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2-HYDROXYACETOPHENONE

Product Name
2-HYDROXYACETOPHENONE
CAS No.
582-24-1
Chemical Name
2-HYDROXYACETOPHENONE
Synonyms
2-hydroxy-1-phenylethan-1-one;2-Hydroxy-1-phenylethanone;Glycolophenone;BENZOYLCARBINOL;Ethanone, 2-hydroxy-1-phenyl-;PHENACYL ALCOHOL;Methanol, benzoyl-;RARECHEM AL BD 0384;2-hydroxy-1-ethanone;2-Hydroxyacetophenone
CBNumber
CB6293013
Molecular Formula
C8H8O2
Formula Weight
136.15
MOL File
582-24-1.mol
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2-HYDROXYACETOPHENONE Property

Melting point:
86-89 °C (lit.)
Boiling point:
126 °C / 12mmHg
Density 
1.0963
refractive index 
1.5470 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
13.09±0.10(Predicted)
form 
Powder
color 
Slightly yellow to orange
Water Solubility 
Soluble in water, ether, ethanol, chloroform.
Sensitive 
Air & Moisture Sensitive
InChI
1S/C8H8O2/c9-6-8(10)7-4-2-1-3-5-7/h1-5,9H,6H2
InChIKey
ZWVHTXAYIKBMEE-UHFFFAOYSA-N
SMILES
OCC(=O)c1ccccc1
LogP
0.721 (est)
CAS DataBase Reference
582-24-1(CAS DataBase Reference)
NIST Chemistry Reference
«alpha»-Hydroxyacetophenone(582-24-1)
EPA Substance Registry System
Ethanone, 2-hydroxy-1-phenyl- (582-24-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
TSCA 
TSCA listed
HS Code 
29144000
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
445134
Product name
2-Hydroxyacetophenone
Purity
98%
Packaging
5g
Price
$113
Updated
2026/03/19
Sigma-Aldrich
Product number
445134
Product name
2-Hydroxyacetophenone
Purity
98%
Packaging
25g
Price
$363
Updated
2026/03/19
TCI Chemical
Product number
H0347
Product name
2-Hydroxyacetophenone
Purity
>98.0%(GC)
Packaging
5g
Price
$61
Updated
2026/03/19
TCI Chemical
Product number
H0347
Product name
2-Hydroxyacetophenone
Purity
>98.0%(GC)
Packaging
25g
Price
$201
Updated
2026/03/19
TRC
Product number
H827820
Product name
2-Hydroxyacetophenone
Packaging
5g
Price
$45
Updated
2021/12/16
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2-HYDROXYACETOPHENONE Chemical Properties,Usage,Production

Chemical Properties

slightly yellow to orange powder

Uses

2-Hydroxyacetophenone can be used to produce 2-hydroxy-1-phenyl-ethanone-(1)-oxime by heating. It is used as pharmaceutical intermediate.

Uses

2-Hydroxyacetophenone can be used as a starting material for the synthesis of:

  • Enantioselective 1R-phenyl-1,2-ethanediol in the presence of a rhodium(III) catalyst by asymmetric transfer hydrogenation.
  • Copper(II) complexes of 2-hydroxyacetophenone N-substituted thiosemicarbazones.
  • Chromium, molybdenum, and ruthenium complexes of 2-hydroxyacetophenone Schiff bases.
  • 2-Hydroxyacetophenone-aroyl hydrazone derivatives for inhibition of copper corrosion in nitric acid.

Definition

ChEBI: 2-hydroxyacetophenone is a monohydroxyacetophenone that is acetophenone in which one of the methyl hydrogens has been replaced by a hydroxy group. It is a primary alcohol, a primary alpha-hydroxy ketone and a monohydroxyacetophenone.

Synthesis

Add 20 mmol of 48% hydrobromic acid to a 500 mL three-necked flask containing 20 mmol of styrene and 100 mL of water at room temperature, and slowly add 200 mmol of . 30% hydrogen peroxide, control the drip time for 30min, stir at room temperature for 30min, heat up to 80 , the reaction was 10h. C, the reaction was carried out for 10 h. The organic and aqueous phases were separated by standing. The organic phase containing 2-bromoacetophenone was added to a reactor containing 150 mL of water . The organic phase containing 2-bromoacetophenone was added to a reactor containing 150 mL of water , and hydrolyzed completely under the promotion of microwave, and the organic and aqueous phases were separated by standing to obtain a solution of 2-hydroxyacetophenone.

IC 50

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2-HYDROXYACETOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-HYDROXYACETOPHENONE Suppliers

Suzhou Lyran Biopharma And Technology CO.,LTD.
Tel
15556287180 15556287180
Email
1184800090@qq.com
Country
China
ProdList
332
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
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New Energy Chemicals
Tel
0515-82159099 13770142076
Fax
86-0515-8215909
Email
info@njuchem.com
Country
China
ProdList
251
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
Fax
021-67121385
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Sales-CN@TCIchemicals.com
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China
ProdList
24529
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Beijing HwrkChemical Technology Co., Ltd
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89508211 18501085097
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010-89508210
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sales.bj@hwrkchemical.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
ProdList
44802
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Secco work (Beijing) chemical technology co., LTD
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0566-8928158
Fax
010-69755668
Email
343367102@QQ.COM
Country
China
ProdList
360
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View Lastest Price from 2-HYDROXYACETOPHENONE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
2-HYDROXYACETOPHENONE 582-24-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
2-HYDROXYACETOPHENONE 582-24-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2018-08-16

582-24-1, 2-HYDROXYACETOPHENONERelated Search:


  • 2-hydroxy-1-phenyl-ethanon
  • 2-Hydroxy-1-phenylethanone
  • 2-Hydroxyethylphenyl ketone
  • Acetophenone, 2-hydroxy-
  • Acetophenone, alpha-hydroxy-
  • Ethanone, 2-hydroxy-1-phenyl-
  • Glycolophenone
  • Methanol, benzoyl-
  • omega-Hydroxyacetophenone
  • PHENACYL ALCOHOL
  • RARECHEM AL BD 0384
  • BENZOYLCARBINOL
  • 1-phenyl-2-hydroxyethanone
  • N-methyl-2-(4-oxanyloxy)benzamide
  • 2-hydroxy-1-phenylethan-1-one
  • 2-Hydroxyacetophenone,97+%
  • ALPHA-HYDROXYACETOPHENONE / 2-HYDROXYACETOPHENONE
  • 2-HYDROXY ACETOPHENONE98%MIN
  • 2-hydroxy-1-ethanone
  • Hydroxymethyl phenyl ketone
  • alpha-Hydroxyacetophenone,97%
  • 2-Hydroxyacetophenone
  • Benzoylcarbinol Phenacyl Alcohol
  • 2-hydroxy-1-phenylethaNAne
  • ALPHA-HYDROXYACETOPHENONE
  • 2-Hydroxyacetophenone ( Ortho Hydroxy Acetophenone)
  • Acetophenone Impurity 3
  • α-Hydroxyacetophenone
  • 582-24-1
  • C6H5COCH2OH
  • KETONE
  • Carbonyl Compounds
  • C7 to C8
  • Building Blocks
  • Ketones
  • Organic Building Blocks
  • C7 to C8
  • Carbonyl Compounds
  • Ketones