ChemicalBook > CAS DataBase List > IRL-1620

IRL-1620

Product Name
IRL-1620
CAS No.
142569-99-1
Chemical Name
IRL-1620
Synonyms
IRL-1620;SPI-1620;Sovateltide;IRL-1620, HUMAN;28: PN: WO2007112069 SEQID;M.W. 1820.97 C86H117N17O27;SUC-[GLU9, ALA11,15]-ENDOTHELIN-1 (8-21);N-SUC-[GLU9, ALA11,15]ENDOTHELIN-I (8-21);ENDOTHELIN-1(8-21), N-SUC-[GLU9, ALA11,15];SUCCINYL-(GLU9,ALA11,15)-ENDOTHELIN-1 (8-21)
CBNumber
CB1348183
Molecular Formula
C86H117N17O27
Formula Weight
1820.95
MOL File
142569-99-1.mol
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IRL-1620 Property

Boiling point:
2096.6±65.0 °C(Predicted)
Density 
1.347±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in DMSO
form 
powder
pka
3.39±0.10(Predicted)
color 
white
Water Solubility 
Soluble in water (0.5 mg/ml)
Sequence
Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J66049
Product name
IRL-1620
Packaging
0.5mg
Price
$87.7
Updated
2021/12/16
Alfa Aesar
Product number
J66049
Product name
IRL-1620
Packaging
1mg
Price
$139
Updated
2021/12/16
Tocris
Product number
1196
Product name
IRL-1620
Packaging
500U
Price
$212
Updated
2021/12/16
Usbiological
Product number
255523
Product name
IRL-1620
Packaging
500ug
Price
$466
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010221
Product name
IRL-1620
Purity
95.00%
Packaging
0.5MG
Price
$520
Updated
2021/12/16
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IRL-1620 Chemical Properties,Usage,Production

Biological Activity

IRL-1620 is a potent and selective endorphin receptor (endothelin receptor) type B agonist with a Ki of 16 pM.

in vitro

IRL-1620 is the most potent and specific ligand for the ETB receptor (K i ETA/ K i ETB=120,000) as judged by the K i values for ETA (19 μM) and ETB (16 PM) receptors. IRL-1620 is 60 times more selective for the ETB receptor than ET-3 (K i ETA /K i ETB=1,900).

target

IC50: 16 pM (Endothelin receptor B), 19 μM (Endothelin receptor A)

storage

-20°C (desiccate)

IRL-1620 Preparation Products And Raw materials

Raw materials

Preparation Products

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IRL-1620 Suppliers

Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
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View Lastest Price from IRL-1620 manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Sovateltide 142569-99-1
Price
US $70.00-700.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-30
Career Henan Chemical Co
Product
IRL-1620 142569-99-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-13

142569-99-1, IRL-1620Related Search:


  • IRL-1620, HUMAN
  • IRL-1620
  • ENDOTHELIN-1(8-21), N-SUC-[GLU9, ALA11,15]
  • N-SUC-[GLU9, ALA11,15]ENDOTHELIN-I (8-21)
  • N-SUCCINYL-[GLU9, ALA11,15]-ENDOTHELIN, 8-21
  • SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP
  • SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
  • SUCCINYL-(GLU9,ALA11,15)-ENDOTHELIN-1 (8-21)
  • SUC-[GLU9, ALA11,15]-ENDOTHELIN-1 (8-21)
  • SUC-[GLU9, ALA11, 15] ENDOTHELIN-1 (8-21), HUMAN
  • IRL-1620(ENDOTHELIN-1(8-21), N-SUC-(GLU9 ,ALA11,15) SYNTHETIC >97%
  • n-succinyl-[glu9, ala11,15]-endothelin 1 fragment 8-21
  • IRL-1620, N-Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp, N-Succinyl-[Glu9, Ala11,15]-Endothelin1 fragment 8-21
  • M.W. 1820.97 C86H117N17O27
  • IRL-1620;N-SUCCINYL-[GLU9, ALA11,15]-ENDOTHELIN 1 FRAGMENT 8-21
  • SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP: SUC-DEEAVYFAHLDIIW
  • Endothelin-1 (8-21), succinyl-(Glu(9),Ala(11,15))-
  • L-Tryptophan, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-tyrosyl-L-alanyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-
  • Succinyl-(glutamyl(9)-alanyl(11,15))-endothelin-1 (8-21)
  • SPI-1620
  • 28: PN: WO2007112069 SEQID
  • N-(3-Carboxy-1-oxopropyl)-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-alanyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-L-tryptophan
  • N-Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp
  • Succinyl-(Glu9,Ala1115)-Endothelin-1 (8-21), IRL-1620
  • L-Tryptophan, N-(3-carboxy-1-oxopropyl)-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-alanyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl-
  • Sovateltide
  • Succinyl-[Glu9,Ala11,15]-Endothelin-1 (8-21) / Sovateltide
  • Succinyl-(Glu?,Ala??·??)-Endothelin-1 (8-21)
  • 142569-99-1
  • C86H117N17O27
  • Endothelins
  • Peptides
  • Agonist
  • Amino Acids and Peptides
  • BioChemical
  • Biochemicals and Reagents
  • Endothelin receptor