LAPACHOL
- Product Name
- LAPACHOL
- CAS No.
- 84-79-7
- Chemical Name
- LAPACHOL
- Synonyms
- Tecomin;CI 75490;LAPACHOL;NSC 11905;nsc-11905;taiguwood;Taigu Wood;Greenharten;Greenhartin;Groenhartin
- CBNumber
- CB1339480
- Molecular Formula
- C15H14O3
- Formula Weight
- 242.27
- MOL File
- 84-79-7.mol
LAPACHOL Property
- Melting point:
- 141-143 °C(lit.)
- Boiling point:
- 325.09°C (rough estimate)
- Density
- 1.2077 (rough estimate)
- refractive index
- 1.5740 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- ethanol: soluble10mg/mL, clear, light yellow to yellow
- pka
- 4.81±0.10(Predicted)
- form
- Solid
- Colour Index
- 75490
- color
- Yellow to Dark Yellow
- Merck
- 13,5382
- InChIKey
- CIEYTVIYYGTCCI-UHFFFAOYSA-N
- LogP
- 2.516 (est)
- CAS DataBase Reference
- 84-79-7
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- QL8750000
- Toxicity
- LD50 in male, female BALB/c mice (g/kg): 0.487; 0.792 orally (Morrison)
N-Bromosuccinimide Price
- Product number
- PHL89521
- Product name
- Lapachol
- Purity
- phyproof? Reference Substance
- Packaging
- 20mg
- Price
- $288
- Updated
- 2024/03/01
- Product number
- 142905
- Product name
- Lapachol
- Purity
- 98%
- Packaging
- 250mg
- Price
- $108
- Updated
- 2024/03/01
- Product number
- 30190
- Product name
- Lapachol
- Packaging
- 250mg
- Price
- $66
- Updated
- 2024/03/01
- Product number
- 30190
- Product name
- Lapachol
- Packaging
- 500mg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- 30190
- Product name
- Lapachol
- Packaging
- 100mg
- Price
- $36
- Updated
- 2024/03/01
LAPACHOL Chemical Properties,Usage,Production
Description
Lapachol, a benzoquinone, is a secondary allergen in teak (Tectona grandis).
Occurrence
Lapacol (CI Natural Yellow 16; CI 75490) (lapachic acid, taiguie acid, tecomin) is a yellow pigment occurring in the wood of trees of the genus Tecoma, native to the West Indies and tropical South America. The shavings of the wood, treated with lime water, give an extract that dyes cotton yellow.
Uses
Lapachol was used in the synthesis of the lapachol metal complexes.
Uses
antineoplastic, antifungal
Uses
It was used in the synthesis of the lapachol metal complexes.
Definition
ChEBI: Lapachol is a hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae. It has a role as a plant metabolite, an antineoplastic agent, an antibacterial agent and an anti-inflammatory agent. It is a hydroxy-1,4-naphthoquinone and an olefinic compound.
General Description
Lapachol is natural naphthoquinone compound derived from Bignoniaceae (Tabebuia sp.).
Contact allergens
Lapachol, a benzoquinone, is a secondary allergen in teak (Tectona grandis L., Verbenaceae family), a wood largely used for various indoor and outdoor applications (doors, windows, etc.) because of its strong durability. It has similar reactivity to deoxylapachol. Seealso Chap. 46
Biochem/physiol Actions
Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.
Purification Methods
Crystallise Lapachol from pet ether/EtOH, EtOH or Et2O. [Beilstein 8 H 326, 8 I 644, 8 II 365, 8 III 2720.]
LAPACHOL Preparation Products And Raw materials
Raw materials
Preparation Products
LAPACHOL Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
- Tel
- --
- Fax
- --
- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
View Lastest Price from LAPACHOL manufacturers
- Product
- LAPACHOL 84-79-7
- Price
- US $1.00/kg
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-24