1H-Imidazole-2-carboxylic acid
- Product Name
- 1H-Imidazole-2-carboxylic acid
- CAS No.
- 16042-25-4
- Chemical Name
- 1H-Imidazole-2-carboxylic acid
- Synonyms
- IMIDAZOLE-2-CARBOXYLIC ACID;TIMTEC-BB SBB010014;RARECHEM AL BE 0666;2-Carboxy-1H-imidazole;2-Imidazolecarboxylic acid;1H-pyrazole-2-carboxylic acid;1H-Imidazol-2-carboxylic acid;1H-IMIDAZOLE-2-CARBOXYLIC ACID;2-IMidazolecarboxylic Acid Hydrate;1H-IMIDAZOLE-2-CARBOXYLIC ACID 97%
- CBNumber
- CB9112690
- Molecular Formula
- C4H4N2O2
- Formula Weight
- 112.09
- MOL File
- 16042-25-4.mol
1H-Imidazole-2-carboxylic acid Property
- Melting point:
- 198 °C
- Boiling point:
- 407.9±28.0 °C(Predicted)
- Density
- 1.524±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- form
- powder to crystal
- pka
- 1.44±0.10(Predicted)
- color
- White to Dark blue
- λmax
- 247nm(lit.)
- BRN
- 112615
- CAS DataBase Reference
- 16042-25-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 22-26-36/37/39-36
- HazardClass
- IRRITANT
- HS Code
- 2933299090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS019334
- Product name
- Imidazole-2-carboxylic acid
- Purity
- Aldrich
- Packaging
- 100mg
- Price
- $185
- Updated
- 2025/07/31
- Product number
- I1008
- Product name
- 2-Imidazolecarboxylic Acid
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $85
- Updated
- 2025/07/31
- Product number
- I1008
- Product name
- 2-Imidazolecarboxylic Acid
- Purity
- >98.0%(HPLC)
- Packaging
- 5g
- Price
- $292
- Updated
- 2025/07/31
- Product number
- I0867
- Product name
- 2-Imidazolecarboxylic Acid Hydrate
- Purity
- >98.0%(HPLC)
- Packaging
- 5g
- Price
- $244
- Updated
- 2021/12/16
- Product number
- I0867
- Product name
- 2-Imidazolecarboxylic Acid Hydrate
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
1H-Imidazole-2-carboxylic acid Chemical Properties,Usage,Production
Synthesis Reference(s)
The Journal of Organic Chemistry, 60, p. 1090, 1995 DOI: 10.1021/jo00109a052
Synthesis
10111-08-7
16042-25-4
General procedure for the synthesis of imidazole-2-carboxylic acid from 2-imidazolecarboxaldehyde: 30% aqueous H2O2 solution (10 g) was slowly added dropwise to stirred aqueous 2-imidazolecarboxaldehyde (2.88 g, 0.030 mol) solution (10 ml). The reaction was continued at room temperature for 72 hours. After completion of the reaction, water was removed by distillation under reduced pressure at room temperature to give a white crystalline solid. The resulting solid was washed with stirred diethyl ether/water (4:1) mixture to remove residual peroxide. Note: Heating may cause decarboxylation to occur. The yield was 97.5%. Melting point (MP) was 156-158 °C. 1H NMR (400 MHz, D2O): δ 7.56 (2H, s, imidazolium ring-H); 13C NMR (400 MHz, D2O): δ 158.86, 141.02, 120.49 ppm. IR (KBr, cm-1): 3392 (m), 3124 (m), 2861 ( m), 1618 (s), 1502 (m), 1462 (m), 1421 (s), 1388 (s), 1322 (m), 1108 (s), 925 (s), 910 (s), 819 (m), 797 (s), 774 (m). Calculated values for elemental analysis (C4H6N2O3, 130.11): C, 36.92%; H, 4.65%; N, 21.53%. Measured values: C, 37.18%; H, 4.94%; N, 21.47%.
References
[1] Journal of Inorganic Biochemistry, 2015, vol. 145, p. 11 - 18
1H-Imidazole-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-Imidazole-2-carboxylic acid manufacturers
- Product
- 1H-Imidazole-2-carboxylic acid 16042-25-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 1H-Imidazole-2-carboxylic acid 16042-25-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 1H-Imidazole-2-carboxylic acid 16042-25-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2018-08-06