4,5-Imidazoledicarboxylic acid
- Product Name
- 4,5-Imidazoledicarboxylic acid
- CAS No.
- 570-22-9
- Chemical Name
- 4,5-Imidazoledicarboxylic acid
- Synonyms
- edicarboxyL;AKOS AUF2071;4,5-ImidazoL;AKOS BBS-00002898;IFLAB-BB F1918-0019;RARECHEM AL BO 1102;4,5-Dicarboxymidazole;4,5-Dicarboxyimidazole;4,5-Imidazoledicarboxylate;4,5-iMidazole dicarboxylic
- CBNumber
- CB0401861
- Molecular Formula
- C5H4N2O4
- Formula Weight
- 156.1
- MOL File
- 570-22-9.mol
4,5-Imidazoledicarboxylic acid Property
- Melting point:
- 280-285 °C (dec.) (lit.)
- Boiling point:
- 280.29°C (rough estimate)
- bulk density
- 650-660kg/m3
- Density
- 1,749 g/cm3
- refractive index
- 1.4800 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- 0.5g/l
- pka
- 3.59±0.10(Predicted)
- form
- Fine Crystalline Powder
- color
- Light yellow to yellow-brown
- PH
- 3.7 (0.5g/l, H2O, 20℃)
- Water Solubility
- 0.5g/L(20 ºC)
- BRN
- 147774
- InChIKey
- ZEVWQFWTGHFIDH-UHFFFAOYSA-N
- CAS DataBase Reference
- 570-22-9(CAS DataBase Reference)
- NIST Chemistry Reference
- 4,5-Imidazole dicarboxylic acid(570-22-9)
- EPA Substance Registry System
- 1H-Imidazole-4,5-dicarboxylic acid (570-22-9)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- NI4760000
- Autoignition Temperature
- 430°C
- TSCA
- Yes
- HS Code
- 29332990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 246115
- Product name
- 4,5-Imidazoledicarboxylic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $66.1
- Updated
- 2023/06/20
- Product number
- 246115
- Product name
- 4,5-Imidazoledicarboxylic acid
- Purity
- 97%
- Packaging
- 25g
- Price
- $176
- Updated
- 2022/05/15
- Product number
- I0003
- Product name
- 1H-Imidazole-4,5-dicarboxylic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $61
- Updated
- 2025/07/31
- Product number
- I0003
- Product name
- 1H-Imidazole-4,5-dicarboxylic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $102
- Updated
- 2021/12/16
- Product number
- I387515
- Product name
- 4,5-Imidazoledicarboxylic acid
- Packaging
- 50g
- Price
- $250
- Updated
- 2021/12/16
4,5-Imidazoledicarboxylic acid Chemical Properties,Usage,Production
Chemical Properties
light yellow to yellow-brown fine cryst. powder
Uses
4,5-Imidazoledicarboxylic Acid is an intermediate used in the synthesis of N-substituted cyclic imides with anticancer and anti-inflammatory activities. it is also used to prepare imidazolecarboxamide derivatives with cannabinoid CB2 receptor antagonistic activities.
Uses
4,5-Imidazoledicarboxylic acid is an imidazole used for research purposes.
Synthesis
5465-29-2
570-22-9
General procedure: 800 ml of concentrated sulfuric acid (80% concentration) was slowly added to 200 ml of water to form a reaction system. To this system was added 50.0 g of 2-propylbenzimidazole, followed by the slow dropwise addition of 30 mL of hydrogen peroxide to 500 mL of the reaction mixture. The reaction is exothermic and causes reflux, and the rate of titration needs to be controlled to maintain the reaction solution at a boil. After completion of the reaction, stirring was continued for 3 hours. Subsequently, 1000 mL of water was added to the reaction mixture and cooled to room temperature. The mixture was stirred for 3 hours at 0 to 5°C to promote precipitation of solids. The solid was collected by filtration and washed sequentially with water and 5% aqueous sodium sulfite solution (100 mL). The resulting solid was purified by column chromatography using water: methanol = 2:1 as eluent to give the final imidazole-4,5-dicarboxylic acid 3-lg with a melting point of 267.3 °C (simultaneous decomposition).
References
[1] Patent: CN104262260, 2016, B. Location in patent: Paragraph 0093-0095
4,5-Imidazoledicarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
4,5-Imidazoledicarboxylic acid Suppliers
- Tel
- 0512-66627360 13914021065
- Fax
- 0512-66627360
- 706938434@qq.com
- Country
- China
- ProdList
- 237
- Advantage
- 60
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-61259138 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
- Advantage
- 69
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- sales@jonln.com
- Country
- China
- ProdList
- 1995
- Advantage
- 65
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- +86 351 7031519
- Fax
- +86 351 7031519
- sales@RHFChem.com
- Country
- China
- ProdList
- 2338
- Advantage
- 56
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 18515581800 18501085097
- Fax
- 010-89508210
- sales.bj@hwrkchemical.com
- Country
- China
- ProdList
- 9400
- Advantage
- 55
View Lastest Price from 4,5-Imidazoledicarboxylic acid manufacturers
- Product
- 4,5-Imidazoledicarboxylic acid 570-22-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2025-08-15
- Product
- 4,5-Imidazoledicarboxylic acid 570-22-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-10
- Product
- 4,5-Imidazoledicarboxylic acid 570-22-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11