;DIFLUOROCARBOYLIC ACID
CBNumber: CB9427004
Molecular Formula: C13H9F2NO4
Formula Weight: 281.21
MOL File: 82419-35-0.mol

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Oxygen-fluorine acid Property

Melting point:: 320-322 °C (lit.)
Boiling point:: 459.2±45.0 °C(Predicted)
Density: 1.61±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly, Heated)
pka: 4.87±0.40(Predicted)
form: solid
color: Off-White
BRN: 4202751
CAS DataBase Reference: 82419-35-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 472670
Product name: 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
Purity: 97%
Packaging: 5g
Price: $39.36
Updated: 2024/03/01

TCI Chemical

Product number: O0404
Product name: 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $83
Updated: 2024/03/01

TCI Chemical

Product number: O0404
Product name: 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
Purity: >98.0%(HPLC)
Packaging: 25g
Price: $290
Updated: 2024/03/01

Usbiological

Product number: 009538
Product name: 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid|
Packaging: 1g
Price: $425
Updated: 2021/12/16

TRC

Product number: D445745
Product name: 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid(RS-OfloxacinCarboxylicAcid)
Packaging: 10g
Price: $255
Updated: 2021/12/16

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Oxygen-fluorine acid Chemical Properties,Usage,Production

Chemical Properties

Grey-Yellow Powder

Uses

9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (Ofloxacin EP Impurity A) is an Ofloxacin intermediate.

General Description

(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid may be used in the preparation of the following:

kynurenine aminotransferase II (KAT II) inhibitor, [(S)-(-)-9-(4-aminopiperazine-1-yl)-8-fluoro-3-methyl-6-oxo-2,3,5,6-tetrahydro-4H-1-oxa-3a-aza-phenalene-5-carboxylic acid]
fused-ring derivatives
N-desmethyllevofloxacin

Oxygen-fluorine acid Preparation Products And Raw materials

Raw materials

Sodium hydride Ethyl 2,3,4,5-tetrafluorobenzoyl acetate Acetic anhydride Potassium hydroxide Triethyl orthoformate DL-Alaninol Tetrahydrofuran Hydrochloric acid Dimethyl sulfoxide

Preparation Products

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Oxygen-fluorine acid Suppliers

Americas 1 Austria 1 Belgium 2 Canada 2 China 201 Europe 1 Germany 1 India 23 Japan 2 Switzerland 1 Ukraine 1 United Kingdom 6 United States 32 Global 274

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View Lastest Price from Oxygen-fluorine acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Oxygen-fluorine acid 82419-35-0
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1000kg
Release date: 2021-11-03

Hebei Yanxi Chemical Co., Ltd.

Product: Oxygen-fluorine acid 82419-35-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98.50%
Supply Ability: 20tons
Release date: 2023-09-14

Henan Fengda Chemical Co., Ltd

Product: Oxygen-fluorine acid 82419-35-0
Price: US $36.00-1.20/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-16

82419-35-0, Oxygen-fluorine acidRelated Search:

Methyl salicylate Dihydromyrcenol 1-AdaMantanethylaMine Oxygen Ofloxacin Levofloxacin Tribenuron methyl Basic Violet 1 Methylparaben Methyl acrylate Kresoxim-methyl Methanol Levofloxacin carboxylic acid Piperazine 1-Piperazinecarbaldehyde 2,3,4,5-Tetrafluorobenzoyl chloride 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 10-amino-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S)- (9CI) Methyl

9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-7H-PYRIDO[1,2,3-DE]-1,4-BENZ-OXAZINE-6-CARBOXYLIC ACID

9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxyllic acid

9,10-DIFLUORO-3-METHYL-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLIC ACID

AURORA 21894

AKOS BBS-00001807

OXYGEN-FLUORINE ACID

OTAVA-BB BB0111050010

9,10-Difluoro-2,3-Dihydro-3-Methyl-7-Oxo-7h-Pyroido(1,2,3-De)(1,4)Benzoxazine-6-Carboxylic Acid

Oxygen fluorine acid(FPA)

DIFLUOROCARBOYLIC ACID

9,10-DIFLUORO-2,3-DIHYDRO-3-ME-7-OXO-7H- PYRIDO(1,2,3-DE)1,4-BENZOXAZINE-6-COOH

OFLOXACIN Q ACID

9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro 7-H-Pyrido-1,2,3-DE]-1,4-Benzoxyazine-6-Carboxylic Acid

Oxygen-fluorine

9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylicacid

9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3de]-1,4-benzoxazine

9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic

(RS)-9,10-Difluro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid (FPA)

9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

Ofloxacin Impurity 4(Ofloxacin EP Impurity A)

9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (RS-Ofloxacin Carboxylic Acid)

Ofloxacin EP IMpurity A

(RS)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid

9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-DE]-1,4-benz-oxazine-6-carboxylic acid ,97%

9,10-difluoro-2,3-dihydro-3-me-7-oxo-7h-pyrido-1,

Oxygen-fluorine acid ,98%

9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBO

7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLICACID,9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO

Olfoxacin Acid

Ofloxacin Impurity A(EP)

Ofloxacin-1

Levofloxacin Hydrochloride ImpurityⅡ: Impurity A(9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid(RS-Ofloxacin Carboxylic Acid))

Ofloxacin Carboxylic Acid

6,7-Difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

RS-Ofloxacin Carboxylic Acid

9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid&gt

Ofloxacin impurity A CRS

(RS)-9,10-Difluoro-3-methyl-7-oxo-2

(+/-)9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]lbenzoxazine-6-carboylic acid

Ofloxacin EP Impurity A (Ofloxacin Difluoro Carboxylic Acid)

Ofloxacin impurity A (O0120010)

Levofloxacin Hydrochloride ImpurityⅡ: Impurity A(9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid_x000b_(RS-Ofloxacin Carboxylic Acid))

Oxygen-fluorineacid Ethambutol dihydrochloride

(RS)-9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid

82419-35-0

C13H9F2NO4

C13H8F2NO4

Heterocyclic Building Blocks

Benzoxazines

Building Blocks

Various Intermediates

Intermediates

Intermediates & Fine Chemicals

Pharmaceuticals

Benzoxazines

Building Blocks

Heterocyclic Building Blocks

OFLOXACIN INTERMIDATE