4-HYDROXYMETHYL-5-METHYLIMIDAZOLE

Product Name: 4-HYDROXYMETHYL-5-METHYLIMIDAZOLE
CAS No.: 29636-87-1
Chemical Name: 4-HYDROXYMETHYL-5-METHYLIMIDAZOLE
Synonyms: Cimetidine Impurity I;4-Methyl-5-imidazolemethanol;Cimetidine Impurity I HCl(EP);5-methyl-1h-imidazole-4-methano;4-Hydoxymethyl-5-methylimidazol;5-methyl-1H-imidazole-4-methanol;4-Methyl-1H-imidazole-5-methanol;5-Hydroxymethyl-4-methylimidazole;4-HYDROXYMETHYL-5-METHYLIMIDAZOLE;5-METHYL-4-HYDROXYMETHYLIMIDAZOLE
CBNumber: CB1360451
Molecular Formula: C5H8N2O
Formula Weight: 112.13
MOL File: 29636-87-1.mol

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4-HYDROXYMETHYL-5-METHYLIMIDAZOLE Property

Melting point:: 136°C
Boiling point:: 389.1±27.0 °C(Predicted)
Density: 1.231
storage temp.: 2-8°C
solubility: DMSO (Heated), Methanol (Slightly)
form: Solid
pka: 13.62±0.10(Predicted)
color: White to Off-White
Water Solubility: almost transparency
Major Application: pharmaceutical small molecule
InChI: InChI=1S/C5H8N2O/c1-4-5(2-8)7-3-6-4/h3,8H,2H2,1H3,(H,6,7)
InChIKey: AXJZCJSXNZZMDU-UHFFFAOYSA-N
SMILES: C1NC(CO)=C(C)N=1
LogP: -0.62 at 23℃ and pH8.4
CAS DataBase Reference: 29636-87-1(CAS DataBase Reference)
EPA Substance Registry System: 1H-Imidazole-4-methanol, 5-methyl- (29636-87-1)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
WGK Germany: WGK 3
TSCA: TSCA listed
HS Code: 2933299090
Storage Class: 8A - Combustible corrosive hazardous materials
Hazard Classifications: Acute Tox. 4 Oral
Skin Corr. 1B

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2260
Product name: Cimetidine Impurity I
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 50mg
Price: $916
Updated: 2025/07/31

TCI Chemical

Product number: H0976
Product name: 4-Hydroxymethyl-5-methylimidazole
Purity: >96.0%(GC)(T)
Packaging: 5g
Price: $51
Updated: 2025/07/31

TCI Chemical

Product number: H0976
Product name: 4-Hydroxymethyl-5-methylimidazole
Purity: >96.0%(GC)(T)
Packaging: 25g
Price: $155
Updated: 2025/07/31

TRC

Product number: H005070
Product name: 4-Hydroxymethyl-5-methylimidazole
Packaging: 50mg
Price: $50
Updated: 2021/12/16

TRC

Product number: H005070
Product name: 4-Hydroxymethyl-5-methylimidazole
Packaging: 100mg
Price: $70
Updated: 2021/12/16

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4-HYDROXYMETHYL-5-METHYLIMIDAZOLE Chemical Properties,Usage,Production

Uses

4-Hydroxymethyl-5-methylimidazole is used as an intermediate of Alosetron hydrochloride, a 5-HT3 antagonist used only for the treatment of irritable bowel syndrome (IBS) in women with predominantly severe diarrhoea. As the drug causes ischaemic colitis, a life-threatening condition in which intestinal tissue dies due to lack of blood flow to the colon. Therefore, it is no longer used.

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXYMETHYL-5-METHYLIMIDAZOLE Suppliers

Americas 1 China 122 Europe 1 Germany 2 India 8 Japan 1 Ukraine 2 United Kingdom 8 United States 17 Global 162

Nanjing Lift Pharmaceutical Technology Co., Ltd.

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View Lastest Price from 4-HYDROXYMETHYL-5-METHYLIMIDAZOLE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: (4-Methyl-1H-imidazol-5-yl)methanol 29636-87-1
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-27

Career Henan Chemical Co

Product: 4-HYDROXYMETHYL-5-METHYLIMIDAZOLE 29636-87-1
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2020-01-08

29636-87-1, 4-HYDROXYMETHYL-5-METHYLIMIDAZOLERelated Search:

(5-Ethyl-1H-imidazol-4-yl)methanol 2-Cyaniminothiazolidine N-Cyanoimido-S,S-dimethyl-dithiocarbonate CIMETIDINE SULPHOXIDE DIHYDROCHLORIDE 4-[[(2-aminoethyl)thio]methyl]-5-methylimidazole Cimetidine Amide Dihydrochloride Cimetidine N-Cyano-3-(cyanoaMino)-N'-Methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-iMidaMide (CiMetidine IMpurity) 2-cyano-1,3-bis(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine N-Cyano-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]carbamimidic acid methyl ester N-cyano-N',N''-dimethylguanidine CIMETIDINE DIHYDROCHLORIDE IMP D Cysteamine hydrochloride Cimetidine Impurity 3 4,5-Imidazoledicarboxylic acid Dimethyl 4,5-imidazoledicarboxylate 4-Methyl-5-imidazolemethanol hydrochloride Imidazole-4-methanol

5-methyl-1h-imidazole-4-methano

(5-METHYL-1H-IMIDAZOL-4-YL)-METHANOL

5-METHYL-4-HYDROXYMETHYLIMIDAZOLE

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE

5-methyl-1H-imidazole-4-methanol

4-hydroxymethyl-5-methylimidazole base

5-Hydroxymethyl-4-methylimidazole

4-(Hydroxymethyl)-5-methyl-1H-imidazole

4-Methyl-1H-imidazole-5-methanol

4-Methyl-5-(hydroxymethyl)-1H-imidazole

4-Methyl-5-hydroxymethyl-1H-imidazole

4-Methyl-5-imidazolemethanol

(4-Methyl-1H-imidazol-5-yl)methanol

Cimetidine Impurity I HCl(EP)

4-Hydoxymethyl-5-methylimidazol

4-Hydroxymethyl-5-methylimidazole&gt

1H-Imidazole-5-methanol, 4-methyl-

Cimetidine Impurity 15（Cimetidine EP Impurity I）

29636-87-1 (1H-Imidazole-5-methanol,4-methyl- )

Cimetidine Impurity I

4-Hydroxy methyl-5-methyl-imidazole free base

29636-87-1

pharmacetical

Imidazol&Benzimidazole